Keeping a beady eye on the data. Time to apply the Feuerstein-Ratain rule to a clinical readout from #ASCO26 – a specific use case with a stark reminder:
tinyurl.com/mr2fbua2
Given the interest at #ASH23 in a German study on CD19 CAR-T cells in autoimmune diseases such as systemic lupus erythematosus (SLE), a potentially life threatening condition – what can we learn from prior data? A short thread 🧵...
There are no words to describe the sadness and utter desolation one feels when a dear friend of 30 years suddenly passes. Gone far too young, may he rest in peace. I shall miss his exuberant spirit greatly.
I'm delighted to say we hit our 5-year anniversary this week for BSB as a specialist oncology paid subscription service... many thought we'd last 6 mon - here we still are, going from strength to strength! Thanks to all our supporters and fans.
Nice review from Jim Allison and colleagues on "Fundamental mechanisms of immune checkpoint blockade therapy" - explaining diffs in targeting PD-1 and CTLA4: cancerdiscovery.aacrjournals.org/content/early/…
There is a huge need to develop immunotherapies to enhance T cell responses against "immunologically 'cold' tumours" with low T cell infiltration and neoantigen burden. Despite numerous company efforts, there have been few successes to report...
Whoa 3 hours post vaccine waiting for the next #aacr21 session and light headed with tingling hands, headache and chills. My T cells are busy doing their job! 🙏
This has to be one of the most idiotic, rude, and ill advised tweets I’ve seen in 2020 given the sheer cultural diversity & productivity of cancer research labs in my stream every damn day...