Our latest! Single nucleus mouse brain atlas of >110,00 DNA methylomes- many cool observations incl spatial gradients! Kudos to our @salkinstitute @UCSD @NIMHgov Center for BRAIN Epigenomics & leads Hanqing Liu & Jingtian Zhou biorxiv.org/content/10.110…
Joe Ecker
639 posts
I'm a scientist
- Amazing work from collaborator Bing Ren lab! Probing accessible chromatin in >800,000 brain cells, and to define 491,818 candidate cis regulatory DNA elements in 160 distinct sub-types. biorxiv.org/content/10.110…
- Thanks to the amazing lead author @YupengHe, all lab members @salkinstitute & terrific @ENCODE_NIH collaborators BingRen @CEpigenomics @AxelVisel @LenPennacchio Woldlab @Caltech contributing to “Spatiotemporal DNA methylome dynamics…” in today’s @Nature nature.com/articles/s4158…
- Reading the epigenomes of 100k+ brain cells as part of #BICCN -remarkable work by students @Hanq_Liu, Jingtian Zhou and postdocs Zhuzhu Zhang, Wei Tien and all our amazing #BICCN collaborators nature.com/articles/s4158… nature.com/articles/s4158… nature.com/articles/s4158…
- We will miss you. Go do great things!Today is my last day as a postdoc at @salkinstitute. Over the past 5+ years, I've enjoyed incredible intellectual stimulation and fun. A huge thank you to @JoeEcker and all my colleagues and friends for making my time in San Diego so special!!!
- Amazing work from @Schmitz_Lab and Xiaou Zhang in @NaturePlants nature.com/articles/s4147… and nature.com/articles/s4147… "Identification of cis-regulatory elements, or CREs in 13 plant species, including maize, rice, green beans and barley" Essentially a plant kingdom ENCODE project!
- Our protocol “ Single-cell multi-omic profiling of chromatin conformation and DNA methylation “ has now been posted online: doi.org/10.21203/rs.2.….Single-nucleus methyl-3C sequencing (sn-m3C-seq) from @JoeEcker and @Jesse_R_Dixon from @salkinstitute looks at both 3D chromatin organization and DNA methylation in single cells. nature.com/articles/s4159…
- Congratulations to my colleague Joanne Chory.! After decades of pioneering research in understanding of plant growth, she continues to break new ground and inspire all of us to think out of the box.
- New preprint on Epi-Retro-Seq profiling of ~12,000 single neuron DNA methylomes from 63 cortical projections. Great work from @salkinstitute @UCSD @NIMHgov funded Center for BRAIN Epigenomics team & esp lead authors Zhuzhu Zhang & Jingtian Zhou @HHMINEWS biorxiv.org/content/10.110…
- Heartiest congratulations to my Salk colleague Joanne Chory and to Elliot Meyerowitz (Caltech)for being awarded the 2018 Gruber Genetics Prize for their pioneering studies in plant development and hormone biology! gruber.yale.edu/prize/2018-gru…
- Replying to @emukamelThis was a great collaboration using multi-omic snmCT-seq (DNA methylome+transcriptome) technology developed by @chongyuanluo and @JoeEcker , co-led by Marga Behrens, with @Hanq_Liu , @Bang1An and other superstars sciencedirect.com/science/articl…
- Congratulations to my amazing colleague on this well deserved honorOne minute about the 2024 Wolf Prize Laureate in Agriculture - Joanne Chory
00:00 - It’s a great pleasure to work with such an amazingly collaborative group of neuroscientists, computational and molecular biologists in the BRAIN Initiative Cell Census Network. This is just the first fruit of the BICCN effort. biorxiv.org/content/10.110…
















