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Graham Collins
@graham74GC
Associate Professor of Haematology and lymphoma specialist at Oxford Cancer and Haematology centre. Christian, husband and father.
Opinions are mine
Joined December 2013
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  • user avatar
    Graham Collins
    @graham74GC
    Mar 5, 2020
    Just been through my clinic list for Tuesday. Out of 32, 21 suitable for telephone consult rather than face to face. Reduces risk to them and to others in hospital. (Also saves time, fuel, parking etc) This may change the way we work in the long term. #protectpatients #COVID19
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    Graham Collins
    @graham74GC
    Jun 27, 2023
    It’s been a while coming but the first CAR-T are being infused today @OUHospitals. Great team involved in set up and delivery of this groundbreaking treatment.
    27K
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    Graham Collins
    @graham74GC
    May 7, 2022
    Some good news for Saturday morning. Blood cancer survival rates rise faster than for other common cancer types. Data from 2010-2016. Most dramatic for myeloma.
  • user avatar
    Graham Collins
    @graham74GC
    Jun 14, 2022
    Really honoured to be awarded the position of Associate Professor of Haematology in the @RDMOxford of Oxford University. And along with such amazing colleagues like @shapiro_susie.
  • user avatar
    Graham Collins
    @graham74GC
    Sep 24, 2019
    Why haem is the best specialty: - most fascinating diseases (lymphoma, AML, TTP, Sickle) - most diverse treatments (ADCs, SCT, CAR-T, gene Rx) - most engaged and inspiring patients - most dynamic and committed teams Why would you do anything else? #haematologybestspecialty
  • user avatar
    Graham Collins
    @graham74GC
    Oct 31, 2022
    Why is alpha thalassaemia hard to understand? Because we have 4 alpha globin genes (2 from each parent). 1 gene deleted: trait (harmless) 2 genes deleted: trait (harmless) 3 genes deleted: HbH disease (thal intermedia - occ blood Tx) 4 genes deleted: in utero death (hydrops)
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    Graham Collins
    @graham74GC
    Apr 3, 2019
    #Hodgkin Lymphoma • unique history (Thomas Hodgkin) • unique demographic (TYA) • unique cancer cell (Reed-Sternberg) • unique microenv (exuberant inflammatory background) • unique sensitivity to treatment (RT, chemo and immunotherapy) #fascinatingdisease
  • user avatar
    Graham Collins
    @graham74GC
    Jul 15, 2020
    Important to remember that lymphoma is not a radiological diagnosis. Biopsy always needed. In the last few months in my practise ‘lymphoma’ on CT turned out to be: - sarcoid - metastatic renal Ca - glioblastoma - adenoCa of small bowel #alwaysgetabiopsy #lymsm
  • user avatar
    Graham Collins
    @graham74GC
    Jan 25, 2023
    Pola-R-CHP has been approved by NICE for front line treatment of DLBCL in IPI 2-5. This means hospitals in England are legally obliged to offer it so this will become a new standard. More thoughts in thread. #lymsm nice.org.uk/guidance/indev…
    65K
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    Graham Collins
    @graham74GC
    Apr 26, 2023
    With #ASCO23 and #ICML23 just around the corner we'll hear a lot about PD1 inhibition and #Hodgkin lymphoma. What's all the fuss about? Follow this thread to understand more.
    58K
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    Graham Collins
    @graham74GC
    Jul 6, 2022
    Time to stop doing marrows in follicular lymphoma? BM biopsy was irrelevant to accurate response assessment in 99% of trial subjects in this study. Further, if in imaging CR, no PFS diff if had BMBx to confirm. #lymsm
    ascopubs.org
    Relevance of Bone Marrow Biopsies for Response Assessment in US National Cancer Institute National...
    PURPOSEBone marrow biopsies (BMB) are performed before/after therapy to confirm complete response (CR) in patients with lymphoma on clinical trials. We sought to establish whether BMB add value in...
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    Graham Collins
    @graham74GC
    Nov 3, 2022
    #ASH22 abstracts are out! Number 001 is the Triangle trial: • RCHOP/RDHAP + ASCT vs • ibrutinib + RCHOP/RDHAP + ASCT & ibr Mx vs • above but no ASCT Result: looks like we don’t need ASCT in 1st CR in MCL when Ibr used. Great work from European MCL network! #lymsm
  • user avatar
    Graham Collins
    @graham74GC
    Nov 30, 2021
    ATLL in a tweet • HTLV1: test family • Types: smouldering, chronic, primary cut, lymphoma (>75% 🇬🇧 cases), acute • CD4/25+ ‘flower cells’, ⬆️ calcium • strongyloides co-infn: serology • AZT/IFN + CHOP if nodal • allo CR1 (incl raltegravir) • mogamulizumab for R/R #lymsm
  • user avatar
    Graham Collins
    @graham74GC
    Dec 6, 2021
    Once a year I teach on haemostasis. Every year my imposter syndrome grows a little more acute. Had to look up the name of the reversal agents of dabigatran and apixaban beforehand but still couldn't remember! Anyway - here's the summary. @nicola_curry.