user avatar
Ziad Obermeyer
@oziadias
Physician + prof @UCBerkeley. Co-founder, @NightingaleOS, @Dandelion_AI4H. Machine learning, health, emergencies, espresso.
Berkeley, CA
Joined March 2013
Posts
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    Imagine testing everyone for COVID, every day. Sure it’d be expensive—but we’d diagnose infections in real time, and keep everyone else safe. We think we have a way to make this possible… at <$5/person/day. A thread on our new working paper: tinyurl.com/ydz664ju
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    Medical puzzle: Take Black vs. White patients with similar knee x-rays Why do Black patients have more pain? Our paper in @NatureMedicine provides one answer: go.nature.com/3i6zAuc Algorithms see causes of knee pain in Black patients, that human radiologists miss. 🧵
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    Ever wonder why your insurer charges a copay for statins (and other high-value meds)? Don’t they want to prevent heart attacks, strokes, etc? Copays never made sense to me. In this new paper in @QJEHarvard, we show copays kill. 🧵 tinyurl.com/nhk4v93f
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    Is this patient having a heart attack? After 10+ years in the ER, it’s still an agonizing question for me I turned the angst into a long paper with @m_sendhil in @QJEHarvarddoi.org/10.1093/qje/qj… Tl;dr—machine learning can have *huge* benefit, and help fix docs' errors 🧵
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    I spend a lot of “research” time pleading for access to health data @m_sendhil and I co-founded a new nonprofit, @NightingaleOS, so you don’t have to We link medical imaging data + ground truth outcomes, and make it available—free! Launching tomorrow at #NeurIPS2021
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    You can’t pick your doctor in the ER. But your doctor can pick you. Two implications: 1) A lot of "practice variation" may be *preference* variation 2) Don't assume "as-if-random assignment" to docs Thread on a new, short @JAMANetworkOpen paper tinyurl.com/w8bqqkj
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    Those of us building health AI products have a problem: Our algorithms look great—in our own data But how will they perform elsewhere? On other machines? On diverse patients? We’ve built a way to find out, at @Dandelion_AI4H: A free, public service for algorithm audits
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    Replying to @oziadias
    What if there were a different way to train the algorithm? L̵e̵a̵r̵n̵ ̵f̵r̵o̵m̵ ̵t̵h̵e̵ ̵r̵a̵d̵i̵o̵l̵o̵g̵i̵s̵t̵ Listen to the patient We train the algorithm to predict the *patient’s pain*, not the radiologist’s read
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    Your doctor sends you for a lab test. Ever wondered if the outside temperature on the day of the test changes its result? Neither did @devingpope or I… until we did this study! Turns out, temperature distorts results Thread—new paper in @MedCellPress
    Ambient temperature influences the results of some of the most used laboratory tests, and these distortions likely affect medical decision-making, including whether to prescribe medications. Read more in @MedCellPress here: cell.com/med/fulltext/S… @oziadias, @Devin_G_Pope
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    For the past 2 years, we’ve worked to diagnose and fix bias in dozens of algorithms. @caseymross wrote a wonderful piece about it today: statnews.com/2021/06/21/alg… And our bias ‘playbook’ distills the process into 4 simple steps: tinyurl.com/rnnhckz6 🧵
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    Just amazing news. And almost as amazing, Glaxo will sell it at just 5% above cost—huge value for the world. Science!
    WHO endorses world's 1st malaria vaccine. “I longed for the day that we would have an effective vaccine against this ancient and terrible disease,” said @DrTedros. “Today is that day. An historic day.” W @deniseroland wsj.com/articles/world… via @WSJ
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    We know communities of color suffer most from COVID-19. The way we’re allocating $175b in relief funding is also biased against them. Thread on our new paper, led by superstar @pragyakakani (supporting roles: @amitabhchandra2, @m_sendhil, me) jamanetwork.com/journals/jama/…
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    Like the rest of the scientific community, I am profoundly shocked and saddened by this news of another epidemiological association driven by unmeasured confounding. Thoughts and prayers and also we’ll keep running the same regressions (Yes this is a joke)
    It now seems safe to conclude that many prior epidemiological associations between #vitaminD deficiency and adverse health outcomes were driven by unmeasured residual confounding or reverse causality ja.ma/33vpaMz #KidneyWk
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    Replying to @oziadias
    3) Patients at the *highest risk* of drug-preventable events (e.g. heart attack)… …are *most* likely to stop the drug when they run out of money. This is not what simplistic economic models would predict—these patients should be the *most* willing to pay for the drugs.