This past quarter 3,336 companies raised over $267 billion which eclipsed every prior full year, save two of them (2021 and 2025), underscoring the extraordinary enthusiasm among venture capitalists for anything AI. Notwithstanding the frothy valuations and capital intensity of AI platform companies, one of the pleasant knock-on effects might be the surge in new company formation. While AI adoption may also foretell dramatic job losses, it does strongly suggest that with the proliferation of these capabilities it will be easier to be an entrepreneur.
New Business Applications

Source: Apollo
Just over the past twelve months the number of new business applications spiked from ~100,000 per month to ~140,000 per month (right hand axis, above). Notably, the onset of the pandemic and its short-lived recession six years ago pushed many to become entrepreneurial out of necessity. The forces are different now and the impact less dire and immediate, but the result may be similar.
Obviously, it is a complicated, confusing time, made more so by conflicting social media posts almost hourly from the Administration and the on-again, off-again war with Iran. While making short-term investment decisions is fraught with extreme risks now, there are important signals to watch. Unemployment rates are manageable and in line with a good economy. Inflation is only slightly elevated, even in light of the body blows delivered to the economy over the past year. Somewhat surprising, the NASDAQ Index is trading at levels that are below historic averages, which for many may be counterintuitive given frothy private market valuation multiples.
NASDAQ 100 Forward P/E Ratio

Source: Citadel Securities
The employment picture is more nuanced, exacerbated by the hostility directed at immigration. Currently the level of job vacancies is largely balanced with the level of unemployment. Early in the pandemic the number of unfilled jobs spiked labor inflation rates. The prospect of job losses, perhaps due to impact of AI-driven replacement capabilities, may serve to mute the impact on inflation. In fact, according to the Bureau of Labor Statistics the U.S. economy only added a net of 181,000 jobs in all of 2025. An analysis by Fortune estimated that the U.S. healthcare sector alone created 693,000 new jobs in 2025, and that were it not for healthcare, overall job growth would have been negative.
Vacancy to Unemployment Ratio

Source: Bureau of Labor Statistics, BofA Global Research
More specifically, the labor market for IT positions has turned decidedly negative. In March employment in the technology sector declined by 24% from March 2025, according to data from Challenger, Gray & Christmas, with an overall net IT job loss of 52,000 in 1Q26. Bureau of Labor Statistics data had IT unemployment at 3.9% at the end of 1Q26, up from 3.1% in 1Q25. Bank of America data highlights the rotation from payroll costs to increased expenditures on technology among U.S. small businesses – technology replacing labor.
Payments to Payroll vs. Technology Services

Source: Bank of America (percent change, 3-month rolling average)
The level of venture capital investment this past quarter was historic by any measure. The five largest investments totaled $195.6 billion of the $267.2 billion (73% of the total) and yet was only 0.1% of the deals closed. While one might credibly argue that the $122 billion OpenAI round is not a venture capital deal, undeniably the AI companies simply dominated this past quarter, capturing nearly 89% of all invested capital and represented 43% of all companies. Notwithstanding a level of “AI-washing” with how companies now describe themselves, Pitchbook estimated that in 1Q26 AI companies accounted for 45% of the $9.5 trillion value held by venture capital funds.
This level of activity somewhat obfuscates the continued decline in the absolute number of investments made at each stage, although the proportion of larger and later stage rounds continued to increase. This rotation highlights the concentration of capital behind fewer companies as well as the dramatic increase in late-stage company valuations. Across all sectors late-stage rounds averaged $47.6 million ($44.0 billion invested across 925 deals) in 1Q26 as compared to $24.8 million in 4Q25.
Quarterly Venture Capital Investment Activity

Source: Pitchbook
This is not just a U.S. phenomenon although the U.S. market carries much of the water. Globally, 1Q26 venture capital investment activity touched $300 billion in nearly 6,000 companies, according to Crunchbase data. Of this amount, $242 billion was invested in AI companies.
Global Venture Capital Investment Activity

Source: Crunchbase
An obvious implication of this level of concentrated investment activity is the restocking of the unicorn herd. In 1Q26 another 66 unicorns were minted bringing the total to 912 companies valued at $5.8 trillion based on the post-money valuations of the last round according to Pitchbook. While many choose to stay private and independent longer, many other scaled companies continue to struggle to exit.
This shines a bright light on a cruel irony: rarely has such a new technology generated so much investor interest and created so many valuable companies and yet exit activity remains frustratingly elusive. Notwithstanding that 1Q26 looks like a blow-out quarter for exits, the $347 billion includes the $250 billion combination of SpaceX with xAI, which was not really a liquidity event. Setting that transaction aside, the $97 billion of remaining exit activity continues the modest recovery seen over the last several quarters in total exits. The average transaction value (ex-xAI) in 1Q26 was nearly $300 million, which is appreciably greater than the $230 million in 4Q25.
Quarterly Exit Activity

Source: Pitchbook
Analysts are calling for the SpaceX IPO this year to be valued over $1.5 trillion (~55x 2026 revenues) – crazy for a company that was last valued at $350 billion just over a year ago. This event could well be followed by IPOs at OpenAI and Anthropic, among several other very significant private venture-backed companies. Much could still derail any or all of these liquidity events but there is cautious optimism that investors will start to see dramatic distributions unlocked later this year. Obviously, it will be unevenly felt at first but one should expect to see that fundraising prospects for the long tail of venture capital firms should improve.
Secondary transactions continue to come of age as a possible path to liquidity. Last year secondaries totaled $240 billion across all private asset classes according to Jeffries, which was a six-fold increase from 2015. To provide some context, the broader private capital industry is estimated to be $24 trillion.
Fundraising in 1Q26 totaled $47.8 billion across 172 funds (average fund size $278 million), which compares nicely to the $66.7 billion across 626 funds (average fund size of $107 million) in all of 2025. What this masks is again the extreme concentration of success for just several firms in 1Q26. In fact, just six funds accounted for $36.4 billion or more than three-quarters of the capital raised. Exclusive of these top six funds, the average fund size was $69 million. Of all the funds raised in 1Q26, only 29 were raised by first-time fund managers. Shockingly, the median fund size in 1Q26 was an extremely modest $15.3 million.
As a point of comparison, “hot money” institutional investors in this risk-off environment moved nearly $11 billion just in March alone from junk bond funds into investment grade bonds, a 24-fold increase from February according to JP Morgan.
In the current climate investment returns have been hard to come by. HFR, a leading hedge fund data provider, tallied industry performance in March to be -3.1%, the worst performance for hedge funds since March 2020 (admittedly, April 2026 may show some recovery in performance given the “TACO” phenomenon). For 1Q26, not surprisingly the best performing asset was the New York Mercantile Exchange (NYMEX) Heating Oil Index, which surged 96.3%; the top four performing assets were all oil related. Cocoa was in last place, generating a -45.6% return. Cambridge Associates recently released its most recent venture capital performance data (4Q25), which were 7.8% and 11.6% for early-stage and late-stage, respectively, which does not look too bad in comparison.
Investment activity in the healthcare technology sector continues to be both resilient and encouraging. According to Rock Health, $4.0 billion was invested in 110 companies in 1Q26, suggesting an annual pace of ~$16 billion in approximately 450 companies – or just 13% of the last OpenAI round. The average deal size of $36.7 million is nearly twice that of just two years ago. Although 1Q26 activity was slightly down from 4Q25 ($4.2 billion), it was up smartly from the $3.0 billion invested in 1Q25.
Digital Health Investment Activity

Source: Rock Health
An internal Flare Capital analysis of 1Q26 AI healthcare technology investments based on both Pitchbook and Rock Health data highlights an interesting market development. It certainly appears that early-stage round sizes are materially larger and being done at elevated valuations. Dilution in Seed and Series A rounds coalesced between 18 – 22% (which is obviously not how one should value a company but is an oft-cited benchmark nonetheless). In 1Q26, our data showed that for Seed rounds the average and median pre-money valuations were $20.7 million and $17.1 million, respectively. For Series A and B rounds average and median pre-money valuations spiked significantly to $96.4 million and $58.0 million, and $402.6 million and $459.8 million, respectively.
Arguably, the value creation curve historically has been more asymptotic for healthcare technology companies as it took a few years at the outset to establish product/market fit to confirm that the products or services lowered costs and/or increased revenues and/or improved outcomes. That dynamic seems to have changed as companies are raising more capital, sooner. The curve now appears more linear, up and to the right as product development timelines have compressed dramatically.
In 2023 healthcare became the fastest growing component in the personal consumption expenditure price index (PCE) and is now nearly 17% of the index. As of late 2025, healthcare accounted for more than 50% of the growth in PCE. Coupled with the growth in the healthcare labor force and aging U.S. population, healthcare costs continue to drive overall inflation. It is estimated that by 2030 there will be more Americans older than 65 than younger than 18 for the first time in the country’s history. Fortunately, Goldman Sachs analysts recently concluded that a 70-year-old today as the equivalent cognitive capacity of a 53-year-old in 2000.
All of this points to the extraordinary opportunity technology has to re-architect clinical and administrative workflows throughout healthcare, especially as AI can make the system less expensive, more effective. A recent study by Johns Hopkins estimates that 10% of Medicare Advantage enrollees will disenroll this year as insurers modify plan offerings due to costs, exacerbating issues of access. Already 14% of all ACA members have missed first premium payments in 1Q26. Notwithstanding that many healthcare providers are seeing improved operating margins through deployment of agentic AI technologies, anxiety is high over pending deep cuts to reimbursement rates, particularly for the Medicaid segment in 2027.
This is happening against the backdrop of the fiscal condition of the U.S. economy. Recent Congressional Budget Office estimates the federal deficit will be $1.9 trillion in 2026 or 5.8% of GDP, increasing to 6.7% in 2036. The trailing 50-year average was only 3.8%. The publicly held federal debt is projected to be 120% of GDP, up from 101% in 2026, eclipsing the all-time high of 106% in 1946. This deficit needs to be financed, which will run the risk of crowding out other investment opportunities and/or absorbing significant capital, likely to the detriment of other possible uses.
As Percent of U.S. GDP

Source: Congressional Budget Office
We hope you will join us for our next quarterly Expert Roundtable Series on June 9, 2026 at 12:00pm ET (register here). To stay connected, subscribe here for the latest updates, news, and insights from Flare Capital Partners.

































































