James Fickel (@jamesfickel) / X

James Fickel

106 posts

James Fickel

@jamesfickel

Joined October 2012

Pinned
James Fickel
@jamesfickel
Mar 5
The Foundations of Tomorrow The transition to AGI needs to go well. We’ve deployed $350M+ to neuroAI, longevity, and more with the belief that the brain is the key to better, safer AGI. This is the first of many overview posts on our thinking.
The Foundations of Tomorrow
From blog.amaranth.foundation
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James Fickel
@jamesfickel
Dec 14, 2020
Launching opengrants.com today! Easily create long-term incentives for Ethereum public goods creators. Point ETH payment streams at payment splitter contracts to incentivize developers en masse. The smart contracts have been audited by @sigp_io jamesfickel.ghost.io/towards-long-t…
James Fickel
@jamesfickel
Nov 14, 2023
This report is the months-long culmination of some of the brightest young leaders in the longevity field coming together to prioritize and detail the field’s top bottlenecks:
amaranth.foundation
Bottlenecks of Aging — Amaranth Foundation
Discover Amaranth Foundation's groundbreaking work in longevity and neuroscience. Led by experts like James Fickel, Joanne Peng, Raiany Romanni, and Rohan Krajeski.
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James Fickel
@jamesfickel
Nov 28, 2023
Past the age of 35, our brains shrink between 0.2-0.5% every year. We gathered leading neuroscientists to evaluate the most promising avenues for addressing brain aging:
Rohan Krajeski
@RohanKrajeski
Nov 28, 2023
Delighted to announce the release of the Amaranth Foundation's latest white paper on combating brain aging (and 🧵👇): static1.squarespace.com/static/64becfb…
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James Fickel
@jamesfickel
Aug 7, 2024
Very happy to be backing the Enigma Project at Stanford. I believe we need to understand the brain asap in order to design safe general intelligence
Sophia Sanborn
@naturecomputes
Aug 6, 2024
New project: enigmaproject.ai Engineers, ML researchers, mech interp community: Reach out if you're interested in getting involved
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James Fickel
@jamesfickel
Nov 14, 2023
Replying to @jamesfickel
These bottlenecks are broken into projects with identified leads that need funding and/or talent. I started the Amaranth Foundation a couple of years ago to fund ambitious longevity research. Alongside some of the brightest young minds in the field, we’ve given out dozens of
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James Fickel
@jamesfickel
Dec 14, 2020
Replying to @jamesfickel
I’m going to help kickstart things by pointing a 3600 ETH payment stream at an eth2 contributors grant that pays out over 3 years. This grant covers client teams and researchers and was crafted with input from knowledgable community members. opengrants.com/grant/0x53e7da…
James Fickel
@jamesfickel
Nov 11, 2019
Releasing a standard for open grants on Ethereum. With this standard, a list of grantees can be batched into a single donation address. These grants are auditable and composable. Complex distributions of grants can be reduced to a single address.
Open Grants Standard ERC
From medium.com
James Fickel
@jamesfickel
Dec 28, 2024
Replying to @getjonwithit
Wouldn’t the simulation likely be using dynamic loading or just-in-time rendering that obeys any proof of inefficiency that you generate? It could be incredibly efficient with algorithms generated by an ASI. How do we know the set of computation isn’t saturated with simulations?
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James Fickel
@jamesfickel
Dec 14, 2020
Replying to @jamesfickel
Huge thanks to @noah_eth @ameensol @jaclynlenee @dan13ram @vengist @trentvanepps and @raidguild for making this possible I love the eth community 😊❤️🦄
James Fickel
@jamesfickel
Dec 14, 2020
Replying to @jamesfickel
It would be great to see more incentive programs created to reward people doing valuable open source work. Kindly help fund the long-term development of the platform that has enabled so much for the blockchain ecosystem, especially if you’re a whale 🐳
James Fickel
@jamesfickel
Dec 14, 2020
Replying to @jamesfickel
Explicit long-term incentives have been a missing feature in the Ethereum ecosystem partially due to regulatory risk and devs being very busy. ETH options and time-locked contracts fall under US swap regulations, but cancellable ETH payment streams have no such legal obstacles.
James Fickel
@jamesfickel
Nov 28, 2023
Replying to @cz_binance
David Sinclair
@davidasinclair
Nov 14, 2023
Well done @jamesfickel & the Amaranth Foundation team. A must read for anyone interested in the future of human health. By placing early bets on outstanding people & projects, Amaranth is filling the funding gap to facilitate moonshot approaches to longevity 👏🙏
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James Fickel
@jamesfickel
Aug 7, 2024
Replying to @KarlPfleger
We have no experience dealing with agents that are more capable than us in every dimension. Hopefully, understanding the brain’s architecture will allow us to bound agent capabilities to something we’re relatively familiar with. I don’t think building AGI will ever be risk free.
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