Institute for Protein Design (@UWproteindesign) / X

Institute for Protein Design

2,919 posts

Institute for Protein Design

@UWproteindesign

We create proteins that solve challenges in medicine, technology & sustainability 🟡 2024 Nobel in Chemistry 📍@UWMedicine — ipd.uw.edu/join-us/

Seattle, WA

ipd.uw.edu

Joined September 2013

Institute for Protein Design
@UWproteindesign
Mar 30, 2023
Today we're making RF Diffusion, our guided diffusion model for protein design with potential applications in medicine, vaccines & advanced materials, free to use. The software has proven much faster and more capable than prior protein design tools. bakerlab.org/2023/03/30/rf-…
GIF
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Institute for Protein Design
@UWproteindesign
Feb 22, 2023
01. Today we report the computational design of highly efficient enzymes. Lab testing confirms that these novel luciferases can recognize specific synthetic substrates and efficiently catalyze the emission of light. nature.com/articles/s4158…
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Institute for Protein Design
@UWproteindesign
Nov 11, 2021
(1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from DNA repair to membrane trafficking. science.org/doi/10.1126/sc… This work builds on breakthroughs in coevolution & deep learning (#Alphafold, #RoseTTAFold).
Institute for Protein Design
@UWproteindesign
May 11, 2023
Generative AI for protein design is now one click away. We've launched a new platform that puts powerful tools behind a simple web interface, making #proteindesign accessible to anyone. Try it here ➡️ huggingface.co/spaces/merle/P… Learn more on YouTube ➡️ youtu.be/bS71K2U0amA
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Institute for Protein Design
@UWproteindesign
Mar 24, 2022
Design of protein binding proteins from target structure alone | @Nature Our approach now enables targeted design of binders to sites of interest on a wide variety of proteins for therapeutic and diagnostic applications. #proteindesign nature.com/articles/s4158…
Institute for Protein Design
@UWproteindesign
Oct 9, 2024
Nobel Laureate David Baker on the phone with fellow awardees Demis Hassabis and John Jumper. The trio discussed how their teams have inspired one another and what the future may hold.
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Institute for Protein Design
@UWproteindesign
Jun 20, 2023
Congrats to David Baker who, together with Demis Hassabis & John Jumper, just received the Frontier of Knowledge Award in Biology & Biomedicine. "[Our progress is] the result of many hundreds of brilliant minds all working together. This award is as much theirs as it is mine."
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Institute for Protein Design
@UWproteindesign
Apr 5, 2023
Today we report the design of proteins that bind to disordered targets. This design strategy focuses on features common to the peptide backbone and can be used to generate binders for disordered proteins. nature.com/articles/s4158…
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Institute for Protein Design
@UWproteindesign
Sep 24, 2024
Stay tuned 🎧
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Institute for Protein Design
@UWproteindesign
Aug 17, 2023
Scientists in the Baker Lab have designed new proteins that change shape upon binding a target molecule. This research opens the door to new applications in drug delivery, environmental sensing & more. @FloPraetorius, @definitelyphil
Switch-like proteins inspired by transistors • Baker Lab
From bakerlab.org
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Institute for Protein Design
@UWproteindesign
Nov 30, 2020
“This really is a big deal” — David Baker on today's #AlphaFold news. From our team to @DeepMind: Congratulations! You have electrified this important field. We look forward to what can be accomplished in the coming years.
DeepMind’s protein-folding AI has solved a 50-year-old grand challenge of biology
From technologyreview.com
Institute for Protein Design
@UWproteindesign
Sep 10, 2020
Congratulations to our director, David Baker, on winning a Breakthrough Prize in Life Sciences! forbes.com/sites/alexknap…
Institute for Protein Design
@UWproteindesign
Apr 20, 2023
Today we report the use of reinforcement learning, a strategy used to solve games like chess and Go, to a challenge in protein design. This milestone in using #AI for science may enable more effective cancer treatments & new biodegradable textiles. science.org/doi/10.1126/sc…
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Institute for Protein Design
@UWproteindesign
Oct 10, 2024
As researchers, innovators, and communities worldwide celebrate this remarkable achievement, we look forward to the groundbreaking discoveries and life-changing solutions that still lie ahead—solutions made possible by the visionary work that has earned David Baker a Nobel Prize.
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