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biohub
5,972 posts
biohub
@biohub
Combining frontier AI & frontier biology to help scientists cure or prevent disease
Joined June 2017
- biohub reposted
Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in
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A new era of science is here — and it starts with the integration of frontier AI and frontier biology. Priscilla Chan, Mark Zuckerberg, and @alexrives sat down with @NoPriorsPod to talk about the progress we’re making at Biohub and what comes next.
00:00- biohub reposted
new @NoPriorsPod with Priscilla Chan, Mark Zuckerburg and Alex Rives: - taking seriously the @biohub mission to cure and prevent all disease (soon!) - Model release of ESMFold2 and ESM Atlas (beating AlphaFold) - new biological knowledge from the models - ecosystem strategy
00:00 - biohub reposted
Mark Zuckerberg wanted to cure, prevent, and manage all diseases by the end of the century. He and Priscilla then had a series of meetings where Nobel Prize-winning scientists laughed at them. Now Zuckerberg says, "I thought that by the end of the century was a stretch. Now I
00:00 - ESM Atlas doesn't just store proteins, it understands them. Ask about one and the agent reasons over roughly 16,000 interpretable biological features learned from evolution, surfacing connections that sequence similarity alone would never reveal. You don't look proteins up. You
- biohub reposted
Helping write "the book of life" 📖 Nonprofit research institute @biohub has unveiled the next-generation ESM—a new suite of #AI tools designed to model protein biology. Northwestern's @ShanaOKelley is the organization’s president of bioengineering. - Dubbed a “Swiss army knife” for biological imaging, MOSAIC’s development was led by Biohub Investigator Gokul Upadhyayula of @ABCUCBerkeley. Learn more about the microscope, and the “AI mind” he’s creating to make sense of all the data:MOSAIC: a versatile multimodal microscopy that seamlessly transitions between light-sheet, 2-photon, label-free and super-resolution modalities. @Eric_Betzig @ABCUCBerkeley @legant_lab nature.com/articles/s4159…
- biohub reposted
Our paper on ESMC, ESMFold2, and mechanistic interpretability for proteins is up on @biorxivpreprint! We've made a few changes since the initial version went online last week. 1. We found an issue in the way we provided MSAs to OpenFold3. This led us to report lower performance - biohub reposted
Excellent and timely article, we got into a lot of this at the recent @biohub symposium. What excites me about new AI capabilities paired with scalable/lower cost measurement modalities is how much they lower the barrier to capturing context, from tracking more dimensions ofThe training data market has exploded for LLMs and bio foundation models are next. But biological data is extremely complex and requires a data generation playbook that prioritizes quality over immediate scale. @_DimensionCap Research article live now! research.dimensioncap.com/p/on-training-…
- ESMC didn't learn protein biology from a textbook. It learned from 2.8 billion sequences—the full evolutionary record of what works in nature. That's what a world model of protein biology looks like. Download the model and start building: bit.ly/4ebUoxY
