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JWeiland
@JPWeiland
Scientist. Infectious disease modeler. Tweets and spelling mistakes are my own Models and analysis seen on @Newsweek @Fortunemagazine @FaceTheNation @TIME
Joined May 2012
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    April 24th Update: We are at the lowest transmission levels in almost 5 years, 40% lower than our recent spring lows. This remarkable lull should last 6+more weeks. Estimates: 🔸90,000 new infections/day 🔸~1 in 750 currently reasonably infectious (5 day window)
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    Omicron is likely the **Fastest spreading disease known to man** Conservatively, Rt =5 But what about measles in unvaxed population at R0=15?? Its all about generation time. Measles is 15 days, Omicron is <5 60 days after 1 case: Measles: 50,600 Omicron: 244,000,000
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    Ok, this is actually concerning. The sequence of the hospitalized teen with H5N1 has been released. Both of these mutation sites are known to impact α2,6 binding that is needed for human to human transmissibility. Need top experts on H5N1 to immediately to look into this.
    Replying to @jbloom_lab @Nucleocapsoid and 5 others
    To add to thread linked above, human British Columbia H5 case has a HA sequence (GISAID EPI_ISL_19548836) that is ambiguous at *both* site Q226 and site E190 (H3 numbering) Both these sites play an important role in sialic acid binding specificity
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    Finding H5N1 bird flu (though presumibly inactivated via pasteurization) in the grocery store milk supply does not fill me with confidence that we have this situation under control at the moment.
    This isn't good, folks. I'm not worried about H5N1 transmission to humans (yet) but the @USDA pathetic lack of transparency, how long it took for the genomes to be released, lack of testing asymptomatic cattle...... All detracts from "confidence"
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    August 2nd update: Estimated daily infections rise to 900,000 as KP.3.1.1 nears dominance with some speed. 🔸900,000 new infections/day 🔸1 in every 37 people currently infected 🔸59% higher than 12 month avg.
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    This is the most heartbreaking thing I've read in some time💔 Poor woman has severe long covid, and her own family appeared to not appreciate the seriousness. She passed the next day from her disease. Please believe people when they tell you what they're going through.
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    July 12th update: Wow! after a week off of reporting, the CDC posted a large increase in wastewater levels, and retroactively increased earlier levels. 🔸620,000 new infections/day 🔸1 in every 54 people currently infected 🔸15% higher than 12 month avg.
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    September 8th US update: Community spread of Covid is "high", with a correction upwards last week as well. Current estimates: 🔸720,000 new infections/day 🔸1 in every 460 new people were infected today 🔸1 in every 46 people currently infected
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    Replying to @MichaelaOkla and @ElizabethRenzie
    He was a QA manager in the middle of testifying that Boeing had skirted a lot of safety measures during manufacturing.. then was found dead before the 3rd day of testimony. Friend said he was worried he would be killed and it labeled suicide. 😳
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    Something interesting is happening in New York. Cases have been flat over the past month, however hospitalizations are jumping significantly. New York has the highest BQ.1* proportions in the country, estimated at 25% of cases today by CovSpectrum
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    ⚠️This week may have been my last full update post on current infection numbers and trends. Why? The new administration may pause all public reports of federal health data from FDA, CDC, DHS, according to this article.
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    There is already evidence Metformin cuts long covid risk during infection. New study shows added benefits. Key points: 🔹️-3.6x viral load by day 10 🔹️-58% hosp risk 🔹️-32% rebound rebound 🔹️-42% LC risk Not bad for a $1/dose medication!
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    August 17th update (Biobot): US community spread is back up to "high" with an estimated 610,000 daily new infections. Similar levels in all 4 US regions. 🔸610,000 new infections/day⬆️ 🔸1 in every 550 new people were infected today 🔸1 in every 55 people currently infected
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    August 9th update: Estimated daily infections reach 1 million. Remarkable infection rates for a summer surge. Only BA.2->BA.5 was higher in the 2022 summer. 🔸1,000,000 new infections/day 🔸1 in every 33 people currently infected 🔸74% higher than 12 month avg.