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Jason Sheltzer
@JSheltzer
Assistant prof at @StanfordMed. Interested in aneuploidy, mitotic kinases, cancer therapeutics, and drug development. Co-founder x2.
sheltzerlab.org
Joined February 2016
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  • Pinned
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    Jason Sheltzer
    @JSheltzer
    Jul 6, 2023
    Check out our new study in @ScienceMagazine, where we take on a 100-year-old debate: what’s the role of aneuploidy in cancer? We discovered that genetically removing extra chromosomes blocks cancer growth - a phenomenon we call “aneuploidy addiction”.
    science.org
    Oncogene-like addiction to aneuploidy in human cancers
    Specific aneuploidies benefit cancer cells and may be sensitive to treatment
    385K
  • user avatar
    Jason Sheltzer
    @JSheltzer
    Jun 15, 2020
    An amazing *randomized trial* on Twitter+academia: 112 papers were randomly chosen to be shared on twitter by a group with ~58k followers or to not be shared. Papers that were tweeted accumulated 4x more citations compared to non-tweeted papers over 1yr. pubmed.ncbi.nlm.nih.gov/32504611/
  • user avatar
    Jason Sheltzer
    @JSheltzer
    Jun 29, 2018
    Great new study about science outreach via Twitter: Initially, scientists mostly tweet to each other. But after accumulating about 1000 followers, scientists reach an increasing number of journalists, policy makers, and other members of the public. facetsjournal.com/doi/10.1139/fa…
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    Jason Sheltzer
    @JSheltzer
    Oct 7, 2024
    Another scientist whose work initially didn't get the recognition that it deserved - Victor Ambros was denied tenure at Harvard, even after publishing the seminal work that resulted in him receiving the Nobel Prize today!
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    The Nobel Prize
    @NobelPrize
    Oct 7, 2024
    BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
    400K
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    Jason Sheltzer
    @JSheltzer
    May 9, 2023
    Fascinating new preprint on bioRxiv tackles a whale of a question: Whales are huge. So why don’t they get a ton of cancers? biorxiv.org/content/10.110…
    991K
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    Jason Sheltzer
    @JSheltzer
    Nov 13, 2017
    My mom has degrees in biology, chemistry, and medicine, and has more Pubmed papers than I do. Can we *please* drop this sexist standard from science communication?
  • user avatar
    Jason Sheltzer
    @JSheltzer
    Jul 15, 2019
    Let’s play a little game. Let’s say that you’re the CSO at a cancer pharma company, and you have to choose a target to go after. Here’s a gene – high expression is associated with poor prognosis in brain cancer. Looks like a good candidate for an inhibitor right?
  • user avatar
    Jason Sheltzer
    @JSheltzer
    Aug 28, 2022
    I want the US to be a mecca for the world’s scientific talent. If you’re a scientist fighting for a green card, and your research involves cancer, aneuploidy, kinase inhibitors, or anything else that I know a little about, please send me a USCIS letter and I’ll gladly sign it.
  • user avatar
    Jason Sheltzer
    @JSheltzer
    Jan 24, 2021
    In a blinded name-swap experiment, black female high school students were significantly less likely to be recommended for AP Calculus compared to other students with identical academic credentials. Important new paper from @DaniaFrancis: smith.edu/sites/default/…
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    Jason Sheltzer
    @JSheltzer
    Oct 9, 2024
    John Jumper went from getting a PhD to getting a Nobel Prize in just seven years!
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    The Nobel Prize
    @NobelPrize
    Oct 9, 2024
    BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
    704K
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    Jason Sheltzer
    @JSheltzer
    Oct 3, 2022
    Pääbo's father, Sune Bergström, won the Nobel Prize in 1982 for his research on prostaglandins. This is the 8th time the prize has been awarded to the child of a previous winner.
    user avatar
    The Nobel Prize
    @NobelPrize
    Oct 3, 2022
    BREAKING NEWS: The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”
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    Jason Sheltzer
    @JSheltzer
    Apr 6, 2019
    I swear his chromosomes must be 80% telomere.
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    Project Big Screen
    Barstool Sports
    @ProjBigScreen
    Apr 6, 2019
    Paul Rudd turns 50 today. He’s 30 in the left photo. Nobody ages better than Paul Rudd.
  • user avatar
    Jason Sheltzer
    @JSheltzer
    Sep 11, 2019
    Our new paper is out today. We used CRISPR to uncover some really striking findings with several drugs and drug targets in clinical trials. Also, we accidentally found the first-ever inhibitor of the cyclin-dependent kinase CDK11. stm.sciencemag.org/content/11/509…
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    Jason Sheltzer
    @JSheltzer
    Aug 1, 2022
    14 years ago this month, I started as a PhD student at MIT. Here's what my entering class is doing now: