Caitlyn Vlasschaert (@DrFlashHeart) / X

Caitlyn Vlasschaert

4,797 posts

Caitlyn Vlasschaert

@DrFlashHeart

MD/PhD • Nephrology, genetics, and clonal hematopoiesis 🧬

Queen's University – Canada

scholar.google.ca/citations?user…

Joined April 2012

Pinned
Caitlyn Vlasschaert
@DrFlashHeart
Aug 13, 2020
“What is the role of vasopressin?” A nephrologist will talk about osmolality and aquaporins. An intensivist might talk about its use as a pressor. But, ask an evolutionary or social scientist and you might be surprised by the answer… #MedTwitter #NephTwitter #NSMC
Caitlyn Vlasschaert
@DrFlashHeart
Aug 13, 2020
Replying to @DrFlashHeart
So, what is the role of vasopressin? An evolutionary scientist will say its adaptations helped our transition from water to land. A social scientist might say it helps us socialize. I’d say: vasopressin has allowed us to become human.
Caitlyn Vlasschaert
@DrFlashHeart
Oct 13, 2021
✨Introducing: A 1-minute review of lupus nephritis As a trainee, I've found it hard to wrap my head around the many classes and emerging treatment options in LN. Mithu (@MithuRheum) and I created this short audiovisual primer on LN. 🐺 youtu.be/hBZ_X3J3hDA #NephTwitter
00:00
Caitlyn Vlasschaert
@DrFlashHeart
Aug 13, 2020
Replying to @DrFlashHeart
Thanks in part to ADH, kidneys can effectively concentrate urine to meet a range of homeostatic needs. Or, in the words of Homer W. Smith… (Read a reprint of his classic text here: anatomypubs.onlinelibrary.wiley.com/doi/epdf/10.10…)
Caitlyn Vlasschaert
@DrFlashHeart
Jan 18, 2023
Our paper demonstrating an approach to CHIP curation in large datasets is now out in Blood (@BloodJournal)! 🩸 We identify CHIP in >500,000 individuals and show how common challenges such as sequencing artifacts and germline variants can be addressed. ashpublications.org/blood/article-…
60K
Caitlyn Vlasschaert
@DrFlashHeart
May 1, 2023
Passed my PhD defence [while 7.5 months pregnant!] ✅ Thankful to the mentors and collaborators who helped me reach this milestone, including Mike (@QMyPath), Matt (@MattLanktree), Alex (@AlexBickMDPhD), Cassy (@CassyRCohen) and many others!
50K
Caitlyn Vlasschaert
@DrFlashHeart
Mar 16, 2022
Hi everyone! March is the best month of the year because of #NephMadness. So thrilled to join this special #NephJC to discuss this year's topics. COI(-ish): co-wrote the Cardiorenal region with @ssfarouk @anna_burgner @HeartDocSadiya @NishaKidneyDoc ajkdblog.org/2022/03/01/nep…
Caitlyn Vlasschaert
@DrFlashHeart
Nov 4, 2023
Grateful that ASN #KidneyWk is being held in a facility that makes it a bit easier to care for my 4-month old while enjoying the conference.
17K
Caitlyn Vlasschaert
@DrFlashHeart
Mar 30, 2021
SGLT2 inhibitors in CKD and heart failure: ready for prime time in patients without diabetes New review article written by Drs. Sam Silver (@drsamsilver), Bikrampal Sidhu (@bsidhu28) and I for an upcoming issue of CONH. journals.lww.com/co-nephrolhype… #NephTwitter #flozination
Caitlyn Vlasschaert
@DrFlashHeart
Nov 14, 2023
PhD girlies ✨
Caitlyn Vlasschaert
@DrFlashHeart
May 1, 2023
Passed my PhD defence [while 7.5 months pregnant!] ✅ Thankful to the mentors and collaborators who helped me reach this milestone, including Mike (@QMyPath), Matt (@MattLanktree), Alex (@AlexBickMDPhD), Cassy (@CassyRCohen) and many others!
15K
Caitlyn Vlasschaert
@DrFlashHeart
Aug 13, 2020
Replying to @DrFlashHeart
Nope: it’s oxytocin. Oxytocin & vasopressin are evolutionary cousins located side-by-side on human chromosome 20. Invertebrates have one hybrid copy. Tandem duplication in the common jawed vertebrate ancestor gave rise to our two gene copies. Image from science.sciencemag.org/content/322/59….
Caitlyn Vlasschaert
@DrFlashHeart
Jun 28, 2020
Unlike most other animals, humans cannot convert uric acid into a more soluble compound. Precipitated uric acid can cause a host of problems like gout and kidney stones. What happened to our uricase?: a brief Tweetorial. Fig. from pnas.org/content/111/10… #NephJC #NephTwitter
Caitlyn Vlasschaert
@DrFlashHeart
Aug 13, 2020
Replying to @DrFlashHeart
Vasopressin and oxytocin signalling in the brain regulates social behaviour in many species. In humans, genetic variants in these receptors (particularly in the V1a receptor, AVPR1A) appear to contribute to sociobehavioral diversity. More on this here: science.sciencemag.org/content/322/59…
Caitlyn Vlasschaert
@DrFlashHeart
Apr 24, 2019
Visual summary of the epic CREDENCE #NephJC hosted last night by @hswapnil.