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Vincent Rajkumar
@VincentRK
Editor-in-Chief, Blood Cancer Journal; Chairman @IMFmyeloma Board; Cancer & Myeloma Research; Opinions solely personal views bit.ly/3f4TnJl
Rochester, MN, USA
Joined March 2009
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    I would like to share the story of how a patient with cancer came up with the idea for a randomized trial, & how listening to him saved a lot of lives. 1/ In 2002, I had just completed a randomized trial with the notorious drug thalidomide for the cancer, multiple myeloma.
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    South Korea followed the textbook principles of epidemiology. Kept deaths 40 times lower all the way till 75% of population fully vaccinated. This is success.
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    Just heard that it only costs $3 per dose for Pfizer and Moderna to make their COVID vaccine. But they sell it for $15-40 to the world. Given the amount of publicly funded research that went into development of these vaccines, & the current crisis, this is unacceptable.
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    India has more confirmed COVID cases per day than ๐—”๐—Ÿ๐—Ÿ other countries in the world ๐™˜๐™ค๐™ข๐™—๐™ž๐™ฃ๐™š๐™™.
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    A lot of COVID deaths in India in young people who should be doing well & recovering. I am making a plea to doctors in India to cut down the use of STEROIDS. Please. Steroids are only useful after the patient is hypoxic. Harmful if given early, or given for too long
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    Florida becomes first US state where the daily deaths in current wave have exceeded previous waves.
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    This is a plea to the US government to help India. What you can do: -Help with Oxygen & Oxygen generators -Release Astra Zeneca vaccine supplies -Lift the export ban & send them raw materials for vaccines As bad as this looks. It's 10 times worse. The Indian people need you.
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    Singapore should be a warning to us. They had COVID under excellent control. Now itโ€™s out of control: 728 new cases yesterday. When we relax social distancing measures prematurely we risk a second wave. Places where groups of people work/live close to each other are at high risk.
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    Omicron who? South Korea continues to be the role model. I hope they can sustain their science driven strategy which so far has saved hundreds of thousands of lives.
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    India has 1.3 billion people. 4 times that of the US. Whatโ€™s going on is just amazing and needs in depth immunologic studies. These are raw numbers!
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    There are at least 4 possible reasons why some people with COVID have little or no symptoms. 1) A rapid immune response that conquers the virus 2) Pre-existing cross reactive immunity 3) Genetic factors 4) Low viral load at time of infection We have emerging data for each. ๐Ÿ‘‡
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    One piece of positive news speaking to leaders of 2 large hospitals in India where most healthcare workers were fully vaccinated: No serious COVID cases among any of the vaccinated healthcare workers during this current crisis. The vaccines are working.
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    In randomized trials with 6 different COVID vaccines involving ~175000 persons: 0 hospitalizations for COVID in persons who received the recommended schedule of vaccine. That is ZERO.
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    The only people who have been consistently right on Covid have been those who have consistently raised the alarm.