#ScienceSaturday
❓ Why do T cells sometimes fail to fight cancer?
➡️ A new study in Nature shows that when T cells are exposed to cancer or long-term infections, they can enter a state called exhaustion, where they lose their ability to eliminate harmful cells.
➡️ The
Dr. Patrick Hwu
6,003 posts
Moffitt Cancer Center President and CEO, @MoffittNews. Tumor immunologist. Inspired leader. Girl dad. #DocsWhoRock. Driven to save more lives from #cancer.
- Meet the first patient in the world to receive Tecelra, a groundbreaking engineered cell therapy for synovial #sarcoma. This is a powerful story of resilience and innovation—and I’m so proud of our team @MoffittNews for leading the way in this area!
- Happy Anniversary Katie! I couldn’t have a more loving and supportive partner. 31 incredible years and the best is yet to come!
- #ScienceSaturday ❓ Why do some cancers resist immunotherapy? ➡️ A recent study in Nature found that certain cancers can “trick” the body’s immune system. They do this by changing how cells in the bone marrow develop. These changes cause more immune cells called macrophages to
- The Hwu Lab mourns the loss of one of our own, Dr. Deb Silverman @deb_silverman, who was so courageous in the face of breast cancer at such a young age. I’m so happy Deb was able to receive her Ph.D. and that she could visit from @MDAndersonNews to join our last lab team outing.
- About 1/3 of all cancers diagnosed annually can be prevented, and more can be cured by early detection through screening. Do you know what #cancer screenings you should get? Check out the recommended screenings and prioritize your health this New Year!
- (1/2) Immune response against #cancer can be inhibited by myeloid derived suppressor cells (MDSCs). Defining and studying MDSCs has been challenging due to the lack of specific surface markers. science.org/doi/10.1126/sc…
- So sad to hear about the passing of Jeff Weber, a giant in the field of oncology. He was involved in the early days of cytokine and cell therapy and most recently led studies of personalized vaccines for melanoma patients. I originally worked with Jeff @theNCI over 30 years ago.
- I've officially surpassed my first 100 days @MoffittNews and thought it was time to get connected to the world in a new way on Twitter. I'm looking forward to inspiration, collaboration and conversation. More on why I've joined moffitt.org/endeavor/archi…
- It’s only appropriate that every few years our anniversary lands on #Thanksgiving. Grateful for 32 incredible years together and the best is yet to come! Happy Anniversary to my wife, Katie!
- It was an honor to attend The @WhiteHouse Holiday Reception last night. We appreciate the commitment and support of @POTUS and @FLOTUS for cancer prevention, screening and research and to eliminate disparities in #cancer outcomes.
- #ScienceSaturday For #immunotherapy to be effective, T cells need to effectively infiltrate tumors. In this preclinical study, low molecular weight heparin was found to enhance T cell infiltration and anti-tumor efficacy for both adoptive T cell therapy and immune checkpoint
- What makes cancers regrow after therapy? Many cancers initially respond well to treatment but then progress due to resistant “persister cells”. nature.com/articles/d4158…















