Our new paper out today in Science. Wonderful team effort, showing the importance of innate immunity in the earliest stages of respiratory viral infection... please re-tweet!
Peter Openshaw
5,146 posts
Peter Openshaw
@p_openshaw
Mucosal immunologist and respiratory physician, working on lung infections (esp. COVID, RSV and influenza) at Imperial College London.
- Replying to @ArisKatzourakis and @BBCNewsI did a rapid response interview on the BBC news channel this morning to say that vaccine side effects very, very rare in comparison with the preventable risks of COVID-19. The staff seemed alarmed and embarrassed that they had given him the a platform.
- Covid: 150 deaths a day in UK an ‘unacceptably high number’, says professor channel4.com/news/covid-150… via @Channel4News
- I'm so pleased to get this award, which is actually a tribute to all fantastic people I've worked with and all those who have promoted immunology, collaboration and mutual kindness in science. Thank you all.We’re delighted that Prof Peter Openshaw, @p_openshaw, our past President, has been awarded a CBE in the #NewYearHonours in recognition of his services to Medicine & Immunology🎖️ All at the BSI send Peter our warm congratulations✨ Read more👇 immunology.org/news/past-bsi-…
- Particularly interesting is the comparison of the viral load by PCR (viral genome) vs. the virus that is infectious (by culture). There is no infectious virus beyond day 8; RNA can be found long after and is also found in stool. Importantly, there is no live virus in stool.Important new paper showing sites of #COVID19 viral shedding and timing vs. symptoms. Mainly throat and lungs, with very high virus titers, and seroconversion after 7 days. Also in GI tract. Throat swabs likely sufficient for testing. rdcu.be/b3lzn
- What a great start to the day. Just think what this could mean. Feel the grin widen and think of the suffering this might prevent. Science is just great.Today, we shared positive pre-clinical data demonstrating our ability to combine 6 mRNAs against 3 different respiratory viruses in 1 vaccine: COVID-19 booster + Flu booster + RSV booster. #mRNA
- Roche: 'we will provide tocilizumab for free during the emergency, the only limit will be our need to maintain supplies for those patients using it to treat other pathologies.'Roche: “fornire gratuitamente per il periodo dell’emergenza” il farmaco tocilizumab (RoActemra), con l’unico limite del mantenimento delle scorte necessarie per continuare a trattare quei pazienti che già fanno uso del medicinale per curare altre patologie."
- While adenovirus 41 is a possible underlying cause, it does not fully explain the clinical picture. Infection with this adenovirus has not previously been linked to such a clinical presentation.🆕 @WHO Disease Outbreak News: Multi-Country – Acute, severe hepatitis of unknown origin in children As of 21 April, 169 cases (aged 1 month to 16 years old) reported in 🇬🇧 🇪🇸 🇮🇱 🇺🇸 🇩🇰 🇮🇪 🇳🇱 🇮🇹 🇳🇴 🇫🇷 🇷🇴 🇧🇪. More info 👇 who.int/emergencies/di…
- Replying to @PeteUK7 and @danwalker9999To be clear, I'm not advocating getting repeated infections as a way to build up immunity, and strongly believe that vaccination and avoiding infection is the preferred way to protect against illness.
- Such an important message. We should have said it louder, with more certainty and right at the start. I'm sorry I didn't do that.It was wrong to believe that 'saving the economy' was an alternative to 'saving people's lives’. If anything it is the other way around and the two goals go together so that countries that kept the health impact of the pandemic lower suffered smaller economic consequences.
- "So, is COVID-19 vaccination safe during pregnancy? The data so far suggest that it is and, given the increased risks associated with COVID-19 in pregnancy, many pregnant people have decided to accept the vaccine."NEW Comment article by @VikiLovesFACS @imperialcollege 'Are COVID-19 vaccines safe in pregnancy?' go.nature.com/3sLIYHI
- Very interesting. Perhaps Omicron has developed a preference for ciliated epithelial cells like those in the nose, trachea, bronchus etc. and is getting better adapted to those areas (like RSV). This just compared ciliated bronchus to lung tissue.
Very interesting analyses about the virology of #Omicron, which may explain the faster spread of this variant. According to a new lab study, Omicron infects & multiplies ~70x faster than the Delta variant and the wild type SARS-CoV-2 in the human bronchus, but not in the lung. - mRNA-1345 vaccine against RSV based on prefusion F glycoprotein expression. mRNA-1345 uses the same lipid nanoparticle (LNP) as Moderna’s authorized COVID-19 vaccine and contains optimized protein and codon sequences.Moderna Receives FDA Fast Track Designation for Respiratory Syncytial Virus (RSV) Vaccine (mRNA-1345) - Yahoo Finance finance.yahoo.com/news/moderna-r…
