Sebastian Caliri (@SebastianCaliri) / X

Sebastian Caliri

1,592 posts

Sebastian Caliri

@SebastianCaliri

Partner @8vc, former @palantirtech @stanfordmed

San Francisco, CA

goodreads.com/user/show/6387…

Joined October 2013

Pinned
Sebastian Caliri
@SebastianCaliri
Dec 3, 2025
Everyone knows about serious problems in American healthcare: $1.8T in federal spending, burned-out doctors, endless phone trees, incomprehensible bills. No-one has a viable plan to fix this mess. And rather than helping, our policies have effectively banned AI from medicine. We
251K
Sebastian Caliri
@SebastianCaliri
Oct 15, 2025
"Dad read the Silmarillion and bought a lot of domain names"
Sebastian Caliri
@SebastianCaliri
Oct 15, 2025
Move quickly, there aren't that many good LOTR names left to use.
270K
Sebastian Caliri
@SebastianCaliri
Oct 31, 2025
Some people want to ban billionaires. I love billionaires. They’re the last irrational actors left in capitalism. People don’t appreciate how difficult it would be to fund projects in longevity, space, fusion, etc without family offices and HNWs that can take crazy risks and
934K
Sebastian Caliri
@SebastianCaliri
Aug 18, 2025
Replying to @growing_daniel
Pelosi loaded up on Eucharist futures months ago
60K
Sebastian Caliri
@SebastianCaliri
Apr 18, 2025
Replying to @paulg
And there’s only one place in tech you can work if you want to make an impact on human trafficking , nuclear non-proliferation, protecting the American warfighter, accelerating the discovery of life-saving drugs, or keeping the NHS capable of caring for patients.
89K
Sebastian Caliri
@SebastianCaliri
Dec 9, 2024
Yale students have turned on her values. I guess I can just donate my PLTR stock to @uaustinorg instead.
Thomas Birmingham
@thomasbirm
Dec 8, 2024
BREAKING: Yale student body has voted OVERWHELMINGLY in favor of divesting the university’s holdings in weapons manufactures, including “those arming Israel” Of 3,338 students, over 76% voted in favor of divestment. @yaledailynews reports unprecedented engagement in the vote.
129K
Sebastian Caliri
@SebastianCaliri
Oct 15, 2025
Move quickly, there aren't that many good LOTR names left to use.
TBPN
@tbpn
Oct 15, 2025
BREAKING: US approves Erebor, a new bank from @PalmerLuckey and @JTLonsdale This is the fastest conditional approval for a depository institution de novo application in 25 years.
342K
Sebastian Caliri
@SebastianCaliri
Jan 22, 2024
Typical morning in SF: Vandals smashed a dozen planters in front of a restaurant that hasn’t even opened yet on the Embarcadero. I look forward to patronizing Alora as soon as it opens!
191K
Sebastian Caliri
@SebastianCaliri
Jan 28, 2025
The United States spends nearly 1/3 of the federal budget on healthcare. It is by far our biggest national expense, 2x defense and 100x what goes to border security. $800B buys us a world-beating military. But $1.5T on healthcare buys us a country that is overweight, dying
191K
Sebastian Caliri
@SebastianCaliri
Nov 15, 2024
“Bill Ackman is right” spotted at Yale. Vibe shift confirmed.
27K
Sebastian Caliri
@SebastianCaliri
Aug 15, 2025
The time has come to part ways with our long time blasting operator, Pardeep. Let me know if anyone is looking for a great blasting operator.
74K
Sebastian Caliri
@SebastianCaliri
Mar 6, 2024
Replying to @garrytan
MATH WINS BRUTAL VICTORY
76K
Sebastian Caliri
@SebastianCaliri
Apr 18, 2025
Replying to @paulg
Achieving concrete outcomes is different from working on a problem.
16K
Sebastian Caliri
@SebastianCaliri
May 15, 2025
Wow - some very positive news. Drug overdose deaths in the US are down 30,000 from their peak annual rate, between 2021 and 2024. This is incredible. A lot of room to go, but this is incredible.
Sebastian Caliri
@SebastianCaliri
Jul 16, 2021
Over 100,000 Americans will die from drug overdose this year, largely from synthetic opioids originating in Chinese state-owned enterprises. Just because media stopped reporting doesn't mean the problem is gone, & doesn't make the CCP any less culpable. cdc.gov/nchs/nvss/vsrr…
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