Art Schuermans (@artschuermans) / X

Art Schuermans

1,008 posts

Art Schuermans

@artschuermans

Researcher @broadinstitute. Medical student @KU_Leuven. Cardiovascular sciences, pregnancy complications, aging-related disease mechanisms, and multi-omics.

België

Joined August 2017

Pinned
Art Schuermans
@artschuermans
Nov 21, 2024
What does the circulating proteome teach us about common heart diseases? Thrilled to share our analysis identifying new biomarkers, drug targets, and prediction models for these conditions. Co-led by @APournamdari, with @mchonig and @pnatarajanmd nature.com/articles/s4416… (1/x)
33K
Art Schuermans
@artschuermans
Jan 3, 2024
Thrilled to share our latest study @JAMACardio, where we identified 6 biomarkers w/ potential causal roles in hypertensive disorders of pregnancy doi.org/10.1001/jamaca… Grateful to everyone who contributed, especially mentor suprême @mchonig! Check out his thread below:
Michael Honigberg, MD, MPP
@mchonig
Jan 3, 2024
Excited to share our study led by @artschuermans out now in @JAMACardio Tools to prevent + treat hypertensive disorders of 🤰 remain limited Can Mendelian randomization (MR) reveal new causal biomarkers of preeclampsia & gestational HTN? jamanetwork.com/journals/jamac… 🧵👇 (1/X)
jamanetwork.com
Genetic Associations of Circulating Cardiovascular Proteins With Gestational Hypertension and...
This genetic association study investigates if mendelian randomization can identify associations between circulating cardiovascular disease–related proteins and hypertensive disorders of pregnancy.
17K
Art Schuermans
@artschuermans
Jan 14, 2023
Excited to share our work @Heart_BMJ on exercise training in patients w/ repaired tetralogy of Fallot! Mild- to moderate-intensity exercise interventions can improve exercise tolerance without evidence of adverse events or remodelling. Read it here: heart.bmj.com/content/early/…
9.8K
Art Schuermans
@artschuermans
Jan 25, 2024
Thrilled to see our work out in @JAMANetworkOpen! In 8,090 people from 2 cohorts, TET2-driven clonal hematopoiesis was - perhaps somewhat unexpectedly - associated w/ a stronger effect on incident HFpEF than HFrEF jamanetwork.com/journals/jaman… Definitely check out @mchonig's thread:
Michael Honigberg, MD, MPP
@mchonig
Jan 25, 2024
Now out in @JAMANetworkOpen , @artschuermans and I w/ Alex Reiner @fredhutch examine the role of clonal hematopoiesis of indeterminate potential (CHIP) 🩸🧬 in future/incident development of heart failure and its subtypes (HFpEF and HFrEF) jamanetwork.com/journals/jaman… 👇 (1/X)
jamanetwork.com
Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction
This cohort study evaluates the potential associations of clonal hematopoiesis of indeterminate potential (CHIP) and key gene-specific CHIP subtypes with incident heart failure with preserved and...
9.6K
Art Schuermans
@artschuermans
May 16, 2023
Excited to share that our study on CHIP in individuals with ASCVD, co-led by @esradgumuser, is out in @JACCJournals! Read the paper here: doi.org/10.1016/j.jacc… Don't miss @mchonig's thread below!
Michael Honigberg, MD, MPP
@mchonig
May 15, 2023
Our new paper in @JACCJournals #JACC led by @esradgumuser + @artschuermans examines the relevance of clonal hematopoiesis of indeterminate potential (CHIP) 🩸🧬 in indivs w/ established ASCVD jacc.org/doi/10.1016/j.… Short thread 👇 (1/6)
13K
Art Schuermans
@artschuermans
Nov 11, 2023
Thrilled to see our publication on CHIP and arrhythmias now in @ehj_ed! Thanks to all co-authors and everyone who helped make this possible 🙏 doi.org/10.1093/eurhea…
Michael Honigberg, MD, MPP
@mchonig
Nov 11, 2023
Sim pub w/ #AHA23 @AHAScience from @artschuermans now in @ESCJournals @ehj_ed #EHJ Does clonal hematopoiesis of indeterminate potential #CHIP predispose to cardiac 🫀arrhythmias ⚡️? academic.oup.com/eurheartj/adva… 👇 (1/8)
6.9K
Art Schuermans
@artschuermans
Jun 27, 2023
Meta-analysis of AVR in children reveals suboptimal results across substitutes, though the Ross procedure yields better survival vs. mechanical AVR. Proud to have contributed to this awesome study led by @MLNotenboom, out now in @ehj_ed! Read it here: doi.org/10.1093/eurhea…
4K
Art Schuermans
@artschuermans
Jun 22, 2023
Excited to share that our paper on birth weight, clonal hematopoiesis of indeterminate potential (CHIP), and CVD is now out @JAHA_AHA - see thread below a brief summary! (1/8) Open access link: ahajournals.org/doi/10.1161/JA…
7.8K
Art Schuermans
@artschuermans
Jan 16, 2024
Human data suggest that people w/ TET2 CH and high CVD risk may derive particular benefit from drugs that inhibit IL-1β, though mechanisms remain unclear. New study highlights a potential role for fibroblast-like cell accumulation and plaque stabilization nature.com/articles/s4416…
5.8K
Art Schuermans
@artschuermans
Jan 15, 2024
New study indicates that Lp(a) has a much stronger effect on coronary artery disease risk (per particle) than LDL, emphasizing Lp(a)'s potential as a target for cardiovascular prevention jacc.org/doi/10.1016/j.… @JACCJournals @EliasBjornson
3.8K
Art Schuermans
@artschuermans
Feb 1, 2022
Our new review with @DrAJLewandowski published in @AnatRecord is out! We aimed to describe the functional and structural characteristics of the preterm heart... (👇🏼) anatomypubs.onlinelibrary.wiley.com/doi/10.1002/ar…
Art Schuermans
@artschuermans
Jan 19, 2024
Awesome new study @NatureComms suggests a mechanistic role for fibroblast activation and cardiac fibrosis in the association of DNMT3A-driven clonal hematopoiesis with heart failure @shumliakivska @gluxan @StefanieDimmel1
3.8K
Art Schuermans
@artschuermans
Jan 28, 2024
New review @NatRevCardiol discusses the cardiovascular effects of immune checkpoint inhibitors and proposes modulation of immune checkpoint signaling as a therapeutic target for heart failure nature.com/articles/s4156…
3.5K
Art Schuermans
@artschuermans
Jan 18, 2022
Extremely excited to present our recent - and my first (!) - publication on biomarkers of AKI after pediatric cardiac surgery in @EurJPediatrics: link.springer.com/article/10.100… Many thanks to co-first author @JefVandenEynde and prof. Djalila Mekahli for their mentorship and support! 👇🏼