Enjoy our ‘Proteome Landscape of the Kingdoms of Life’ @Nature. We analyzed 100 species by #proteomics #automation #µpac #AI and doubled the number of experimentally verified proteins.
nature.com/articles/s4158…
Matthias Mann Lab
722 posts
Matthias Mann Lab
@labs_mann
The Mann Lab is a pioneer in mass spectrometry-based proteomics. Tweets represent personal views from lab members and Matthias Mann @MPI_Biochem and @UCPH_CPR.
- We developed a scalable, quantitative and ultra-high sensitivity workflow for true single cell proteome analysis - one by one. Single cells have a stable proteome but not transcriptome. Great collaboration with @bruker @EvosepBio @fabian_theis. Preprint: rb.gy/l4q32n
- Very proud to announce that Matthias Mann is the first German scientist to reach 300,000 citations. Thanks to all the collaborators, co-authors and readers for this extraordinary achievement. @labs_mann would like to extend their heartfelt congratulations to you Matthias!
- We are proud to announce that Matthias Mann is the first German scientist with over 250,000 citations!!! Your whole team congratulates you Matthias for this fantastic achievement for your life´s work. With many exciting projects in the pipeline, more citations will fly in!
GIF - Our beginner’s guide article on the basic concepts of #MassSpectrometry and #proteomics. We hope it helps describe MS-proteomics to new colleagues and interdisciplinary collaborators. It is #openaccess for ease of sharing! @PPPublishing
- Our mapping of the cellular protein #interactome with unprecedented depth is now published @Nature. Leaps in robust #proteomics and analytic workflows enabled us to perform over 4.000 pull-downs in yeast unraveling the social and structural aspects leveraging #alphafold multimer.
Protein interactions are the foundation of functional and healthy cells. We @labs_mann are proud that our work for mapping the cellular yeast #interactome on a global scale is now published @Nature. nature.com/articles/s4158… yeast-interactome.org #proteomics #massspectrometry - Our article on how to identify proteins from silver-stained gels by nanoelectrospray just topped 10,000 citations!!! Not bad for a paper that a member of the American Academy of Sciences thought ‘ridiculous’ to send to PNAS :) scholar.google.de/citations?user…
GIF - Marrying #microscopy and #digitalpathology with single cell type proteomics at last. We developed Deep Visual Proteomics integrating #Imaging #AI #LMD and #MassSpectrometry. Great team effort @NNFCPR, Peter Hovarth @hpke1980, @Prof_Lundberg, @MPI_Biochem bit.ly/3t3RxyK
- Tremendously sad day for Danish science as Novo Nordisk Foundation is closing its flagship protein research institute, arguably the best in the world. @UCPH_CPR has been a beacon of science and progress for years. Let's cherish the remaining years & strive to continue the legacy.
- China clearly sees the potential of proteomics and is about to place a gigantic bet on it; multi-billion dollar and 30 years!!! All the better for the advancement of science and health. We contributed to the white paper out now in @Nature
- All data of the ‘Proteome Landscape of the Kingdoms of Life’ @Nature are open access. We integrated 340,000 quantified proteins in a graph database of 8 mio nodes and 54 mio relationships - ready to be explored: proteomesoflife.org
- Our biomarker discovery study for liver disease is out in @NatureMedicine today! Plasma proteomics detects early stages of liver disease, outperforming established clinical tests. Great collaboration with @UCPH_CPR, @hustniu, @UniSouthDenmark, @FLASH_OUH nature.com/articles/s4159…
- Today, we open up our GitHub repository for AlphaPept, our brand new framework for open, fast, #Python-based next generation of #massspec #proteomics analysis. Check it out here: github.com/MannLabs/alpha…. @numba_jit, @nvidia, @streamlit, @CuPy_Team, @Omic_Era, @jeremyphoward
- Congratulations to Matthias from his lab members on receiving the Otto Warburg Medal today for his outstanding work in MS-based proteomics, raising the bar in biochemistry & mol. biology. #WellDeserved #science #MassSpectrometry #OttoWarburgPrize @GBM_eV @MPI_Biochem @UCPH_CPR
