#Neoadjuvant chemoradiotherapy improved⬆️ 5-yr OS in pts with resectable & borderline resectable #PancreaticCancer in the long term results multicenter #PREOPANC-1 RCT (2013–2017) in 246🇳🇱pts: 20.5% vs 6.5% after upfront surgery ascopubs.org/doi/10.1200/JC… #alvleesklierkanker
Marc Besselink
3,323 posts
Professor of pancreatic and hepatobiliary (HPB) surgery, Amsterdam UMC - Dutch Pancreatic Cancer Group, Dutch Pancreatitis Study Group. IHPBA 2030-Netherlands
- Today @NEJM: POINTER trial @pancreatitis_nl: immediate drainage of infected necrotizing pancreatitis does not improve outcome. In fact, postponed drainage approach: 39% only required antibiotic tx and 22% necrosectomy. Wonderful 🇳🇱 nationwide collab! nejm.org/doi/full/10.10…
- The 3 Presidents-elect #IHPBA22 @Shrikhande_SV for #APHBA, Majella Doyle for @AHPBA, and @MarcBesselink for @EAHPBA: building our collaboration within @IHPBA to improve outcome for patients with HPB disease!
- “#COVID19 may present itself as abdominal, @pancreatitis like, pain only!” Presented today @Netherlands 🇳🇱 online webinar Dutch specialists who treated these pts themselves. Be aware @AnnalsofSurgery and keep surgeons, residents safe. Glasses, masks, gloves! #COVID19surgery
- Today @ASCO: Survival benefit w/ neoadj chemoradiotherapy vs upfront surgery&adj gem: LTFU #PREOPANC RCT in 246 pts w/ resectable and borderline res #Pancreatic #Cancer 16 🇳🇱 centers @DPCG_official; 5yr OS 20% vs 6%. Limitation: trial from the pre-FFX era. ascopubs.org/doi/abs/10.120…
- “So, a soft pancreas ➡️ main driver of fistula ➡️ majority of deaths in #Whipple #surgery”📛 💡 “What if we use #SBRT to induce fibrosis preop in non-PDAC (!) pts. Would it work? Could we prevent POPF?”✅ Did anybody try this before?? ☢️ Happening now in the #FIBROPANC pilot
- Thank you @EHPBA for your trust in me as #President ‘23-‘25 #EAHPBA2023 The future is 🌟 with this #DreamTeam of new commitee (vice) chairs incl new secretary-general @iisifrigerio and @AAFretland @Gio_Marchegiani @berrevoet @JorgKleeff @Abuhilal9Abu @TomGallagherHPB @ksoreideProfessor @MarcBesselink taking the mantle of @eahpba President from Professor Siriwardena 👀⏩ 1. 1st International HPB Mentorship programme 2. Webinar programme of education 3. Early career group 4. Intensification of research Exciting times ahead! Great close to #EAHPBA23
- Is #ChatGPT useful in #Surgery #Science? ✅ Yes! See our leading article in @BjsOpen where @BorisJanssen shows you how #ChatGPT helped us to write the article and a grant application in #HPBsurgery 😀 doi.org/10.1093/bjsope…
- Today @TheLancet; #PORSCH RCT, nationwide algorithm-based care: mortality ⬇️ organ failure ⬇️ bleeding ⬇️ after #Pancreatic #Surgery 🇳🇱. Algorithm available via @DPCG_official app: apps.apple.com/nl/app/pancrea… 👍Hjalmar van Santvoort thelancet.com/journals/lance…
- Seminar #Acute #Pancreatitis today @TheLancet: summarizing the latest evidence on work-up, conservative tx and (timing of) interventions, prevention. Incl the newest RCTs by @pancreatitis_nl ao Free link: eur04.safelinks.protection.outlook.com/?url=https%3A%…
- Today @NatRevGastroHep: Diagnosis and management of #pancreas cystic neoplasms: current evidence and comparison of the European @my_ueg, International and @AmerGastroAssn #guidelines. Towards one-global-guideline! #PancreaticCancer #alvleesklierkanker
- CHOCOLATE multicenter RCT: lap cholecystectomy superior to perc catheter drainage in 142 high risk pts with acute calc #cholecystitis: #surgery reduced complications (12 vs 65%), reinterventions (12 vs 66%) and disease recurrence (5 vs 53%) bmj.com/content/363/bm… @IHPBA @my_ueg
- Very happy to announce “IHPBA2030 The Netherlands”🇳🇱!! Thank you @DPCG_official & @pancreatitis_nl and all working groups! Thank you @IHPBA & @EAHPBA for your trust! Thank you @RAI_Amsterdam @carlijnbuis @julia_menso @BasGrootKoerkam @laarhoven_stijn @Caspervaneijck
- Professor John Cameron, living legend 👑 and one of the first Trialists in #pancreatic #surgery: 88 years but alive and kickin’ at @AmerSurg in San Diego🇺🇸 A true leader by example and inspiration for all of us!! @IHPBA @EAHPBA @AHPBA @HopkinsMedicine








































