I have an opening for a PhD student working on molecular biology of bacterial biofilms.
More info here: drescherlab.org/join.html
Knut Drescher
259 posts
Knut Drescher
@knutdrescher
I love science and discovering new things.
- I am recruiting for my new lab at the Biozentrum in Basel! Looking for postdocs and PhD students with a background in molecular microbiology, RNA, bioinformatics, or biophysics (one of these categories is fine...). Details here: drescherlab.org/join.html
- Bacterial biofilms form on human immune cells: how? Why? 👇 cell.com/cell/fulltext/… W/ @LuciaVidakovic @roi1avraham @alexpersat @MikhalevaSofya @HannahJeckel @KerstinMicrob
- I am so thrilled that this is really happening: our lab is moving to @biozentrum! I can't wait to get started. Big thanks to everyone involved in Basel, CH, and in Marburg!Two new professors appointed to @biozentrum @UniBasel_en: @knutdrescher studies biofilm formation and @AnissaKempf investigates how the brain controls sleep. A warm welcome to our new colleagues! >> bit.ly/34xjMvx
- Our software tool BiofilmQ for quantitative image analysis of microbial communities is now online: We wanted to create a tool for any community, any size, any image type, any analysis. I think BiofilmQ comes close to this aim.
- Our single-cell image analysis method for 3D bacterial biofilms is now out. 👇 Robust and versatile, based on deep learning. It even enables cell lineage tracking. It can be used as a basis for BiofilmQ analysis or your own custom analysis.
- Faculty opening: Assistant/Associate Professor in Molecular, Cellular or Systems Biology with broadly defined scope of topic. Location: my institute, @biozentrum in Basel. Deadline September 19. biozentrum.unibas.ch/open-positions…
- Interested in learning how to analyse images of microbial communities with BiofilmQ? Here are 3 hours of a hands-on tutorial session from the #BioImageAnalysis #I2K workshop - now on youtube: Intro: youtu.be/IWqyAHaiVLQ Examples: youtu.be/yn6JM78hfzQ
- We developed a method for spatiotemporal transcriptome measurements during bacterial swarm development, which revealed cross-feeding across generations! Now out: 👇How do microbial communities develop? Combining live-cell microscopy with a robotic arm for sampling reveals a cross-feeding mechanism during Bacillus subtilis swarm development. Congrats to @HannahJeckel @no_show3 @knutdrescher & colleagues! nature.com/articles/s4156…
- Interested in biofilm image analysis? We just released a major update to the BiofilmQ software, to integrate single-cell analysis capabilities. drescherlab.org/data/biofilmQ/… We also give 3 BiofilmQ workshops, as part of the online I2K conference i2kconference.org/workshops
- During biofilm dispersal, how do cells detach themselves from the matrix? We found: type IV pilus retraction releases cells. Adding in some matrix degradation clears the path for departure. This is necessary & sufficient for biofilm dispersal @pksjnu1 @DanielRode211 @papenfortlabVibrio cholerae biofilm dispersal regulator causes cell release from matrix through type IV pilus retraction biorxiv.org/cgi/content/sh… #biorxiv_micrbio
- Our #BiofilmQ software tool for biofilm image analysis is now available. It works for any spatially structured microbial community, enabling space-time analysis and biofilm phenotyping. Plenty of video tutorials + detailed documentation are available. Hopefully a useful resource!
- We developed a new light sheet confocal microscope, based on only a single high-resolution objective. Its perfect for single-cell imaging of biofilms with low phototoxicity. The design principle is a bit mind-bending, but I think its the future. Paper is out now 👇Thrilled to see my first first-author paper on light sheet microscopy published! We improved axial plane optical microscopy by implementing digital confocal slit scanning and carefull objective selection, the DC-APOM! (1/4) doi.org/10.1364/BOE.42…
- How do cells in biofilms respond to antibiotic stress? As a collection of individuals, or are there emergent community-level responses? Find out in mechanistic detail: our new paper in @NatureMicrobiol w/ @Fdiazpascual. Paper: rdcu.be/bVEdLCool @NatureMicrobiol from @knutdrescher lab Breakdown of Vibrio cholerae biofilm architecture induced by antibiotics disrupts community barrier function (w/ @TheThormannDen, Fitnat Yildiz, @CareyNadell, Jörn Dunkel, Hannes Link groups) nature.com/articles/s4156…
