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Marnix Jansen
@jansen_marnix
Computer vision in pathology, Professor of Pathology @UCLcancer and Consultant Histopathologist @UCLH. Londoner, father of 2.
London, England
cancerresearchuk.org/our-research/r…
Joined May 2015
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    Marnix Jansen
    @jansen_marnix
    Jul 3, 2024
    Hypermutator cancers are defined by increased mutation rates. But do mutation rates evolve with time during tumour growth?⏱️ In this work @NatureGenet we show that hypermutator cancers use an unexpected set of genetic gear switches to adapt mutation rates to immune selection.
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    Hamzeh Kay
    @hamkay02
    Jul 3, 2024
    How do mismatch repair-deficient (MMRd) cancers trade off the evolutionary costs and benefits of elevated mutation rates? Delighted to share our paper on adaptive mutability in MMRd colorectal cancer (CRC) @NatureGenet nature.com/articles/s4158… Tweetorial 🧵below
    20K
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    Marnix Jansen
    @jansen_marnix
    Dec 20, 2023
    Random story My dad passed away unexpectedly two weeks back. We had a private remembrance service last week. This morning a card arrived in the mail for the grandkids which my father sent days before passing and had been making its way here since then. Priceless. Thanks dad!
    83K
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    Marnix Jansen
    @jansen_marnix
    Oct 17, 2021
    - Yes OR 6? I'm calling in a frozen station 13. - Okay,..[crackle] ..tell us [crackle]. - Its not malignant. - Are you saying it's [crackle] malignant? - It's not malignant!! - (surgeon shouting across the floor) DID YOU SAY MALIGNANT?? - IT'S BENIGN!!! THERE AINT NO CANCER!!!
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    Marnix Jansen
    @jansen_marnix
    Aug 8, 2022
    Here's an odd 🐦 Microscopic colitis pattern, but you find rows of giant cells and macrophages have accumulated in the upper mucosal reaches. Normal colonoscopy, no medication, usual reason to investigate. What's going on? #GIpath
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    Marnix Jansen
    @jansen_marnix
    Feb 2, 2020
    Replying to @UtterlyInterest and @DannyDutch
    This is a fysiotherapist in Dartmouth Park
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    Marnix Jansen
    @jansen_marnix
    Aug 5, 2021
    Massively proud PI hugging freshly minted PhD Hamzeh Kayhanian who defended his PhD thesis today and passed with minor corrections. @uclcancer
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    Marnix Jansen
    @jansen_marnix
    Aug 31, 2021
    Think this would do for a collagenous colitis. #gipath
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    Marnix Jansen
    @jansen_marnix
    Mar 1, 2022
    Small adenoma in a young Lynch patient. The MMR proteins involved are MSH2 and MSH6. #GIpath
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    Marnix Jansen
    @jansen_marnix
    Oct 24, 2020
    Case for trainees. Urgent biopsies of a 3cm palpable mass on the anterior wall encroaching the dentate line. What do you tell the endoscopist?
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    Marnix Jansen
    @jansen_marnix
    Dec 12, 2020
    Hello cryptolytic granuloma my old friend
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    Marnix Jansen
    @jansen_marnix
    Dec 6, 2020
    EUS-FNB of a small paraduodenal lesion Which immunos are you ordering? Likely gene mutation? #GIpath
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    Marnix Jansen
    @jansen_marnix
    May 27, 2021
    We got married 8 years back with 20 guests. Turns out we were way ahead of the game. #ceremini
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    Marnix Jansen
    @jansen_marnix
    Aug 6, 2021
    Double heading with the new subspecialty trainee.
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    Marnix Jansen
    @jansen_marnix
    Feb 17, 2022
    10mm polyp upper body, otherwise normal endoscopy Your sign out? #GIpath