David Sinclair (@davidasinclair) / X

David Sinclair

10.6K posts

David Sinclair

@davidasinclair

Professor researching why we age & how to reverse it. Author & host of Lifespan. Mission: Extend healthy life for all. Views are entirely his own. @joinlifespan

Harvard

lifespan.com

Born June 26

Joined March 2012

Pinned
David Sinclair
@davidasinclair
Jun 9
30 years of research came down to one moment. Was honored to be there. Congrats to the team! 👏
Lifespan
@JoinLifespan
Jun 9
Today, @lifebiosciences confirmed the first patient has been dosed with an epigenetic restoration drug candidate. An exciting milestone 🚀 Life Biosciences is the OG cellular rejuvenation using epigenetic restoration to reverse diseases of aging. It was cofounded by
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David Sinclair
@davidasinclair
Apr 10, 2020
For those who wanted a world without vaccines, witness the world without one vaccine.
David Sinclair
@davidasinclair
Mar 14, 2020
Since my Harvard lab closed yesterday, I've been reading and interpreting this week's published papers on #COVID19. What follows is a thread of information, my interpretation, links to sources & predictions. Let's start with what you need to know... #coronavirus #COVIDー19
David Sinclair
@davidasinclair
Feb 16, 2024
Dude, in that photo I was 35 🤦‍♂️
Brainflow 🧬
@Brainflow_
Feb 16, 2024
The exact longevity supplements that Harvard scientist Dr. David Sinclair uses. He's 54 but literally looks 35. -An overview of 13 supplements/drugs -Their underlying logic -Recommended dosages (Save this thread for reference) THREAD🧵
Readers added context
Dr. Sinclair was 35 at the time of this photo twitter.com/davidasinclair…
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David Sinclair
@davidasinclair
Jul 12, 2023
This new discovery offers the potential to reverse aging with a single pill, with applications ranging from improving eyesight to effectively treating age-related diseases 14/17
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David Sinclair
@davidasinclair
Apr 9, 2023
Disagree @elonmusk. Studies of identical twins show longevity is 80-90% epigenetic, meaning it can be changed by lifestyle, for the same reason a queen bee raised on royal jelly can live 10 times longer than a genetically identical worker 🐝
Elon Musk
@elonmusk
Apr 9, 2023
Replying to @paulg
Our lifespan is programmed into our genes, just like it is for fruit flies or pets. Fruit are already vegan & even if they do yoga every day & take every supplement, they still only live 50 days.
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David Sinclair
@davidasinclair
Jul 15, 2025
5 minutes in a sauna 4x/week reduces cardiovascular risk by 50%
Readers added context they thought people might want to knowReaders added context
Finnish data often cited here looked at men taking 4-7 sauna sessions a week lasting ≈ 15-20 min. That group had ~50 % lower cardiovascular death than men with 1 session. Five-minute sessions weren’t studied, and the study shows association, not proof of cause. Source: pubmed.ncbi.nlm.nih.gov/25705824/
Context is written by people who use X, and appears when rated helpful by others. Find out more.
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David Sinclair
@davidasinclair
Feb 4, 2025
Omega-3 plus vitamin D “slows biological aging by 3-4 months over 3 years, particularly when combined with exercise.” 👏
Prof Steve Horvath
@prof_horvath
Feb 3, 2025
Omega-3 supplements slow biological ageing nature.com/articles/d4158…
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David Sinclair
@davidasinclair
Aug 11, 2025
Lifting weights isn't vanity, it’s life insurance. Strength training cuts risks of all‑cause death by ~17%
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David Sinclair
@davidasinclair
Jul 14, 2025
Muscle mass predicts lifespan better than BMI or weight - so get moving and get lifting
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David Sinclair
@davidasinclair
Apr 18, 2022
The longer your food lasts, the shorter you will
David Sinclair
@davidasinclair
Jan 12, 2023
Delighted to share with you our latest paper. Here, we test the hypothesis that aging may be driven by DNA damage-induced changes to the epigenome. Mightbe due to a glitch in the software of the body that causes it to malfunction, which can be fixed with a reboot?👇 1/
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David Sinclair
@davidasinclair
Feb 17, 2023
New paper provides evidence that black holes are the origin of dark energy & the expansion of the universe. Yeah, that’s a big deal
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David Sinclair
@davidasinclair
Sep 20, 2025
I came on an H1B “specialty occupation” visa and there’s no way I could have afforded a $100K fee. The US has just made it virtually impossible for people like me to come here
Zakka Jacob
@Zakka_Jacob
Sep 20, 2025
Trump just killed the H1B visa. Companies now have to pay $100K per year to bring foreign hi-skilled workers to the U.S. This will dissuade them from doing so, some jobs will be offshored. For Indian techies, the American dream just got killed.
Rapid Response 47
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Rapid Response 47
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