Our paper describing NEAT-seq, a method to simultaneously measure transcription factor protein abundance, ATAC-seq, and RNA-seq in single cells, is now out at Nature Methods! Congrats to Amy and Ben!
William J. Greenleaf
157 posts
William J. Greenleaf
@WJGreenleaf
Professor, Stanford University, Department of Genetics. Exploring the physical genome
- Excited to announce that our paper describing NEAT-seq, a method to simultaneously measure transcription factor protein abundance, ATAC-seq, and RNA-seq in single cells, is out on biorxiv! Congrats to Amy and Ben!
- Incredibly excited that our paper linking single molecule states of TF binding to gene expression using quantitative thermodynamic models is out in Nature today. An amazing collaboration with the Bintu Lab. Congrats to Ben, Michaela, and Julia!
- Our paper describing ArchR, a single cell analysis platform designed for scalable analysis of open chromatin data, is out in Nature Genetics. Congrats to Jeff and Ryan! nature.com/articles/s4158…
- Our work using single-molecule chromatin configurations to link TF binding to gene expression is now out on bioRxiv! Amazing effort from @bgrdoughty, @MichaelaThinks, and @juliaschaepe, and an immensely rewarding collaboration with the @BintuLab: biorxiv.org/content/10.110… [1/n]
- Our collaborative paper defining a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer is now out in Nature Genetics. Congrats to Winston, Stephanie, Mike, and all other co-authors!
- Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors!
- Spear-ATAC, a method for assaying open chromatin and Crispr guides, is out! Congrats to @Sarah_E_Pierce and @JeffreyGranja nature.com/articles/s4146…
- Our new paper on multiomic single cell analysis of leukemia is out in Nature Biotech: nature.com/articles/s4158…. Congrats to Jeff, Sandy, Lisa, and all co-authors!
- Our single cell ATAC-seq analysis of the human hematopoietic tree is out in Cell!
- We are drowning in amazing data! My lab is looking for motivated and talented postdoctoral fellows excited about using large-scale, single cell multi-"omic" data sets to explore gene regulation in human development and disease! Please reach out if interested!
- Our paper using single molecule sequencing to map long range chromatin accessibility is out in Nature Methods! Congrats to Georgi and Zohar!
- Very happy to announce the release of ArchR, our comprehensive and scalable software package for single-cell chromatin accessibility analysis! Try it now! And congrats to Jeff and Ryan!
