According to a new Science #Immunology study in mice, the #CD5 receptor limits CAR T cell activation and may contribute to poor outcomes from adoptive #Tcell #immunotherapies.
📄: scim.ag/7Jk
Science Immunology
3,511 posts
Science Immunology
@SciImmunology
Science Immunology publishes original, peer-reviewed research articles that report critical advances in all areas of immunological research.
- A new study from @VirusesImmunity, @YaleMed, @kaistpr, and @IcahnMountSinai finds that nasal #immunization is superior to injected immunization at producing mucosal lung IgA antibodies, protecting mice from #influenza. fcld.ly/c8uxzab
- “The prospect of achieving [containment of #SARSCoV2] with nasal vaccines is high, but will only be possible with dedicated funding, priority, and breaking down of any regulatory hurdles,” write @EricTopol and @VirusesImmunity in a new Editorial. fcld.ly/95ngl92
- In a recent Science #Immunology Review, researchers discuss ways in which genetic abnormalities enable #cancer cells to evade #antitumor immunity and resist treatment. scim.ag/4c7cJuz #DayOfImmunology
- This year's #NobelPrize in Medicine celebrates the discovery of regulatory T (Treg) cells. To celebrate, the Science #Immunology editors have highlighted recently published studies that advance understanding of #Treg cell biology. (THREAD 🧵)
- A recent Science #Immunology Review highlights the role of #DendriticCells in shaping TCell antitumor responses and explores how this interplay could be harnessed for cancer #vaccines. scim.ag/42pA7Am #DayOfImmunology
- Dendritic cells can “self-shape” the chemotactic gradients that help them transport antigens to lymph nodes, finds a new live imaging study from @Sixt_Lab @EdouardHannezo. 📄: scim.ag/3Wv Focus by @hannahdonnelly_ @EMandrou @robinsall: scim.ag/3Wu
00:00 - Studying ~56 million T cells from 55 COVID patients, researchers offer a high-res picture of epitope reactivity and TCR usage in CD8 T cells specific for #SARSCoV2, some of which also react to “common cold” coronaviruses. fcld.ly/u3psvf6 @RepertoireIM
- A 2022 Review by @EgleKvedaraite and @FGinhoux contextualizes over five decades of research on #DendriticCells and their roles in #cancer. Catch up on the work: scim.ag/6q8 #WeekendReads
- Human #DendriticCells need a unified nomenclature, write @EgleKvedaraite and @FGinhoux in a Review that summarizes 50 years of dendritic cell research and their functions in #cancer. 📎: fcld.ly/qqslaqh
- A new Science #Immunology Review discusses the mechanisms through which #DendriticCells influence cytotoxic CD8+ #TCell responses against cancer. @viditbhandarkar @stefanispranger scim.ag/4haL9hg
- The June issue of Science #Immunology is out! The cover spotlights two studies that examine how #RNA exosomes influence #Bcell development and dysfunction. More here➡️ fcld.ly/vsbi3es
- We'll be LIVE in less than an hour! In the meantime, check out this video from Sin-Hyeog Im, whose paper on the #probiotic Bifidobacterium bifidum appeared in the 19 October issue, and whose research will be discussed in out chat at 11 ET! Full vid here: facebook.com/ScienceImmunol…
00:00 - A new Science #Immunology Review examines the multifaceted ways in which T follicular helper cells modulate immune responses during infection, #allergy, and #autoimmune diseases. scim.ag/3SQqyoq
