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Today in @ScienceMagazine, we report a new DNA editing technology to seamlessly write massive changes into the right place in the human genome.
The reason gene editing hasn't transformed human health is that current gene editing technologies like CRISPR are very limited.
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What if we could universally recombine, insert, delete, or invert any two pieces of DNA?
In back-to-back @Nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design











