Roni Shouval (@RShouval) / X

Roni Shouval

913 posts

Roni Shouval

@RShouval

Precision Cellular Therapy | Attending - BMT and Cellular Therapy Service @sloan_kettering

Manhattan, NY

mskcc.org/research-areas…

Joined December 2018

Pinned
Roni Shouval
@RShouval
Apr 1, 2025
🚨 Just out @NatureMedicine! Introducing InflaMix—a point-of-care tool that identifies an #inflammatory 🔥 signature predictive of #CART failure in #lymphoma Led by Sandeep Raj (@SSRaj017) 👏@MSKCancerCenter nature.com/articles/s4159… 🧵Let’s break it down
An inflammatory biomarker signature of response to CAR-T cell therapy in non-Hodgkin lymphoma
From nature.com
14K
Roni Shouval
@RShouval
Dec 5, 2023
🎉 Exciting news! I'm thrilled to announce that I'm opening a lab at @MSKCancerCenter, dedicated to precision cellular therapy. We'll focus on novel computational methods to understand cellular therapy's effectiveness & toxicity. #CART #BMT #AI #multiomics
32K
Roni Shouval
@RShouval
Mar 13, 2022
Happy to share a new tool for transplant-related mortality risk stratification in allo-HCT - the Simplified Comorbidity Index (SCI). @DrMiguelPerales @joshuaafein @BloodAdvances #bmtsm @MSKCancerCenter @SHEBA_ doi.org/10.1182/blooda…
Roni Shouval
@RShouval
Jun 19, 2022
Guidelines for CAR-T Leukapheresis #cartcells sciencedirect.com/science/articl…
Roni Shouval
@RShouval
Dec 4, 2021
We wondered, what tumor-intrinsic features lead to #CARTcells resistance in large B-cell lymphoma? We‘ve seen that many of the ‘usual suspects’ (COO, DHL) don’t affect outcome in trials. GREAT collaboration @sloan_kettering @SHEBA_ @WeizmannScience 1/x
ascopubs.org
Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen...
PURPOSETumor-intrinsic features may render large B-cell lymphoma (LBCL) insensitive to CD19-directed chimeric antigen receptor T cells (CAR-T). We hypothesized that TP53 genomic alterations are...
Roni Shouval
@RShouval
May 7, 2023
Truly honored to receive the Clinical Investigator Career Development Award from the Lymphoma Research Foundation 🙏 @lymphoma #cure_lymphoma #CARTCells #resistance
13K
Roni Shouval
@RShouval
Oct 6, 2023
Wow! Genetic guidance of treatment in newly diagnosed #DLBCL sciencedirect.com/science/articl…
7.9K
Roni Shouval
@RShouval
Nov 4, 2021
#TP53 genomic alterations are detrimental in Large B-cell Lymphoma treated with #CART. Looking forward to sharing our data at #ASH21 ash.confex.com/ash/2021/webpr…
Roni Shouval
@RShouval
Jan 19, 2022
We investigated the source of bloodstream infections after fecal #microbiota transplantation (#FMT) in patients with steroid-resistant acute #GVHD doi.org/10.1182/blooda… @BloodAdvances @KorenLab @nagler_EBMT #microbiome #bmtsm 1/2
Roni Shouval
@RShouval
Sep 1, 2019
Excited to report @TheEBMT @joshuafein @Mohty_EBMT @nagler_EBMT outcomes by donor type in 100K allo-HCT pts. OS improving, with Haplo and Cord Blood driving the field in contemporary era. Yet, traditional donor hierarchy maintained MSD>MUD> alternative thelancet.com/journals/lanha…
Roni Shouval
@RShouval
Jan 31, 2021
Fantastic review on recent advances in CAR T. Mechanisms of resistance are better characterized for ALL. More work to be done in DLBCL #TcellRx nature.com/articles/s4156…
Roni Shouval
@RShouval
Oct 25, 2021
Excited to share our publication on adverse CV and pulmonary events associated with CAR-T therapy jacc.org/doi/full/10.10… @Adam_goldman_ @maor_elad @jennifer @JLiu_MSKCardOnc @mayocvonc @joshuaafein @saadhealth @DrMiguelPerales @JACCJournals #TcellRx 1/x
Adverse Cardiovascular and Pulmonary Events Associated With Chimeric Antigen Receptor T-Cell...
From jacc.org
Roni Shouval
@RShouval
Feb 2, 2022
Resistance to #CARTcell therapy independent of target antigen loss - an evolving paradigm. Another useful review from Jean Lemoine, @MarcoRuella @HouotRoch. rdcu.be/cGcWV
Roni Shouval
@RShouval
Feb 25, 2021
Proud to share our work @joshuaafein "Development and validation of a disease risk stratification system (DRSS) for patients with haematological malignancies: a retrospective cohort study of the EBMT registry" thelancet.com/journals/lanha… 1/11