JelenaBezbradicaLab (@JelenaLab) / X

JelenaBezbradicaLab

470 posts

JelenaBezbradicaLab

@JelenaLab

Oxford

kennedy.ox.ac.uk/research/innat…

Joined March 2020

Pinned
JelenaBezbradicaLab
@JelenaLab
Apr 17
How lytic cell death drives autoantigen release and fuels inflammation? With @lynndustinlab we ask this using a common autoantigen, TRIM21. The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death | Science Immunology
science.org
The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death
TRIM21/Ro52 assembles proinflammatory immune complexes.
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JelenaBezbradicaLab
@JelenaLab
Sep 15, 2021
TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation pnas.org/content/118/38… Very proud of our young lab and grateful to our friends for making this project happen.
pnas.org
TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation | PNAS
NACHT, LRR, and PYD domains–containing protein 3 (NLRP3) inflammasome activation is beneficial during infection and vaccination but, when uncontrol...
JelenaBezbradicaLab
@JelenaLab
Aug 24, 2021
Research assistant position available in our group. If you are interested in macrophage biology and inflammasomes please contact us and apply using link below. We are looking forward to meeting you! my.corehr.com/pls/uoxrecruit…
JelenaBezbradicaLab
@JelenaLab
Dec 15, 2023
Our review with @ClareBryant13 is out in @emboreports We discuss an emerging model of how inflammasomes may integrate pathogen- and tissue-injury signals, with changes in tissue mechanics, to shape the downstream inflammatory responses and allow cell and tissue mechano-adaptation
EMBO Reports
@emboreports
Dec 15, 2023
A new review is online! Jelena Bezbradica and Clare Bryant @ClareBryant13 @inflammedlab @Cambridge_Uni tell you all you need to know on #inflammasomes as regulators of #mechano-#immunity. -> embopress.org/doi/full/10.10…
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JelenaBezbradicaLab
@JelenaLab
Sep 15, 2021
Proud PI moment: two talk awards to two amazing students @FabiAlexFischer and Sara Danielli (it is time you get a twitter account Sara!) 😁
JelenaBezbradicaLab
@JelenaLab
Mar 22, 2022
And that is a smile of one amazing PhD graduate! Congratulations @_SaraDanielli_ Starting a lab with you has been such fun! Watch out for a great work from Sara, after we finish celebrations 🎉!
JelenaBezbradicaLab
@JelenaLab
Apr 2, 2021
Check out our new review on Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation frontiersin.org/article/10.338… What a fun it was to write this with Fabian Fisher and Kaiwen Chen @_kaiwenchen!
JelenaBezbradicaLab
@JelenaLab
Feb 1, 2024
Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting: Cell Reports, a cool study by @ClareBryant13 and colleagues.
Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflamma...
From cell.com
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JelenaBezbradicaLab
@JelenaLab
Jul 18, 2022
I am one very proud PI: @KirOxford student @FabiAlexFischer presenting his work at #EESImmunity. Zoom in if you want to see Fabi 🤣🔎well done, and claps from your lab 👏👏👏
JelenaBezbradicaLab
@JelenaLab
Sep 27, 2024
And that's a wrap of #EMBOInflammasomes2024! enjoyed it, with the best team @Ada_Liebenau @maadulon @Katie_H9 @gchappell9 and Su Qi 👌
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JelenaBezbradicaLab
@JelenaLab
Jul 20, 2022
Hi friends, here is a much better picture of @FabiAlexFischer, and his smile 🙂... This time with the poster award! Congratulations @FabiAlexFischer and thank you @embl 🙏
JelenaBezbradicaLab
@JelenaLab
Jul 18, 2022
I am one very proud PI: @KirOxford student @FabiAlexFischer presenting his work at #EESImmunity. Zoom in if you want to see Fabi 🤣🔎well done, and claps from your lab 👏👏👏
JelenaBezbradicaLab
@JelenaLab
Dec 5, 2022
Wow, future is looking bright! Students are giving amazing talks at Bright Sparks session of #bsi22 Here is one from our own @FabiAlexFischer
JelenaBezbradicaLab
@JelenaLab
Mar 2, 2023
So proud to share these results of our own @_SaraDanielli_ joined by the team of Kevin Foskett at UPenn. Together, we describe a role of TLR and IFN-induced protein called CALHM6, in licencing macrophage cross-talk with natural killer cells upon infection
The ion channel CALHM6 controls bacterial infection‐induced cellular cross‐talk at the immunologi...
From link.springer.com
6.3K
JelenaBezbradicaLab
@JelenaLab
Dec 8, 2023
Wooohoooo: Fabi is now Dr Fabi 👏🙂 @FabiAlexFischer one of the most deserving and enthusiastic students I have met. Huge congratulations Fabi, next steps are looking really great. Thank you to our supportive examiners @BenediktKessler @FelixRandow 🖐
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