I have zero respect for a researcher, perched in an ivory tower publishing thousands of papers, who publicly tells a practicing clinician, who spends their day caring for patients, that they are a "nobody" because they have not published a paper.
Michael Mindrum, MD
23.8K posts
Michael Mindrum, MD
@MichaelMindrum
Internal Medicine & obesity specialist. Born in 🇺🇸, 🇨🇦 is home.
- People don’t like obesity drugs because there is a belief that obesity is a moral sin and that they should suffer, repent, and go through hardship to find redemption.
- 🔥 Obesity is not a behavior. Let that sink in. It’s not about eating too much, exercising too little, or lacking willpower. It’s a chronic, complex condition driven by biology, environment, and genetics—not simple “choices.” Let me explain. 1/10
- How is it legal to advertise you are an oncologist when you are not one? How can you treat patients with cancer with medications and not have a medical license? And how does this generate 500 k followers?
- 1/ Ghrelin, the "Hunger Hormone". Hunger isn’t just a feeling—it’s a finely tuned biological response. Ghrelin connects the gut, brain, energy use, storage, and tissue repair. Let me explain: 🍽️ 🧵
- Leptin is more than a satiety hormone—it's a central player in energy balance, behaviour, and our non-conscious response to palatable foods. Lets' take a look 👀. A 🧵 1/12
- Replying to @MichaelMindrum🙅♂️ Saying “eat less, move more” is like telling someone with asthma to “breathe better.” It oversimplifies, stigmatizes, and blames people for a condition largely out of their control. Science demands better. #HealthStigma
- 1/ Over a century ago, scientists uncovered a curious link between the gut & the pancreas. This sparked decades of research, culminating in one of the greatest medical breakthroughs. This is the story of GLP-1 that I would like to share. 🧵
- We increasingly understand obesity as a brain-based disease. This review by Zagmutt et al., 2025 maps how subtle inflammation in the hypothalamus evolves over time offering a clearer picture of when and how metabolic regulation begins to fail. 1/5
- Replying to @MichaelMindrum💡 Obesity is not a behavior. It’s time we stop pretending it is and start treating it with the evidence, compassion, and care it deserves. Science wins over blame every time. #TakeThatToTheBankMAHA
- A personal story of irrational nutrition bias. Several years ago I started a ketogenic diet to better understand it for my patients. I remember sitting down for my first steak (not that keto has to include steak) & fought this deep feeling that a heart attack was now imminent.
- Replying to @MichaelMindrum🎯 The takeaway: Treating obesity like a behavior misses the point entirely. It’s a chronic condition requiring medical, behavioral, and environmental solutions. Real progress starts when we separate the disease from the stigma. #ObesityScience
- Replying to @MichaelMindrum🔬 Obesity is a disease of energy regulation. Hormones like leptin, ghrelin, and insulin interact with your brain to control hunger, fullness, and fat storage. In obesity, these systems are disrupted, often by genetics and environment. #ObesityResearch 3/10
- Replying to @MichaelMindrum💡 People think obesity is a behavior because it looks like one. “They just eat too much.” But that’s like saying fever is a behavior because they have feel hot. Obesity is the symptom of underlying dysregulation. #ObesityScience 2/10