Max Gulhane MD (@MaxGulhaneMD) / X

Max Gulhane MD

3,077 posts

Max Gulhane MD

@MaxGulhaneMD

Reverse engineering chronic disease.

Tweets not medical advice

linktr.ee/maxgulhanemd

Joined September 2022

Max Gulhane MD
@MaxGulhaneMD
Sep 11, 2025
Melatonin is the ultimate anti-oxidant, lubricator of mitochondrial engines and guardian of mtDNA Modern living prevents melatonin production - lack of daytime sunlight (NIR light) - excess light at night (blue/green) Chronic diseases as accelerated aging phenotype due to
Jonathan Jarecki
@Jonathanjarecki
Aug 18, 2025
Melatonin both as a chemical expression of darkness and a participant of sunlight exposure:
58K
Max Gulhane MD
@MaxGulhaneMD
Aug 11, 2023
The clinical focus on LDL and total cholesterol for prevention of aethrosclerotic cardiovascular disease (ASCVD) is to the exclusion of underlying root causes, which are readily modifiable by easily implemented lifestyle interventions - short thread
178K
Max Gulhane MD
@MaxGulhaneMD
Jun 8, 2024
The unstated nuance in this whole dietary debate is that environmental signals - specifically LIGHT & TEMPERATURE dictate the suitability of different diets Strict carnivore is effectively a ‘wintertime’ diet, because animals are the only food source in low UV conditions of high
Paul Saladino, MD
@paulsaladinomd
Jun 7, 2024
Here is why I quit the carnivore diet… In 2018 I began a carnivore diet (meat, organs, salt, eggs) curious if this would help my long-standing autoimmune issues - eczema and asthma. Eating only these foods did indeed lead to a complete resolution of my symptoms but after 1.5
00:00
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Max Gulhane MD
@MaxGulhaneMD
Jul 20, 2024
New podcast with Alexis Cowan, PhD We discuss the work of @DrJackKruse & foundations of decentralised medicine based on mitochondrial DNA, sunlight & circadian/quantum biology. Check it out 👇
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Max Gulhane MD
@MaxGulhaneMD
Jul 31, 2024
Prof. Michael Holick is a titan in the field of Vitamin D - having performed much of seminal research in the field In this interview - evolutionary biology of Vit D - skin cancer - POMC & sun addiction - dminder - Vit D guidelines & more CHECK IT OUT
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Max Gulhane MD
@MaxGulhaneMD
May 4, 2024
Sunlight has cardiovascular benefits that exceed the comparative risks of skin cancers in an all-cause mortality risk vs benefit formulation This isn't being communicated appropriately because subspeciality dermatology is not thinking about all cause mortality or CV death
21K
Max Gulhane MD
@MaxGulhaneMD
Oct 14, 2025
Circadian rhythm regulation should be first line lifestyle/behavioural advice for any patient with mental health disorder
⚡️ The Blue Light Diet ⚡️
@BlueLightDiet
Oct 13, 2025
What is the name of this journal? Nature Mental Health. To improve your mental health, get back to living how Nature says you should live. This means bright days and dark nights. This paragraph is ridiculous. "Greater night-time light exposure was associated with increased
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Max Gulhane MD
@MaxGulhaneMD
Oct 8, 2025
Key to mitochondrial rehabilitation is ‘gathering’ as many photons in early AM as possible Few
Dr Sam Soete
@sam_soete
Oct 8, 2025
Anatomy as Optics The body can be seen as a living optical system designed to distribute light intelligently. - The skin acts as a filter and diffuser. - The CSF serves as a light guide for the brain. - The blood vessels act as photon absorbers and transporters of NO-mediated
16K
Max Gulhane MD
@MaxGulhaneMD
Oct 18, 2025
This is what the data shows Your job is to understand the mechanism
Jonathan Jarecki
@Jonathanjarecki
Oct 16, 2025
Lung cancer Breast cancer colorectal cancer Ovarian cancer Endometrial cancer Renal cancer Bladder cancer Pancreatic cancer Brain cancer Leukemia Type 1 diabetes ALL are linked to SUNLIGHT exposure. Higher Latitudes (less UVB) = Higher Cancer Rates
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Max Gulhane MD
@MaxGulhaneMD
May 10, 2025
Does UV light cause DNA damage? Short answer is yes. But the full story is much more nuanced. Prof Michael Holick explains 👇 "A study by Felton et al. [96] provided a more realistic insight regarding sun exposure and its beneﬁcial and negative health consequences. They
49K
Max Gulhane MD
@MaxGulhaneMD
Nov 3, 2024
"The circadian timing system synchronizes clocks across the entire body to adapt and optimize physiology to changes in our environment. Light is received by specialized melanopsin-producing photoreceptive retinal ganglion cells (ipRGCs) in the eye. These ipRGCs project through
16K
Max Gulhane MD
@MaxGulhaneMD
Oct 15, 2025
High altitude, cold-temperature sun bathing was used extremely effectively in the treatment of tuberculosis This approach was particularly useful for ‘surgical’ or extra pulmonary TB, involving tuberculous infiltration of joints and limbs for which surgery was disfiguring and
9.6K
Max Gulhane MD
@MaxGulhaneMD
Sep 28, 2025
On the chomophore properties of the mitochondrial electron transport chain complexes "Complex I absorbs UV/ blue light by heme P450, resulting in a very high rate (up to 14 times) of mitochondrial ROS generation because it is the main site of ROS production within ETC. This
30K
Max Gulhane MD
@MaxGulhaneMD
Nov 16, 2024
The study shows that the vitamin D3 content of egg yolk was three- to fourfold higher in the groups that were exposed to sunlight (outdoor and indoor/outdoor groups) compared with the indoor group (P < 0.001). In contrast, free-range eggs randomly acquired from supermarkets had
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