Blake Byers (@byersblake) / X

Blake Byers

661 posts

Blake Byers

@byersblake

Cofounder @Newlimit to extend our lifespans. Investor in early stage founders — 10 IPOs and counting. @Stanford bioengineering PhD.

San Francisco, CA

Joined July 2011

Blake Byers
@byersblake
Dec 8, 2024
There are people who genetically only need 4-6 hrs of sleep per night. They also "tend to be more optimistic, more energetic and better multitaskers. They also have a higher pain threshold, don’t suffer from jet lag and some researchers believe they may even live longer." We
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Blake Byers
@byersblake
Sep 11, 2022
At Google Venture a decade ago we searched for AI enabled companies and came up dry. That has changed. AI is going to eat software companies. Primarily because it creates entire new UX that incumbents can’t adopt without breaking their product. 10 year hypercycle just started.
Blake Byers
@byersblake
Nov 22, 2024
For 20% of SF's public transit budget you could buy and run a fleet of 15,000 Waymos and let everyone ride for free. Thats enough to cover the entire ridership of SF's public bus system with much better service. Assumptions: -Conservative 12 year average life of the Waymo with
2.9M
Blake Byers
@byersblake
May 6, 2025
We’ve raised a $130 million Series B led by @kleinerperkins alongside new investors @natfriedman/@danielgross , @vkhosla, and @humancapital — joined by existing investors @foundersfund , @_DimensionCap, and @brian_armstrong (yes, the cofounders are doubling down). We also raised
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Blake Byers
@byersblake
Feb 3, 2025
I work on a longevity company. My cofounder and I committed $110M of our own money into the company. So you'd think I'm some longevity maximalist. But I don't actually take any drugs or supplements because I don't think anything available today has large enough effects for
208K
Blake Byers
@byersblake
Jan 28, 2025
A few friends and I are going to fund a $400k research study on whether we can get a taste of this superpower for everyone. We have some friends that run a gene editing lab at Harvard who are willing to run the experiments. Key points to validate: (1) Determine at what stage of
Blake Byers
@byersblake
Dec 8, 2024
There are people who genetically only need 4-6 hrs of sleep per night. They also "tend to be more optimistic, more energetic and better multitaskers. They also have a higher pain threshold, don’t suffer from jet lag and some researchers believe they may even live longer." We
136K
Blake Byers
@byersblake
Dec 12, 2021
One of the greatest projects humans can work on is to turn aging from inevitable to controllable. @brian_armstrong and I are cofounding NewLimit to uncover scientific truths and build products to extend all of our lives. Come join us.
blog.newlimit.com
Announcing NewLimit: a company built to extend human healthspan
Aging is something that affects all of us, yet there are only a couple organizations in the world that are applying industrial scale to investigating the aging process.
Blake Byers
@byersblake
Dec 23, 2024
Silicon Valley has flipped Wall Street for power in DC. Surprisingly, it happened with a Republican elect even though Democrats have held a massive majority in tech forever. This is a few years behind tech flipping Hollywood for cultural power but still much faster than I had
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Blake Byers
@byersblake
Jan 3, 2025
Replying to @brian_armstrong
Adjusting for purchasing power, China's GDP surpassed US in 2017. And you really do need to adjust for PPP.
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Blake Byers
@byersblake
Dec 8, 2024
Replying to @WillManidis
yep, it is. single point mutation too
78K
Blake Byers
@byersblake
Jul 22, 2025
Daniel Lurie is running a political masterclass. Majority approval rating across every major political group in the city. I would have thought this was ~impossible.
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Blake Byers
@byersblake
Sep 25, 2024
AI Bio trajectory. +2 years: AI instantaneously generating novel antibody drugs to known targets. Will take +5 years for ~any given drug composition. +6 years: AI improves target selection by 2X, defined by PTS. +10 years: AI doing ~all target selection. +20 years: AI helps
96K
Blake Byers
@byersblake
Oct 20, 2025
+$45M on a $1.62B cap note from @EliLillyandCo, Duke, Section 32 and others -- just five months after our Series B. Lilly is flirting with becoming an Aging Company. Excited to have them back @newlimit and for more companies to go after the most important human ailment.
209K
Blake Byers
@byersblake
Jul 18, 2025
NewLimit paper just dropped @icmlconf showing our SOTA AI models can predict perturbed cell states. Helps to have the largest primary cell perturbation dataset in the world. Bonus points for one of the first demonstration of active learning in bio.
196K