Today our important study on air pollutants in the promotion of lung cancer has been published in @Nature led by @WillHilliam @LimEmilia @DrClareWeeden @SwantonLab ...Thread below🧵nature.com/articles/s4158…
Charles Swanton
5,800 posts
Charles Swanton
@CharlesSwanton
Cancer Evolution and Genome Instability, Lung Oncologist Air Pollution and Drug Resistance Fair Weather 🚴
- This is absolutely wild - nature (as in mother) never ceases to amaze nature.com/articles/s4155…
- ecDNA are rogue genetic material that amplify genes, contribute to treatment resistance and drive genomic heterogeneity. We report on the Origins and impact of extrachromosomal DNA today in @Nature nature.com/articles/s4158…
- 3rd day of COVID19 testing #crick fantastic team of scientists clinical virologists and clinician scientists in a London collaboration @uclh @CRUKresearch @hsl @uclcancer @TheCrick @ICR_London to serve clinical staff, the homeless and patients
- 1/24 - Can we decipher order from cancer genomes? Our new paper “Pervasive chromosomal instability and karyotype order in tumour evolution” comes out in Nature today: nature.com/articles/s4158… @BCRFcure @TheCrick @CRUKresearch @RosetreesT @uclcancer @SwantonLab @royalsociety
- What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24, out in @CD_AACR today rb.gy/q484j9 Tweetorial👇
- Why do some patients benefit less than others from precision cancer medicine? We are excited to share our paper "Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling” out in @NatureComms. nature.com/articles/s4146… 🧵
- Excited to share our recent @SwantonLab @NickyMcGranahan & @MariamJHanjani lab work on the genomic evolution of non-small cell lung cancer metastases in #TRACERx, out @Nature nature.com/articles/s4158… A quick thread [1/13]
- Amazing! cervical cancer in women offered the vaccine between the ages of 12 and 13 (now in 20s) 87% lower than in an unvaccinated population: importance of Prevention and Vaccines - @CRUKresearch congrats👍🍾 @petersasieni
- Excited to share our TRACERx nature publication on circulating tumor DNA (#ctDNA, #MRD) detection in resectable lung cancer led by @AbboshChris, @AFrankell, @juditkisistok, Thomas Harrison, Aaron Garnett, @nbirkbak and @NickyMcGranahan 👇👇👇 Tweetorial🧵 nature.com/articles/s4158…
- gd T cells in cancer: at the front lines. New from @SwantonLab and @HaydayLab out in @NatureCancer today: “A local human Vd1 T-cell population is associated with survival in nonsmall-cell lung cancer” led by @dr_yinwu, @CharlesSwanton & @HaydayLab: nature.com/articles/s4301… 1/12
- 1/11 Our study on subclonal immune evasion in non-small cell lung cancer has just been published in @Cancer_Cell
- Our paper describing the use of an ultrasensitive circulating tumour DNA detection assay to stratify #TRACERx patients with early-stage non-small cell lung cancer pre-operatively for clinical outcome is out today @NatureMedicine. Thread below 👇
- We're thrilled to share work on tumour evolution in 421 TRACERx lung cancer patients by @AFrankell @Michi_Dii @drmaiseb @LimEmilia @TakKarasaki @Ward__Sophie RajuVeeriah @ColliverEmma @AMIHuebner @abi_bunkum @ZaccaSimo @MariamJHanjani @NickyMcGranahan🧵⬇️
