1 in 3 COVID-19 survivors may develop a neuropsychiatric or neurological condition within 6 months.
From anosmia to strokes, the virus can leave lasting effects on the brain.
Research shows over 33% of post-COVID patients develop conditions like anxiety, depression, or
Psychiatry Excellence
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- Clinical trials reveal that some antidepressants are over 100% more effective than placebo, while others barely outperform it. The largest meta-analysis (Cipriani et al., 2018) compared 21 antidepressants in 116,477 patients, revealing striking differences in efficacy and
- Which antidepressants work most effectively, and which barely beat placebo? The largest meta-analysis (Cipriani et al., 2018) compared 21 antidepressants in 116,477 patients, revealing striking differences in efficacy and tolerability. Here’s how this data can transform your
- Did Freud predict the brain’s ‘hidden’ architecture? His model of the mind—Id, Ego, and Superego—was purely theoretical, but modern neuroscience suggests these structures have neurobiological correlates. Studies show that the Default Mode Network (DMN), Salience Network (SN),
- Pregabalin and gabapentin are widely prescribed for neuropathic pain and seizures Yet, their rising misuse potential and risks of dependency are raising alarms among clinicians Are we underestimating the dangers? Here’s an evidence-based guide to their mechanisms, clinical
- Sleep isn’t just “off.” The locus coeruleus (LC), the brain’s noradrenaline hub, stays active in a patterned way, shaping when we sleep deeply, dream, or wake too easily. (Osorio-Forero 2022) Here’s why it matters clinically. 1/11🧵
- ADHD isn’t just an “attention” problem. It’s impaired prefrontal regulation across distributed circuits (PFC–striatal–cerebellar–salience networks) that shape attention, inhibition, and emotion. Here’s how these circuits interact and what clinicians need to know about the
- Dissociation isn’t just a symptom – it’s a neurobiological survival mechanism. Research shows 30% of PTSD patients experience dissociation (Stein et al., 2013). The Polyvagal Theory (Porges, 2009) highlights the dorsal vagal complex as key in triggering shutdown when
- Up to 40% reduction in depression risk has been observed with adherence to anti-inflammatory diets like the Mediterranean diet, according to the PREDIMED study. Emerging research links dietary patterns to neuroinflammation, neurotransmitter synthesis, and gut–brain signalling.
- Why do some patients sleep 8–10 hours yet still wake exhausted? Because fatigue is not only about sleep duration, it reflects disrupted brain networks that leave the mind feeling foggy, unrefreshed, or in a state of hyperarousal. Here’s how to reframe fatigue clinically and
- Borderline Personality Disorder (BPD) isn’t just “emotion dysregulation.” It can be usefully conceptualised as a predictive-processing problem where salience, reward prediction errors (RPEs), and the endogenous opioid system (EOS) bias social learning. Here’s how clinicians can
- Did Freud anticipate the brain’s 'hidden' networks? His model of the Id, Ego, and Superego was theoretical, but modern neuroscience points to striking parallels. While Freud wasn’t describing brain networks, clinicians use his framework heuristically, with the Default Mode,
- 75% of anti-NMDA receptor encephalitis cases first present to psychiatrists—not neurologists. Could a manic or psychotic episode be an immune-mediated brain attack? Here’s what psychiatrists need to know about identifying and managing neuroinflammation. 🧵👇
- Cognitive symptoms in major depressive disorder (MDD) often persist even after mood improves, affecting memory, processing speed, and executive function. Vortioxetine has been investigated for its potential pro-cognitive effects, independent of its antidepressant properties














