Cholesterol is not a metabolic fuel. It is a structural component of cell membrane, precursor for steroid hormones and Vit. D. Its synthesis, absorption and elimination are intricately balanced. Cholesterol synthesis shares the same enzymatic machinery with ketone bodies
Nadir
1,816 posts
Reformed Interventional cardiologist prescribing and following patients on LCHF diet
Webster, TX
Joined June 2017
- If I asked a lipidologist to name a biologic role of LDL, they would look at me as if I have lost my mind. If I list Cell Repair Host Defense Carries for fat soluble vit. They would think that I am a conspiracy theorist! To those I offer a free ticket to lowcarbhouston.com
- Atorvastatin leads to an increased risk of fatal strokes in 4-D randomized study in pts with T2D & ESRD. There was no benefit in overall mortality or non fatal MI. ⬇️ in LDL was 41%. How do the statin defenders explain this paradox @Drlipid @brianedwardsmd @LDLSkeptic
- New study on short term intermittent fasting showing fat loss, preservation of lean mass and improvement in IR @drjasonfung @JeffryGerberMD @meganjramos. Don't have Dr. Phinney's Twitter handle
- Pt. called with atrial fibrillation. Young man - 40s. Was given Protonix (a stomach acid blockers & seemingly benign). Med ⬇️ magnesium absorption, which can exacerbate an underlying predisposition for the heart rhythm. Many ways in which modern medicine contributes to disease
- At the LCAN meeting to address the DGA committee of USDA. If given the opportunity for verbal comment, what should I say - please see my comments below @natureboyrr @drjasonfung @JeffryGerberMD @meganjramos @bigfatsurprise @FatEmperor @drandyphung @weamonette @lowcarbGP
- An open letter to Bernie Sanders. Given his recent heart attack & stents, I want him to have an alternative viewpoint quite different from mainstream medicine about #statins &#lowfathealthywholegraindiet. Help disseminate this by retweeting @FatEmperor @LDLSkeptic @DaveKeto
- Cholesterol is lower in the brain of patients with schizophrenia (SZ), major depressive disorder (MDD) & major bipolar disorder (MBD) compared to control (Con). Should we discuss these associations before initiating 4-5 decades of statin therapy with patients @Drlipid @LDLSkeptic
- Optimal cellular function requires autophagy. This is promoted by intermittent fasting and exercise (eustress) @OZmandia @KenDBerryMD @FatEmperor @JeffryGerberMD @DrRamonIssa @drandyphung @natureboyrr
- Honored to attend Carnivore conference and get a chance to be pictured with someone who has touched so many lifes positively @SBakerMD @KetoCarnivore
- Ketone body (KB) production and cholesterol synthesis share common metabolic pathway - information that has not been widely disseminated in the LC community. Thus, increase in KB with fasting will by default increase both cholesterol and LDL cholesterol. See figures below...
- Early obesity is characterized by beta cell hypertrophy. Understanding how hyperinsulinemia, IR, glucagon & insulin/glucagon ratio contributes to nutrient homeostasis in obesity is key to understanding metabolic syndrome. Our focus should be on this rather than drugs @meganjramos
- I have seen this practice routinely taken to extreme. Patients with dementia and in wheel chairs, the statins are continued as if they are miracle drugs that should not be stopped. When will physicians wake up and realize that they have abdicated their critical thinking to PharmaReplying to @jonnywatt @timos_m and 10 othersThis is a meta-analysis looking more specifically at the effect of statins on all cause mortality for secondary prevention in the elderly, a common group in clinical practice. onlinejacc.org/content/51/1/37



























