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Hans Clevers
@HansClevers
Professor Molecular Genetics, PI at Hubrecht Institute and Princess Máxima Center, Utrecht NL. Director of Institute of Human Biology of pRED, Roche, Basel CH
Utrecht NL: Basel CH.
Joined June 2013
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    Entered my first academic lab in 1978. Fond memories of >40 years in science with great colleagues at public institutions in Kenya, the US and in my country, the Netherlands. Excited to step into the pharma world as head of research/early development at Roche, Basel in March
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    Today I start my new role @Roche as Head of pRED. Excited to take on this new challenge and work alongside brilliant people to translate #science into revolutionary medicines that can change patients’ lives. #Innovation #Research
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    Looking for PhD students/postdocs for my newly opened lab at the Institute of Human Biology of #Roche in Basel. We work on human lung, liver and gut #organoids. Send email + CV + motivation letter to [email protected] with header #IHB institutehumanbiology.com
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    A bispecific #antibody which distinguishes #cancer cells from healthy cells, doesn't care about #KRAS mutations & was developed entirely on human cancer #organoids. In 3 years from drawing board to clinic. Congrats to all collaborators. Read: rdcu.be/cL4xS
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    Growing human tear gland #organoids and making them cry... 😢 Done by PhD students Marie Bannier and Yorick Post in collaboration with Saskia Imhoff and ophthalmology colleagues at #UMCutrecht. See: authors.elsevier.com/a/1cl8i6tu0CeS…
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    Reptilian tissues can be grown as #organoids. See paper by Yorick Post et al in #Cell today. Snake #venom gland #organoids produce a full complement of toxins. Step towards improved treatment of #snakebite, known to kill 100,000 people yearly?
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    First-in-man clinical trial in post-radiation cancer patients with dry mouth and consequent severe damage to the oral cavity. Transplantation with salivary gland #organoids, developed by Rob Coppes c.s. at UMCG Groningen, Netherlands. Starts this summer!
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    Today we announce Roche's Institute of Human Biology in Basel, a bridge between academia and industry. #TeamIHB will develop and validate #organoid technology for every step of drug development at pRED & beyond to improve patient outcomes. institutehumanbiology.com @IHB_Research
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    great imaging of #snakevenom gland #organoids by Ravian van Ineveld and Anne Rios at the Princess Maxima Center in Utrecht, NL
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    A must-read for anyone interested in stem cells. And this includes myself, because Christine, Anja and Bernard did all the hard work
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    Patient-derived #cancer #organoids hold great promise for personalized medicine. Here, Else Driehuis and Kai Kretzschmar describe how to establish (cancer) organoids and how to test their in vitro sensitivity to anti-cancer therapy rdcu.be/b7N57
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    Astonishing breakthrough in #organoid engineering, as reported in @Nature by T Recaldin,M Harter,L Steinacher,B Gjeta, and colleagues: intestinal epithelial organoids incorporating tissue-resident immune cells. @IHB_Research @Roche
    Exciting new inroads into human biology and therapy development: Human intestinal organoids with an autologous tissue-resident immune compartment! #Gjorevski #Cabon #IHB @Nature @IHB_Research nature.com/articles/s4158…
    GIF
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    #ibiology recorded three lectures of 20 minutes each covering 30 years or research in my lab. They can be viewed at: ibiology.org/development-an… #stemcells #organoids @coloncancer
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    Better late than never. Bell tied around neck, and -after a long winter- finally outside! Morgins, CH. 6-6-20
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