Wickstrom-Lab (@WickstromLab) / X

Wickstrom-Lab

1,891 posts

Wickstrom-Lab

@WickstromLab

Science & fun from the lab of Sara Wickström at the Max Planck Institute for Molecular Medicine & U of Helsinki. Stem cells and mechanical forces. Tweets by SW

Münster, Germany

mpi-muenster.mpg.de/660820/wickstr…

Joined December 2017

Pinned
Wickstrom-Lab
@WickstromLab
Sep 9, 2024
How do #stemcells integrate information to make fate decisions? Check out our latest preprint where we find that growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to determine whether to retain or exit #pluripotency🧵👇biorxiv.org/content/10.110…
34K
Wickstrom-Lab
@WickstromLab
Sep 16, 2022
We took on the challenge with @KateMiro1 to illustrate key aspects of #nuclear #mechanotransduction in a single #snapshot 👇Hope it’s useful! cell.com/cell/fulltext/…
Wickstrom-Lab
@WickstromLab
Nov 2, 2021
Excited about this new adventure and grateful for all the support that made it happen! The department of Cell and Tissue Dynamics will be recruiting on all levels, please contact me for opportunities in #stemcell #mechanobiology #morphogenesis and #cancer related topics
MPI Molecular Biomedicine
@MPI_Muenster
Nov 2, 2021
We are thrilled 🥳 to announce that Sara Wickström of the @Wickstromlab is appointed new director at the @MPI_Muenster 🎉 @maxplanckpress. Read our 📢📰ℹ️ press release: mpi-muenster.mpg.de/665175/2021110…
Wickstrom-Lab
@WickstromLab
Oct 28, 2024
Excited to share our latest work on an image analysis paradigm that combines cell state and morphology analyses of patient biopsies at single cell resolution to uncover clinically relevant head-and-neck #cancer phenotypes! @CellCellPress cell.com/cell/fulltext/… tweetorial👇
48K
Wickstrom-Lab
@WickstromLab
Jul 8, 2021
What happens to stem cells when we age? Our study on the role of mechanical properties of the niche on stem cell aging is out 🥳Matrix stiffening restricts chromatin accessibility and attenuates aged hair follicle stem cell functions 🧵. nature.com/articles/s4155…
Wickstrom-Lab
@WickstromLab
Apr 16, 2020
Excited to share our work on the impact of mechanical forces on the nucleus and chromatin @cellcellpress. In response to stretch chromatin and the nucleus soften to prevent DNA damage! a thread 1/x
Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced...
From cell.com
Wickstrom-Lab
@WickstromLab
Jan 6, 2022
We are looking for postdocs with biology, bioengineering or physics backgrounds to work on various aspects of stem cell fate regulation and nuclear mechanotransduction. Join us at @MPI_Muenster! mpi-muenster.mpg.de/679712/job_ful… or spread the word 🙏
Wickstrom-Lab
@WickstromLab
Dec 13, 2022
Our latest preprint💥 Tissue deformation is critical for organ generation, but how do complex organs consisting of multiple compartments and cell types achieve this? A fantastic interdisciplinary collab with @ManningResearch biorxiv.org/content/10.110… short🧵👇
biorxiv.org
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue...
Morphogenesis and cell state transitions must be coordinated in time and space to produce a functional tissue. An excellent paradigm to understand the coupling of these processes is mammalian hair...
Wickstrom-Lab
@WickstromLab
Sep 8, 2020
Excited to share our latest work, where we studied mechanisms of stem cell fate reversibility. We show that the ability of progenitors to go back into being stem cells requires metabolic reprogramming in the hair follicle. Out now @Cell_Metabolism cell.com/cell-metabolis… A🧵1/5
Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair...
From cell.com
Wickstrom-Lab
@WickstromLab
Jul 7, 2020
Honored to become a EMBO Member! A huge shout out of appreciation to all past and present lab members 😍 And congratulations to all new members, especially fellow #aging and #mechanobiologists @DMVlab @PCusachs @Equipe_lenne @NordenLab @amartinvill #thorstenhoppe -Sara
EMBO
@EMBO
Jul 7, 2020
52 Members and 11 Associate Members have been newly elected and join the community of the EMBO Membership. They boast a large range of accomplishments, with candidates elected based on scientific excellence and pioneering research. Read more at bit.ly/3gzmseS
Wickstrom-Lab
@WickstromLab
Aug 21, 2023
Incredibly honored and thankful to @ASCBiology and all past and current lab members whose hard work and dedication is behind all our discoveries @MPI_Muenster @helsinkiuni @STEMMProgram
American Society for Cell Biology
@ASCBiology
Aug 21, 2023
For her research innovation that significantly impacts progress in advancing the field of cell biology Sara Wickström of the Max Planck Institute for Molecular Biomedicine will receive ASCB’s Innovation in Research Award. Congratulations! @WickstromLab @MPI_Biochem
23K
Wickstrom-Lab
@WickstromLab
Feb 3, 2024
Very happy to see our preprint on epithelial mechanics in hair follicle morphogenesis now published nature.com/articles/s4155… . Congratulations @Clem_Villeneuve @alihashmiii @IreneYlivinkka and team! @STEMMProgram @MPI_Muenster @helsinkiuni For a tweetorial see 👇
Wickstrom-Lab
@WickstromLab
Dec 13, 2022
Our latest preprint💥 Tissue deformation is critical for organ generation, but how do complex organs consisting of multiple compartments and cell types achieve this? A fantastic interdisciplinary collab with @ManningResearch biorxiv.org/content/10.110… short🧵👇
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue...
From nature.com
31K
Wickstrom-Lab
@WickstromLab
Feb 9, 2022
Matrix and mechanobiology enthusiasts in Finland and elsewhere: join us for this free of charge online minisymposium March 24th! We will showcase young researchers, submit your abstract for a short talk or register to participate here sidekudostutkijat.fi/annual-meeting…
Wickstrom-Lab
@WickstromLab
Dec 4, 2022
Celebrating the amazing @priscaliberali winner of #embo gold medal 🥇 #CellBio2022 #ASCB2022 with a bunch of fun mechanobiologists 😀 @PCusachs @YanlanMao @KateMiro1 @suzanne_team