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Schuh Lab
@SchuhLab
Illuminating the beginning of life at the Department of Meiosis, @mpi_nat. Account managed by Melina and Vanessa @SchuhLab.
Göttingen, Germany
mpinat.mpg.de/mschuh
Joined May 2018
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    Schuh Lab
    @SchuhLab
    Sep 17, 2025
    Honored to receive the Falling Walls Science Breakthrough of the Year 2025 (Life Sciences)! 🧬 With Tabea Lilian Marx, Christopher Thomas & our team, we filmed ovulation in real time — a dream come true. 👉 mpinat.mpg.de/5118437/pr_2518 #FallingWalls #ScienceSummit25
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    Schuh Lab
    @SchuhLab
    Oct 16, 2024
    Each month an #egg is ovulated from the #ovary, starting the journey of reproduction. But how does ovulation occur?🥚 Our latest work in @NatureCellBio led by @LastChrisThomas and @Tabea_Marx, describes the control of #ovulation using live imaging. bit.ly/3Ya8dEL (1/7)
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    Schuh Lab
    @SchuhLab
    Jun 20, 2024
    Women are born with all their oocytes, which need to stay viable for decades to ensure fertility. How are they maintained for that long? Our latest research in @NatureCellBio reveals that oocyte maintenance involves exceptional protein longevity. nature.com/articles/s4155… (1/9)
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    Schuh Lab
    @SchuhLab
    Oct 21, 2024
    Women lose >90% of their #eggs by their mid-30s, with persistent #DNADamage driving this loss. But why isn’t this damage repaired? Our new work in @CurrentBiology, led by @ninadini_sharma, reveals the causes of high DNA damage in aged oocytes.🧬💥 bit.ly/48e35Ee (1/13)
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    Schuh Lab
    @SchuhLab
    Feb 5, 2021
    A sperm fuses with an egg to form a zygote. After fertilization, the maternal and paternal chromosomes need to migrate and meet in middle of the zygote. Our latest work in @NatureComms reveals how this is achieved in mouse zygotes. (1/5) 🔗tinyurl.com/wghs1 @mpi_bpc
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    Schuh Lab
    @SchuhLab
    Nov 12, 2020
    We had so much fun taking our new group photo – fully Corona-safe! 😉📦 Special thanks to our fantastic media service @mpi_bpc for making this possible!🤗
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    Schuh Lab
    @SchuhLab
    Oct 21, 2022
    Oocytes rely on maternal mRNAs for development into healthy eggs. But where and how are these mRNAs stored? Our latest work in @ScienceMagazine shows that mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment (MARDO). bit.ly/3MNQSf1 (1/9)
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    Schuh Lab
    @SchuhLab
    May 7, 2021
    Only 1 in 3 fertilizations leads to a successful pregnancy. Embryo fate is often already decided directly after fertilization, when the chromosomes from each parent combine, as we report in our latest study (out now in @CellCellPress). cell.com/cell/fulltext/… (1/8)
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    Schuh Lab
    @SchuhLab
    Nov 2, 2023
    Our new paper in @CellCellPress answers a decades-old question: what is the function and composition of enigmatic structures called cytoplasmic lattices in mammalian oocytes? -> They are storage sites for essential proteins for the early embryo! bit.ly/45XwShG🧵(1/10)
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    Schuh Lab
    @SchuhLab
    Aug 27, 2020
    Did you know that 50-70% of human & bovine embryos have an incorrect number of chromosomes? The majority of errors arise in the early embryo, but where they come from was unclear. Our latest work on @biorxivpreprint sheds light on this important question. tinyurl.com/y52ze2mh
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    Schuh Lab
    @SchuhLab
    Feb 10, 2022
    Human oocytes separate chromosomes with an unstable spindle. This often causes aneuploidy, causing miscarriages & infertility. Our latest work in @ScienceMagazine shows why human spindles are so unstable, and how we can make them work more reliably. bit.ly/366wvZ9 (1/8)
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    Schuh Lab
    @SchuhLab
    Nov 23, 2023
    In the latest issue of @CellCellPress we show that mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Imagine the cytoplasm as a pantry with proteins stored on shelves made by cytoplasmic lattices! Thanks to @munafomarzia for the beautiful #SciArt!
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    Cell
    @CellCellPress
    Nov 23, 2023
    In the latest issue! Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices dlvr.it/SzD6pC
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    Schuh Lab
    @SchuhLab
    Aug 28, 2018
    Wondering whether you should become a PI? In this turning point piece in @NatureCellBio I share how it was for me to start my own lab (and a family in parallel). rdcu.be/5mv6
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    Schuh Lab
    @SchuhLab
    Jul 3, 2024
    Why do eggs in ovaries last for decades? Long-lived proteins may be key! Read more about our recent @NatureCellBio study and a related @eLife study by @NUDuncanLab in this nice news article in @ScienceMagazine.
    Why do eggs in ovaries last for decades? Long-lived proteins may be key
    From science.org
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