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Marat Fudim, MD MHS
@FudimMarat
Duke Cardiology, 🇺🇦+🇩🇪+🇺🇸, #HeartFailure. Views expressed are my own and do not reflect the views or opinions of my employer.
Durham, NC
Joined April 2016
Posts
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    ‼️Reduction in cerebral blood flow (CBF) is found in various forms of #Dysautonomia and leads to a broad spectrum of symptoms such as dizziness, fatigue, shortness of breath, all the way out to syncope. Yet, CBF is often not monitored. pubmed.ncbi.nlm.nih.gov/27525257/
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    🔥🚨Pressures Do Not Equal Volumes🚨 #1 We present ➡️ Discordance of Pressure and Volume: Potential Implications for Pressure-Guided Remote Monitoring in Heart Failure ➡️We explored pressure-volume relationship in ambulatory HF pts. managed with CardioMEMS onlinejcf.com/article/S1071-…
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    I am a cardiologist, and my work place is above the diaphragm?! Why should I care about the #liver and #NAFLD (non-alcoholic fatty liver disease)? ⚡️Our therapies in many cases reach well beyond the heart ⚡️In order to improve outcomes we have to tackle comorbidities A🧵
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    Initiation of #SGLT2i in patients w/ acute heart failure (in-hospital or within 3 days of discharge): yes or no?   📍48%⬇️odds of rehospitalization for HF 📍Improvement in KCCQ 📍No⬆️risk of AKI, hypotension, or hypoglycemia   Meta-analysis by @HusamSalah tinyurl.com/4fewmkbp
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    Can NAFLD drive some HFpEF phenotypes? Check out our review in @JACCJournals in which we propose 3 NAFLD-related HFpEF phenotypes: obstructive HFpEF, metabolic HFpEF/NAFLD, and advanced liver disease/cirrhosis HFpEF. bit.ly/3cCWPdh
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    🚨Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week We discuss the contribution of the vascular system, in particular the often neglected veins to the modulation of blood volume in health and disease @JACCJournals jacc.org/doi/10.1016/j.…
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    🚨Very excited to report the 1st US case of Pulmonary Arterial Denervation🫁for heart failure♥️ and preserved ejection fraction (HFpEF) and high pulmonary vascular resistance (PVR) using the Gradient System. Desperate need for therapies. Big team effort! classic.clinicaltrials.gov/ct2/show/NCT06…
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    The landscape of device based therapies in heart failure has seen a major shift in the last years. This is in parts due to a change in the regulatory environment. Our review covers devices for chronic HF, approved and in the pipeline: sciencedirect.com/science/articl… @JACCJournals
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    thelancet.com/journals/lance… Largest device trial in HFpEF is out. Placement of an atrial shunt device did not reduce the total rate of heart failure events or improve health status in the overall population of patients with heart failure and ejection fraction of 40+
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    #1 Cuff-less blood pressure monitors will change the way we monitor blood pressure and treat hypertension ⚡️Think of the shear amount of information that will come our way when patients/medical teams gain access to beat by beat, minute by minute blood pressure data, 24/7, 365
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    Breakthrough results for Jardiance® (empagliflozin) confirm EMPEROR-Preserved as first and only successful trial for heart failure with preserved ejection fraction Finally we got a winner for HFpEF.
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    🧵 #1 The lymphatic system has been suggested as a key player in the pathophysiology of heart failure. Lymphatic vessels drain fluid and prevent tissue edema. Daily ~3L are drained back into the venous system. sciencedirect.com/science/articl…
    What is the relationship between lymphatic system (LS) function and signs of congestion in AHF? We used the VEGF-C (as a proxy of LS) and analysed its' relation with several clincal signs of congestion and mortality in AHF onlinejcf.com/article/S1071-…
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    1. "Heart" Failure is not only a problem of the heart. The ability to modulate preload (aka Preload Reserve) is central to activity/exercise. Find the review on ⚡️Extracardiac Abnormalities of Preload Reserve in HFpEF⚡️ @sobotka_paul MarkDunlap @CircHF ahajournals.org/doi/full/10.11…
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