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Mark Pimentel MD
@MarkPimentelMD
Executive Director, @MASTprogram. A program finding solutions to diseases of the human #microbiome such as #SIBO, #IBS, #Metabolicdisorders @CedarsSinai
Los Angeles
csmast.com
Joined May 2014
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  • Pinned
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    Mark Pimentel MD
    @MarkPimentelMD
    Apr 23
    NEW STUDY: I don't ask for things often but we are recruiting a trial for new therapy for irritable bowel syndrome with diarrhea (#IBS -D) based on #microbiome. Please retweet to spread the word to patients in the LA area. Here is the link to contact us iredcap.csmc.edu/surveys/?s=TD7…
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    Mark Pimentel MD
    @MarkPimentelMD
    Apr 20, 2020
    Pivot. Our team has spent the last 6 weeks, 16 hours a day, 7 days a week working on #COVID. We have developed a device to kill coronavirus with @MASTprogram @CedarsSinai hoping to bring to humans in weeks with help of @SterlingMedDev and @BioscienceAytu. finance.yahoo.com/news/aytu-bios…
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    Mark Pimentel MD
    @MarkPimentelMD
    Sep 19, 2022
    Our study is out! #IBS has three main microtypes. H2S gas (Desulfovibrio & Fusobacteria) drives diarrhea, H2 producers (E. coli & Klebsiella) driving SIBO type, and Methanobrevibacter (CH4) driving constipation. Forms the basis for new treatments coming. journals.lww.com/ajg/Abstract/9…
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    Mark Pimentel MD
    @MarkPimentelMD
    Apr 22, 2020
    The mantra is "when you see something...then think of something...and do something...". We completely shifted gears to #COVID and introduce #healight. Thanks @AliRezaieMD @gym99 @RuchiMathurMD @GabrielaGSLeite Chus, Gonzalo, and entire @MASTprogram. More updates tomorrow.
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    Mark Pimentel MD
    @MarkPimentelMD
    Aug 2, 2018
    Unbelievable! Just heard yesterday that in a board review course video (for GI certification) on #IBS, the doctor stated that #IBS is a "disease of anxious and nervous women". WHAT!? Where was this person for the last 15 years. NO! It's not.
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    Mark Pimentel MD
    @MarkPimentelMD
    Feb 11, 2025
    Great news from #DDW2025. This will be a huge year. Big results on three new therapies for #SIBO/#IBS, #IMO (intestinal methanogen overgrowth) and #ISO (intestinal sulfide overproduction). Patients have been waiting a long time for drug therapies.
    19K
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    Mark Pimentel MD
    @MarkPimentelMD
    Feb 3, 2022
    Happy to announce, covering years of work, our new book with @AliRezaieMD on the #microbiome and #IBS/#SIBO. Covering many new concepts that we hope will help people and their doctors better understand this condition. On Amazon and coming out April 12!
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    Mark Pimentel MD
    @MarkPimentelMD
    Apr 7, 2021
    #diarrhea but not just any diarrhea...unpredictable diarrhea. #Bloating and uncomfortable distension with most foods. Being told to "live with it". This is what #IBS patients experience. "Live with it" is NOT acceptable in 2021! #IBSAwarenessMonth
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    Mark Pimentel MD
    @MarkPimentelMD
    May 17, 2024
    If you define a disease by symptoms, all you get are treatments for symptoms. If you define a disease by cause, you get cures. Here's to pathophysiology of GI diseases at #DDW2024 starting tomorrow.
    12K
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    Mark Pimentel MD
    @MarkPimentelMD
    Sep 30, 2019
    We are retooling our 5 year plan for #IBS and #SIBO based on data from the #REIMAGINEstudy. Now we know who the culprit bugs are. Already have plans for at least two new treatments that should work better. Will post more soon.
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    Mark Pimentel MD
    @MarkPimentelMD
    Apr 29, 2025
    I apologize in advance but I will be posting A LOT in the next 7 days from @DDWMeeting. There are so many great things and new treatment data. Simultaneously, we have some important papers coming out. Stay tuned #SIBO #IBS #GERD and others.
    12K
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    Mark Pimentel MD
    @MarkPimentelMD
    Feb 24, 2024
    Fun fact. There are about 528 million #twitter users. That means there are 52 million people with #IBS/#SIBO on Twitter suffering with unpredictable abdominal pain, bloating and diarrhea/constipation. New treatments are coming!
    12K
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    Mark Pimentel MD
    @MarkPimentelMD
    May 30, 2019
    I heard a recent speakers say "IBS is not a disease"... There is a proven derangement of the small bowel #microbiome in #IBS, There is a blood test that can diagnose #IBS. Food poisoning causes a large proportion of #IBS. FDA approved drugs can remedy. #IBS is a disease!
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    Mark Pimentel MD
    @MarkPimentelMD
    Aug 2, 2024
    If we continue to base #IBS diagnosis on symptoms, we will continue to get drugs that just treat symptoms (and have no grants to fund research). Time to base diagnosis and treatment on pathophysiology in the gut.
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