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Reiter Lab
@ReiterLab
How are #cilia built, how do they signal, how do they go awry to cause ciliopathies, and how do we fix them?
San Francisco, CA
Joined April 2011
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    Please read and critique our new paper on the genetic determinants of human kidney function @NatureGenet: rdcu.be/dTwye We combined GWAS with CNN and CRISPRi to go from loci to target genes. This roadmap may be useful to others uncovering genes underlying human traits.
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    Please read, send feedback and retweet link to free full-text work on how a variant cell cycle coordinates differentiation of multi ciliated cells: rdcu.be/dJmnv
    Multiciliated cell
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    Ever wonder how your gut grows to be more than 15 feet long? Well, wonder no more. Answers are here: rdcu.be/cCYQ6 The inimitable Ying Yang and colleagues provide some understanding of gut elongation. Turns out that growth requires ciliary signaling! 1/n
    GIF
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    Some end-of-the-year science! Chang Xie and colleagues have some super-interesting findings about how centrioles function in mammalian development: authors.elsevier.com/sd/article/S15… 1/n
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    Come join us here at UCSF! Ladder Rank Faculty Position - Assistant, Associate or Full Professor. It’s a great, supportive, wonderfully creative community except for the fact that you’re not already part of it: aprecruit.ucsf.edu/JPF04089
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    Okay, peeps, let me try my hand at this twitter thread thing, focusing on my personal highlights from @Melissa_Truong’s recent paper: authors.elsevier.com/a/1c%7Ez5L7PXe…
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    Up early to get to Bethesda to participate in an #NIH study section. This has got to be one of the most important things we do, right?
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    Heya #cilia and #Hedgehog tweeps! Shaun Abrams' paper is out @eLife in its evolutionary form. A 🧵 1/n:
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    Ahh. The look of discovery!
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    Please read about and comment on this alternative cell cycle that regulates differentiation of airway multiciliated cells: tinyurl.com/4a6yeuke. With a nice, concise explanatory thread from @semilc!
    We thought there wasn't much new to learn about the cell cycle. Turns out we were wrong! Our paper (out today @Nature) identifies a novel alternative cell cycle that regulates differentiation, not cell division. tinyurl.com/4a6yeuke. 1/10
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    New cilia signaling review written with @Hilgendorf_Lab and @Myers_lab and expertly edited by @lisa_heinke! Please read and give feedback. We tried to highlight existing barriers to progress, experimental innovations that might overcome them, and exciting future directions.
    Now Online Emerging mechanistic understanding of cilia function in cellular signalling dlvr.it/T2r8vD
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    We've had a great #FASEBCilia2024. Deep thanks to ⁦@PeterKJackson⁩ ⁦and @Mill_lab⁩ for co-organizing. My only regret is that we will have to end this fun and illuminating get-together! Until we re-gather, please stay in touch...
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    Welcome to the DISCO! @dhivkmr and our other wonderful colleagues show that a human ciliopathy-associated distal centriole complex (DISCO) is required to build distal appendages and, consequently, ciliogenesis.
    Dhivya Kumar @dhivkmr, @ReiterLab and colleagues identify a multi-protein complex called DISCO (DIStal centriole COmplex) that is essential for the initiation of cilium assembly. bit.ly/3dYZ3Vs #cilia #centriole #centrosome #cellbiology #biochemistry #cytoskeleton
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    We here at the Reiter lab are not shooting for our figures to be "almost painfully beautiful" but we'll take the compliment! Thank you, @ProfBootyPhD! (Lungs are beautiful, and I'm especially proud of Chang getting tricky pERK and p53 staining to work so well.)
    Lovely paper from the @ReiterLab - would be great to include in a developmental biology course. Almost painfully beautiful figures. cell.com/developmental-…