CREATE TABLE `t` (
  `a` int(11) NOT NULL,
  `b` int(11) NOT NULL,
  `c` int(11) DEFAULT NULL,
  `d` int(11) DEFAULT NULL,
  `e` int(11) DEFAULT NULL,
  PRIMARY KEY (`a`,`b`),
  UNIQUE KEY `b` (`b`,`c`,`d`)
) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_bin
PARTITION BY RANGE ( `b` ) (
  PARTITION p0 VALUES LESS THAN (4),
  PARTITION p1 VALUES LESS THAN (7),
  PARTITION p2 VALUES LESS THAN (11)
) ;

insert into t values (1,2,3,4,5);
insert into t values (1,2,3,4,5),(6,2,3,4,6) on duplicate key update e = e + values(e);

mysql> select * from t;
+---+---+------+------+------+
| a | b | c    | d    | e    |
+---+---+------+------+------+
| 1 | 2 |    3 |    4 |   16 |
+---+---+------+------+------+
1 row in set (0.00 sec)

mysql> select * from t;
+---+---+------+------+------+
| a | b | c    | d    | e    |
+---+---+------+------+------+
| 1 | 2 |    3 |    4 |   11 |
+---+---+------+------+------+
1 row in set (0.00 sec)