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Excited to share what I’ve been working on @arcinstitute!
STATE is a transformer-based model trained to predict how cells respond to perturbations, using the largest single-cell perturbation dataset to date: 170M observational and 100M+ perturbational cells across 70 cell lines.
Today @arcinstitute releases State, our first perturbation prediction AI model and an important step towards our goal of a virtual cell
State is designed to learn how to shift cells between states (e.g. “diseased” to “healthy”) using drugs, cytokines, or genetic perturbations
