Li Tang (@Tang_Lab

Li Tang

413 posts

Li Tang

@Tang_Lab_EPFL

#Immunoengineering for better therapies | Associate Prof. of BioE @EPFL | Associate Editor @ESMO_IOTECH | Co-founder of @LemanBiotech

Lausanne, Switzerland

epfl.ch/labs/tang-lab/

Joined May 2021

Pinned
Li Tang
@Tang_Lab_EPFL
Oct 7, 2024
Thrilled to share our back-to-back two Nature @Nature papers on the unexpected role of type 2 immunity against cancer. We found that interleukin 4 (Fc–IL-4), a type 2 cytokine, reinvigorates exhausted T cells to potentiate anticancer immunotherapy w/ @YugangGUO2 @RongFan8(1/11)
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Li Tang
@Tang_Lab_EPFL
Dec 7, 2021
Our lab's new paper (rdcu.be/cCL0H) is now out at @NatBME. We discovered that cancer cells lower their cortical stiffness, which impedes T cell-mediated cytotoxicity by decreasing T cell force at the immune synapse (doi.org/10.1038/s41551…) (1/)
Li Tang
@Tang_Lab_EPFL
Jan 4, 2024
Our lab's new paper (nature.com/articles/s4158…) is now out at @NatureBiotech. We discovered that IL-10-expressing CAR T cells resist T cell dysfunction and mediate durable clearance of solid tumors and metastases (rdcu.be/duW2h) (1/)
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Li Tang
@Tang_Lab_EPFL
Dec 9, 2022
ETH Board officially announced my promotion to Associate Professor yesterday. It has been great 6 yrs at EPFL. Thanks to my trainees, collaborators, mentors, colleagues, my family and friends. Look forward to a lot more!@EPFL_BioE,@EPFLEngineering,@EPFL_en
Li Tang
@Tang_Lab_EPFL
Dec 16, 2023
We are hiring! A full-time postdoctoral position in cancer immunotherapy and immunoengineering for an Innosuisse project is immediately available in the Tang lab (tang-lab.epfl.ch) at EPFL, Switzerland. pl contact me ([email protected]). pl spread the word. Thanks!
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Li Tang
@Tang_Lab_EPFL
Nov 12, 2024
We make it to the cover @NatureBiotech! the IL-10-CAR-T cells eradicate solid tumors! nature.com/articles/s4158… The IL-10-CD19-CAR-T cells have shown promising clinical results in several investigator initiated trials too. Stay tuned! #SOHC @myESMO @ASH_hematology
Nature Biotechnology
@NatureBiotech
Nov 12, 2024
The November issue is live nature.com/nbt/volumes/42… On our cover, Zhao et al. show that expressing IL-10 in CAR T cells improves their mitochondrial function and therapeutic efficacy in multiple solid-tumor models go.nature.com/3vh5Bdv
IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and...
From nature.com
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Li Tang
@Tang_Lab_EPFL
May 27, 2021
Our lab's new paper (rdcu.be/clkR2) on metabolic reprogramming of exhausted CD8+ T cells is now out at @natureimmunology, highlighted as a cover story! (1/7)
Li Tang
@Tang_Lab_EPFL
Sep 13, 2021
Our lab’s latest paper is now published in @ScienceAdvances! We developed a strategy that keeps therapeutic proteins inactive outside the tumor. The proteins only "switch on" in the tumor, thus protecting healthy tissues. (1/9) science.org/doi/10.1126/sc…
Li Tang
@Tang_Lab_EPFL
Jun 29, 2023
Leman Biotech, a spin-off of my lab at EPFL, has successfully treated the first patient using its metabolically enhanced CD19 CAR-T therapy. The patient has achieved complete remission (NCT05715606)@LemanBiotech @EPFL_BioE @EPFLEngineering @EPFL_en
linkedin.com
Leman Biotech's Novel CD19 CAR-T Shows Great Promise in Low-Dose Treatment of Patients with...
Leman Biotech is pleased to announce the successful treatment of the first patient with recurrent or refractory diffuse large B-cell lymphoma using our metabolically enhanced CD19 CAR-T therapy, Meta...
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Li Tang
@Tang_Lab_EPFL
Jan 17, 2024
Thrilled to receive this prestigious recognition bestowed upon me! My heartfelt thanks to the editors, committee members, and my nominator. Look forward to continuing to contribute to our @Biomaterials_ community and upholding the standards of excellence this award represents.
Ankur Singh
@Dr_ASingh
Jan 16, 2024
On behalf of @Biomaterials_ editors, we're pleased to announce Drs Antonios Mikos & Ali Khademhosseini as the winners of "Biomaterials Global Impact Award" & Drs Xin Zhao & Li Tang as the winners of "Biomaterials Award for Young Investigator". Congrats!!! sciencedirect.com/journal/biomat…
8.6K
Li Tang
@Tang_Lab_EPFL
Sep 21, 2021
We are looking to recruit a postdoc in cancer immunology. The position is immediately available. See details here epfl.ch/labs/tang-lab/. Please email me at [email protected]. Thanks a lot for RT!
Li Tang
@Tang_Lab_EPFL
Mar 1, 2023
Leman Biotech, a spin-off of my lab at @EPFL, launched an IIT clinical trial (NCT05715606) of a metabolism-enhanced CD19 CAR-T Cell in the treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma lemanbio.com.cn/en/news/103.ht…. @startupEPFL
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Li Tang
@Tang_Lab_EPFL
Jan 29, 2024
Hot off the press! Are you wondering how mechanics govern immune responses in the context of immunotherapy and vaccines? A nice review/perspective by my students, Lucia Bonati, Weilin Li @HatarakuTSaibou, together with the @GoetzJacky group!
Nature Nanotechnology
@NatureNano
Jan 29, 2024
New content online: Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases dlvr.it/T21h6R
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Li Tang
@Tang_Lab_EPFL
Aug 3, 2021
Honored to receive the CRI CLIP grant to develop a new adoptive T cell transfer therapy. This is actually the second time I am funded by CRI. The last time was a CRI Postdoc Fellowship. Really grateful! Thanks @CancerResearch
EPFL Research Office
@EPFL_ReO
Aug 3, 2021
Congratulations to Prof. Li Tang on his new CLIP grant from the Cancer Research Institute! The funded project will focus on adoptive T-cell transfer and was awarded based on its great potential for transfer to the clinic. Find out more: cancerresearch.org/scientists/cri…