Entered my first academic lab in 1978. Fond memories of >40 years in science with great colleagues at public institutions in Kenya, the US and in my country, the Netherlands. Excited to step into the pharma world as head of research/early development at Roche, Basel in March
Hans Clevers
544 posts
Professor Molecular Genetics, PI at Hubrecht Institute and Princess Máxima Center, Utrecht NL. Director of Institute of Human Biology of pRED, Roche, Basel CH
- Today I start my new role @Roche as Head of pRED. Excited to take on this new challenge and work alongside brilliant people to translate #science into revolutionary medicines that can change patients’ lives. #Innovation #Research
- Looking for PhD students/postdocs for my newly opened lab at the Institute of Human Biology of #Roche in Basel. We work on human lung, liver and gut #organoids. Send email + CV + motivation letter to [email protected] with header #IHB institutehumanbiology.com
- A bispecific #antibody which distinguishes #cancer cells from healthy cells, doesn't care about #KRAS mutations & was developed entirely on human cancer #organoids. In 3 years from drawing board to clinic. Congrats to all collaborators. Read: rdcu.be/cL4xS
- Growing human tear gland #organoids and making them cry... 😢 Done by PhD students Marie Bannier and Yorick Post in collaboration with Saskia Imhoff and ophthalmology colleagues at #UMCutrecht. See: authors.elsevier.com/a/1cl8i6tu0CeS…
- Reptilian tissues can be grown as #organoids. See paper by Yorick Post et al in #Cell today. Snake #venom gland #organoids produce a full complement of toxins. Step towards improved treatment of #snakebite, known to kill 100,000 people yearly?
- First-in-man clinical trial in post-radiation cancer patients with dry mouth and consequent severe damage to the oral cavity. Transplantation with salivary gland #organoids, developed by Rob Coppes c.s. at UMCG Groningen, Netherlands. Starts this summer!
- Today we announce Roche's Institute of Human Biology in Basel, a bridge between academia and industry. #TeamIHB will develop and validate #organoid technology for every step of drug development at pRED & beyond to improve patient outcomes. institutehumanbiology.com @IHB_Research
- great imaging of #snakevenom gland #organoids by Ravian van Ineveld and Anne Rios at the Princess Maxima Center in Utrecht, NL
00:00 - A must-read for anyone interested in stem cells. And this includes myself, because Christine, Anja and Bernard did all the hard work
- Patient-derived #cancer #organoids hold great promise for personalized medicine. Here, Else Driehuis and Kai Kretzschmar describe how to establish (cancer) organoids and how to test their in vitro sensitivity to anti-cancer therapy rdcu.be/b7N57
- Astonishing breakthrough in #organoid engineering, as reported in @Nature by T Recaldin,M Harter,L Steinacher,B Gjeta, and colleagues: intestinal epithelial organoids incorporating tissue-resident immune cells. @IHB_Research @RocheExciting new inroads into human biology and therapy development: Human intestinal organoids with an autologous tissue-resident immune compartment! #Gjorevski #Cabon #IHB @Nature @IHB_Research nature.com/articles/s4158…
GIF - #ibiology recorded three lectures of 20 minutes each covering 30 years or research in my lab. They can be viewed at: ibiology.org/development-an… #stemcells #organoids @coloncancer
00:00 - Better late than never. Bell tied around neck, and -after a long winter- finally outside! Morgins, CH. 6-6-20
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