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Reflections and Hope From Antarctica
March 26, 2026

Reflections and Hope From Antarctica

As many of you know, my wife and I recently had the incredible opportunity to visit Antarctica. It is difficult to adequately describe the experience of arriving in a place so vast, so pristine, and so profo…

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Alzheimer’s Prevention Strategies Validated
Top Researchers Reveal How Gluten Threatens Health
Food Choices Change Our Gene Expression
Alzheimer’s and Autism – Two Sides of the Same Coin
March 24, 2026

Alzheimer’s and Autism – Two Sides of the Same Coin

At first glance, autism and Alzheimer’s disease appear to exist at opposite ends of the neurological spectrum, one a condition of early brain development, the other a disease of later-life degeneration. But …
Breathing CO2 to Boost Brain Detox? What the Latest Study Reveals
March 10, 2026

Breathing CO2 to Boost Brain Detox? What the Latest Study Reveals

A fascinating new study explores a topic I have written about many times before: the brain’s waste clearance system, known as the glymphatic system. As I have discussed in previous blogs, one of the most imp…
Cheese Consumption Linked to Lower Dementia Risk
March 5, 2026

Cheese Consumption Linked to Lower Dementia Risk

A 25-year prospective analysis from the Malmö Diet and Cancer cohort evaluated the associations between high-fat and low-fat dairy intake and incident dementia in 27,670 Swedish adults. Dietary assessment co…
Can the Mediterranean Diet Help Prevent Stroke in Women?
February 26, 2026

Can the Mediterranean Diet Help Prevent Stroke in Women?

A recent meta-analysis published in Neurology offers encouraging news: women who closely follow a Mediterranean-style diet appear to have about a 12 percent lower risk of stroke. That finding is important…
Coffee and Dementia Risk Reduction
February 24, 2026

Coffee and Dementia Risk Reduction

A major new study published in JAMA followed more than 131,000 men and women for up to 43 years and offers reassuring news for coffee drinkers. Researchers looked at long-term consumption of caffeinated coff…
What the Nile Reveals About Modern Metabolic Health
February 20, 2026

What the Nile Reveals About Modern Metabolic Health

I’m writing this blog while cruising south (upstream) on the Nile River, watching the shoreline drift by in its slow, ancient rhythm. It is impossible to be here and not feel the weight of history. This rive…
Dr. Perlmutter’s Views on the 2025–2030 Dietary Guidelines for Americans
January 14, 2026

Dr. Perlmutter’s Views on the 2025–2030 Dietary Guidelines for Americans

For decades, federal dietary guidance has struggled to keep pace with what clinicians and researchers have observed on the front lines of chronic disease. The newly released Dietary Guidelines for Americans,…
Why Berberine Earned a Place in My Daily Supplement Stack
January 12, 2026

Why Berberine Earned a Place in My Daily Supplement Stack

When people ask me about supplements, I always come back to one foundational principle: if it doesn’t meaningfully improve metabolic health, it probably doesn’t belong in my routine. That’s exactly why berbe…
The Brain’s Immune System and a Breakthrough That Changes Everything
December 23, 2025

The Brain’s Immune System and a Breakthrough That Changes Everything

In my recent lectures, podcasts, and blog posts, I’ve been emphasizing a message that is still surprisingly new to many people: the health of the brain is inseparable from the health of its immune system. At…
Why Redefining Alzheimer’s as a “Biological” Condition Is Harmful, and Why the International Working Group Is Pushing Back
December 3, 2025

Why Redefining Alzheimer’s as a “Biological” Condition Is Harmful, and Why the International Working Group Is Pushing Back

In late 2024, the Alzheimer’s Association (AA) introduced new diagnostic criteria suggesting that Alzheimer’s disease can be identified in people who are completely cognitively normal, solely on the basis of…