user avatar
Krishnaswamy Lab
@KrishnaswamyLab
We develop data deep learning methods containing geometric, topological, dynamic systems-based constructs for discovery from scientific and biomedical data.
Yale University
krishnaswamylab.org
Joined February 2017
1,227
Following
7,230
Followers
Posts
  • Pinned
    user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Feb 8, 2021
    Today, I’m proud to share our latest work published in @NatureBiotech describing MELD, a #MachineLearning algorithm for #SingleCell perturbation analysis. Read this #tweetorial to learn about the work led by @dbburkhardt and Jay Stanley 🥳🎉🧪 nature.com/articles/s4158… (1/16)
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Mar 10, 2021
    All materials from our Machine Learning for Single Cell Analysis workshop (January 2021) are available freely online now, including the lectures. Everything can be found at krishnaswamylab.org/workshop (including a link to the lectures on youtube youtube.com/playlist?list=…) !
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Jul 1, 2022
    Happy to share that the board of permanent officers both of @YaleMed and @Yale FAS have approved my tenure starting today. Honored to be one of the very few people tenured by both units. Glad to be a fully joint associate professor in @YaleCompsci and @YaleGenetics !!
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    May 16, 2022
    We made the cover!! Check out multiscale phate in this issue!!
    user avatar
    Nature Biotechnology
    @NatureBiotech
    May 16, 2022
    The May issue is live nature.com/nbt/volumes/40… On our cover, disease signatures in high-dimensional biomedical data are detected with a visualization algorithm go.nature.com/3K0QCqi
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Mar 7, 2022
    @AmodioMatt passed his defense!!
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Jun 25, 2020
    Comp bio folks: can we all start to put our method in the "Results" section? I am reviewing a paper whose contribution is a beautiful method ... that you have to excavate from supplementary information. My first Result section in every paper I wrote is the method. It works!
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Dec 3, 2019
    Excited that PHATE, our dimensionality reduction and #dataviz method, is out today in @NatureBiotech! Congrats Kevin Moon, @david_van_dijk, @scottgigante and @mrguywolf. #tweetorial coming soon!
    Content cover image
    Visualizing structure and transitions in high-dimensional biological data
    From nature.com
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Sep 26, 2022
    (1/10)Pleased to share that our work on leveraging deep transformer-based representation learning for protein sequence optimization is out today in @NatMachIntell ! nature.com/articles/s4225…
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Jul 20, 2021
    Honored to receive the NSF CAREER Award for our proposal: "Deep representation learning for exploration and inference in biomedical data." Thanks to the entire lab for the great work!
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Dec 3, 2019
    TWEETORIAL: PHATE, our dimensionality reduction and #dataviz method featured on the cover of today’s @NatureBiotech! To help spread the word, @scottgigante and @dbburkhardt put together this #tweetorial for you. nature.com/articles/s4158… (1/10)
    user avatar
    Nature Biotechnology
    @NatureBiotech
    Dec 3, 2019
    The December issue is live nature.com/nbt/volumes/37…
    Content cover image
    Visualizing structure and transitions in high-dimensional biological data
    From nature.com
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Apr 1, 2023
    (1/n) Today I'm proud to present our work on learning dynamics in cancer using neural ODEs and optimal transport!
    biorxiv.org
    Learning transcriptional and regulatory dynamics driving cancer cell plasticity using neural...
    While single-cell technologies have allowed scientists to characterize cell states that emerge during cancer progression through temporal sampling, connecting these samples over time and inferring...
    37K
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Sep 8, 2022
    Honored to receive this award and be listed alongside amazing scientists Arlene Sharpe and @SalliePermar !
    user avatar
    Yale Engineering
    @YaleEngineering
    Sep 8, 2022
    Congrats to Smita Krishnaswamy for winning the Excellence in Science Award Early-Career Investigator Award from the FASB! The award recognizes the research, teaching and community efforts she has made in the scientific community: seas.yale.edu/news-events/ne…
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Dec 20, 2024
    (1/n) Excited to share our work on gene signal pattern analysis (GSPA), an new way of analyzing gene expression over cellular manifolds! Out today!
    nature.com
    Mapping the gene space at single-cell resolution with gene signal pattern analysis
    Nature Computational Science - This work presents a graph signal processing method, gene signal pattern analysis, to embed gene signals from single-cell sequencing data. In diverse experimental...
    13K
  • user avatar
    Krishnaswamy Lab
    @KrishnaswamyLab
    Apr 25, 2023
    Some perspective for scientists who may be asked to review computational methods: Computational methods are indeed innovated by taking existing mathematical and algorithmic atoms and putting them together in a novel way. Second, small changes in the steps can have a large
    28K