Investing in Tomorrow’s World-Changers.
Investing in Tomorrow’s World-Changers.
Our Approach
Investing in technology companies developed at the leading universities of the world
Safar™ has deep connections to world-class universities — primarily, MIT, Harvard, and the University of Rochester — to invest in the commercial potential of technology startups originating there. As board members, trustees, and partners of these three institutions, Safar’s principals have had a long and successful history of investing in innovative entrepreneurs and tech startups, an approach that they have now institutionalized at Safar. Founded in 2018, Safar has invested in 75+ portfolio companies and has over $1B under management.
Safar invests in three areas: cleantech and advanced materials, AI/IT and robotics, and life sciences. Safar targets a return multiple of over 4x on invested capital and a net IRR of over 20%.
University Relationships
Deep roots at leading academic institutions.
Our board is comprised of scholars and experts from Harvard, MIT, and the University of Rochester who are committed to seeing a more efficient technology transfer and faster scaling of ideas that will change the world.
“Working with Safar has been a pleasure – they have been engaged, and were willing to try our product, for which no previous frame of reference existed. Safar is willing to take leaps, shift paradigms, and nurture disruptive technology, and we are thrilled to be part of their portfolio.”
Sharon Samjitsingh
Co-Founder, Health Care Originals
Our Mission
Creating value through innovation.
With the vision and global reach to tackle today’s biggest challenges, including climate change and global health, Safar nurtures innovations in sustainable energy, clean water, food management, and healthcare to maximize returns and create impact.
Safar has made a public commitment to formally incorporate considerations of environmental, social, and governance factors into its investment processes (https://safar.partners/esg-policy) and is a signatory to the United Nations-backed Principles for Responsible Investment. Accordingly, Safar publishes an annual sustainability report covering all our investments (Link).
Investment Strategy
Uniquely positioned, our flexible strategy allows us to take technologies from inception to global scale.
Early Stage Investment
Flexible model
A network of experts
“Over the years that I have known Safar principals, I have seen them be early supporters of world changing technologies. I’m excited about continuing to build the next generation of PSFC startups with the team and grateful for their continued support.”
Dennis Whyte
Former Director, Plasma Science and Fusion Center at MIT and Hitachi America Professor of Engineering at MIT
Our Team
From industry veterans with decades of experience to fresh minds with a drive to change the world, our diverse team is committed to guiding our portfolio companies to financial success and global impact.
Nader Motamedy
Arunas Chesonis
Sahba Vaziri
Partner, CFO, Investment Committee Member
Nader Motamedy is a Founder and Managing Partner at Safar Partners, an early-stage technology investment platform with over $1 billion of committed capital. Nader serves on the Board of Aramis Biosciences, The Turing Company, and is a Board Observer and Senior Advisor to the CEO on Finance at Commonwealth Fusion Systems and Gradiant Corp.
Prior to founding Safar in 2018, Nader was Senior Founding Partner, Chairman, and CEO of Caspian Private Equity, with over $3 billion under management. Prior to that, Nader was a Founding Partner and member of the Board of Managers of Caspian Capital Management which managed over $5 billion of alternative assets, including fixed income relative value portfolios and quantitative trading strategies. Nader began his investment career at Morgan Stanley in 1985 and worked at Prudential Securities and CDC Investment Management Corporation.
Nader holds an MBA from Boston College and a BS in Mechanical Engineering from Boston University. In addition to other community engagements, he is also actively involved in several youth assistance and development projects. Nader was instrumental in establishing the Paris St. Germain professional soccer team youth development program and its Foundation in the United States to help underprivileged youth achieve their athletic as well as academic potential. He is also a senior advisor to Inter Campus, the philanthropic arm of Inter Milan soccer team in New York as well as the Youri Djorkaeff Foundation. Nader is a member of the Directors Council at the Whitney Museum of Art. He is also a member of the Tiger 21 organization in Boston, MA.
Arunas Chesonis is a Managing Partner at Safar Partners. He has a long history in sustainability and has supported numerous environmental and renewable energy research projects at the Massachusetts Institute of Technology to address climate change. He has also personally invested in the past 15 years in cleantech, life sciences, and information technology ventures through his involvement at universities in Boston and Rochester. Arunas served as CEO of Sweetwater Energy and prior to that, he served as Chairman and Chief Executive Officer of PAETEC Holding Corp., a Fortune 1000 telecommunications company acquired in 2011 by Windstream Corp. (NASDAQ: WIN), one of the largest national telecom carriers. Arunas founded PAETEC in 1998.
He holds a B.S. in Civil Engineering from MIT, an MBA from the William E. Simon Graduate School of Business at the University of Rochester, and an Honorary Doctorate of Laws from the University of Rochester. Arunas is also a member of the M.I.T. Corporation and is a life trustee of the University of Rochester.
Sahba Vaziri is a Partner, the Chief Financial Officer and member of the Investment Committee at Safar Partners. Sahba also spearheads the ESG efforts at Safar Partners..
Sahba is a successful finance professional in the energy field, focusing on renewable energy. She has 20 years of experience financing power projects, both as a banker at Lehman Brothers, CS First Boston Corporation, and Bechtel Corporation, and as a personal investor. Most recently, Sahba worked as a financial consultant to the leading marine hydrokinetic energy company, Ocean Renewable Power Company, where she analyzed financial and market conditions, performed due diligence, and raised private and public financing.
Sahba is a dual degree holder from MIT. She received her MBA from Sloan School of Management, with Concentrations in Finance and International Management. She also has a BSc in Electric Engineering from MIT with concentrations in Optoelectronics and Telecommunications. Sahba is involved with community volunteering, as a member of the Ethel Walker School Board of Trustees, and a member of Mission: Restore Advisory Board.
Greg S. Feldman
Partner, Investment Committee Member
Bob Millard
Senior Advisor, Chairman Emeritus of MIT Corporation
Robert Metcalfe, Ph.D.
Senior Advisor & MIT Corporation Life Member Emeritus
Ayman Hindy, Ph.D.
Senior Advisor
Greg Feldman is a Partner and a member of the Investment Committee. He recently retired from Wellspring Capital, a New York-based private equity firm, which he co-founded in 1995.
Greg has served on the boards of more than twenty public and private companies. In addition to his for-profit board activities, Greg has served as President of the Board of The Kitchen and Co-Head of the Director’s Council at The Whitney Museum of American Art. Greg received a Bachelor of Arts degree from Hampshire College and a JD from the Benjamin N. Cardozo School of Law, where he was Editor-in-Chief of the Law Review. Greg and his wife have three children and live in New York City.
Bob Metcalfe received the 2022 Turing Award for inventing, standardizing, and commercializing Ethernet, plumbing for the Internet on June 10, 2023. The Turing Award comes with a million-dollar Prize and is often called the Nobel in Computer Science.
Metcalfe’s grandparents arrived from Norway, England, and Ireland in New York City about 100 years ago. They met and married in Brooklyn. Bob was born and raised on Long Island.
Bob became an Internet pioneer starting in 1970 at MIT, Harvard, Xerox Parc, Stanford, and his Silicon Valley startup, 3Com Corporation. He invented Ethernet at the Xerox Palo Alto Research Center (Parc) in 1973, 50 years ago, to connect personal computers to the Internet. He founded 3Com in 1979 to promote computer communication compatibility. 3Com went public in 1984 and became a billion-dollar part of HP in 2010.
Bob is now starting his sixth career. He was an engineer-scientist, entrepreneur-executive, publisher-pundit, venture capitalist, and professor of innovation. He is now Emeritus Professor of Electrical and Computer Engineering at The University of Texas at Austin. He has started as a Research Affiliate at his alma mater MIT. Bob is now a fledgling computational engineer. He is currently modelling geothermal wells.
Metcalfe graduated from the Massachusetts Institute of Technology in 1969, receiving two Bachelor of Science degrees in electrical engineering and industrial management. He then attended Harvard University and received a Master of Science in Applied Mathematics in 1970 and a PhD in Computer Science in 1973.
Robert B. Millard is the Chairman Emeritus of the MIT Corporation and a Senior Advisor to Safar Partners. He is also a member of the Council on Foreign Relations and serves on the External Advisory Council of NYU’s Global Institute for Advanced Study, the Business Advisory Board of Safar Partners, and the MIT Dean of Science Advisory Council. He attended MIT as an undergraduate and holds an MBA from Harvard Business School. He was elected to the MIT Corporation in 2003 and became the 11th Chairman of the Corporation in 2014. He has been a member of the Visiting Committees for Physics, Architecture, Chemistry, and Philosophy & Linguistics. He also served as the Chairman of MITIMCo, which manages MIT’s endowment. He is co-founder and former Chairman of the Board of L3 Technologies, a major defense technology company. He currently serves as Lead Director of L3Harris Technologies. He is a Director of Evercore, an international investment bank, and a former Partner of Lehman Brothers. In addition, he is a fellow of the American Academy of Arts & Sciences and a board member of the American Association for the Advancement of Science (AAAS). He is married to Bethany Millard and has four children. He lives in Miami and New York.
Ayman Hindy is a Senior Advisor to Safar Partners. He is a managing director in PIMCO’s Newport Beach office, overseeing portfolio management reengineering and infrastructure. He focuses on the oversight of portfolio management processes, technology, and execution. Prior to joining PIMCO in 2021, he was an operating partner at Safar Partners, and previously he was a partner at Advanced Liquidity Concepts, an investment firm specializing in execution efficiency. Prior to this, he was a partner, senior portfolio manager, and head of the U.S. office for Capula Investment Management, and a founding partner and portfolio manager at Platinum Grove Asset Management. He has served as a professor of finance at the Graduate School of Business at Stanford University and published research in leading academic journals, and he is a guest lecturer at leading business schools. He served on the advisory board of the Cairo Stock Exchange and the visiting committee at the American University in Cairo. He has 28 years of investment experience and holds a master’s degree in engineering and a Ph.D. in financial economics from the MIT.
Piyush Bharti
Operating Partner
Tim Bowe
COO and Head of Operating Partners
Rob Fleischman
Operating Partner
Roberta Sydney
Operating Partner
Piyush Bharti served as the head of the Americas at Capula Investment Management, where he was also a member of the Board of Partners and a senior portfolio manager. Prior to that, he managed the research department at Enuvis, a startup that created algorithms for assisted GPS in mobile devices before it was acquired. Piyush holds a Master’s in Electrical Engineering and Computer Science, specializing in communications, as well as bachelor’s degrees in EECS and finance from MIT
In addition to his professional endeavors, Piyush cherishes spending time with his family. He also enjoys spending time on the water, snowboarding, and playing tennis.
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Tim Bowe is an Operating Partner of Safar Partners and has more than 40 years starting, leading and investing in technology startup companies. With deep product development experience in medical devices and healthcare systems, semiconductor and capital equipment automation, green technologies, aerospace and technical product development services; he is a seasoned executive currently sitting on the board of multiple companies working across a variety of these industries.
Tim has spent his career in the development and productization of novel technologies and has been a founder or principal in nearly a dozen startups. His corporate operating experience includes CEO and executive management roles with many of these startups, as well as serving as Executive Vice President, Americas and Asia and member of the Executive Committee for Altran Technologies (subsequently acquired by Cap Gemini), the largest engineering R&D company in the world. In this position Tim was responsible for all operations outside of Europe, consisting of more than 3,000 engineers across North America, China and India. Prior to this role, Tim was the co-founder and CEO of Foliage, a globally recognized leader in the development of technology-based products, along with industry-leading technology consulting services, successfully overseeing its growth to more than 500 engineers globally.
Rob Fleischman is an Operating Partner of Safar Partners and a successful technology entrepreneur and has deep knowledge in the areas of Internet Infrastructure, Distributed Systems, Artificial Intelligence, Security, Networking, and Very Large Scale Server Development. After graduating from MIT (SB in Computer Science, SM in Computer Science and Electrical Engineering), Rob began his career at BBN Labs (where the Internet was invented, in fact, Rob’s first mentor was Ray Tomlinson, the inventor of e-mail). Mr. Fleischman founded multiple start-ups, and held senior engineering positions at large technology and financial companies (BBN, Fidelity, Highwind, Software.com, Openwave, Sandvine, Xerocole, Akamai, and others). He holds many patents, invented and helped build news, messaging and DNS technologies that currently process trillions of transactions daily on the Internet.
Mr. Fleischman is currently a valued advisor on the boards of multiple technology companies and leads multiple endowment investment committees. In addition, Rob is currently a Tiger 21 chair in Boston where he helps UHNW investors, families, and financial advisors discuss investments, family wealth issues, and philanthropy.
For many years, for fun, Rob could be heard on the radio as a guest and contributor to NPR in New England as the “explainer of all things wired”. Finally, and most importantly, Rob is a dedicated husband and father (2 daughters) and works hard to maintain an active life in New Hampshire.
Roberta Sydney is an Operating Partner of Safar Partners and a seasoned board director and former CEO serving on private and public boards. She has deep expertise in the areas of financial services, construction, real estate technology, real estate development and operations.
Ms. Sydney is currently a valued board member of multiple prop-tech, construction and real estate companies and serves on the investment committee of a large single-family office.
Her board experience includes service as board chair, lead independent director, and as chair of audit, compensation and nominating/governance committees. In her board career, she has helped companies go public, and complete M&A transactions along with successful integrations.
Her corporate operating experience includes senior roles with financial services and money management institutions, including State Street Global Advisors, BayBank, and the Boston Company, before founding, growing, developing, and managing 9 million square feet and successfully exiting her own commercial real estate development company.
Ms. Sydney received a bachelor’s from Wellesley College, an MBA from Harvard Business School, and a Master’s in Real Estate from MIT. She was named a Private Company Director to Watch in 2020. Along with her professional pursuits, she is active philanthropically, loves to spend time with her family, watch wrestling, and try to improve her golf game.
Vera Schroeder, Ph.D.
Partner & Investment Committee Member
Parinaz Motamedy
Partner & Investment Committee Member
Arda Kotikian, Ph.D.
Harvard PhD and Associate
Leslie Hartford
Manager of Administration
Parinaz Motamedy is a Partner and Investment Committee Member at Safar Partners. Prior to joining Safar, Parinaz worked at Accorhotels in Paris, investing in hospitality startups on Accor’s corporate venture team. Before Accor, Parinaz worked on the Product Structuring Team at Blackstone, structuring specialized hedge fund products at Blackstone Alternative Asset Management in New York City. Parinaz holds an MBA from MIT Sloan, and a BA in Philosophy and a secondary in Psychology from Harvard University.
Vera Schroeder is a Partner and Investment Committee Member at Safar Partners. Vera brings broad experience in the fields of chemistry, nanoscience and materials science to the Safar team. As a graduate student, she worked in the laboratory of Professor Tim Swager at MIT focused on carbon-nanotube based chemical sensing. While at MIT, she also spent her time at Sloan and HBX learning about venture creation and strategy as well as interning at MP Healthcare Venture Management fund. She holds a BS and MS in Chemistry from RWTH Aachen University and a Ph.D. in Chemistry from MIT.
Arda Kotikian is an Associate at Safar Partners. Prior to joining Safar, Arda was a postdoctoral fellow and completed a PhD at Harvard University in the lab of Jennifer Lewis. During her graduate studies and postdoctoral work, she worked on developing new materials and additive manufacturing methods for soft robotic, soft electronic, and bio applications. Arda holds a Ph.D. in Mechanical Engineering and Materials Science from Harvard and a B.A. in Chemistry and Mathematics from Mount Holyoke College.
Leslie Hartford is the Manager of Administration at Safar Partners. She brings extensive experience in executive, financial and legal administration to the Safar team. Leslie has over 20 years of experience working directly with corporate executive and legal teams at AIG, Inc., PAETEC Corp., and Sweetwater Energy, Inc. She holds a BA in Sociology from Le Moyne College, a Paralegal Certification from Syracuse University, and a MBA from the Madden School of Business at Le Moyne College.
Tony Cheung
Manager of Systems & Operations
Hannah Jacobs, Ph.D.
MIT PhD and Associate
Andy Cohen, Ph.D.
Harvard PhD and Associate
Tony Cheung is the Manager of Systems and Operations. Since 2013, he has consulted for various private equity firms, hedge funds, and startups primarily advising and implementing information technology, operations, and business processes. Prior to that, he worked as a Trade Analyst at Caspian Capital Management, which managed as much as $2.2 billion of alternative assets. Tony holds a B.S. in Information Technology from Rensselaer Polytechnic Institute.
Hannah Jacobs is an Associate at Safar Partners. Hannah holds a PhD from MIT in Biology. Her MIT graduate research in Chris Burge’s lab and at the Broad Institute focused on developing computational tools to better understand human variation at the genetic and RNA level. While at MIT she worked on healthcare venture creation with MIT Hacking Medicine and was an analyst at Safar. She holds a B.A. in Biochemistry from Wellesley College.
Andy Cohen is an Associate Partner at Safar Partners. He completed his PhD at Harvard’s Microrobotics Lab, where he developed practical manufacturing techniques for industrial-scale production of soft artificial muscles. In his postdoctoral studies at Harvard, he investigated the medical and consumer electronics applications of these muscles. He also holds a B.S. in mechanical engineering from Virginia Tech.
“The Safar team is highly experienced and knows how to provide the right resources and guidance at the right time and stage, evolving with us. Safar is not just a capital backer – they are a true partner investing in Pirouette’s success“
Conor Cullinane
Co-Founder, Pirouette Pharma
Scientific Advisory Board
Influential academic leaders dedicated to advancing new technologies.
Danielle Benoit
University of Oregon
Lorry Lokey Chair of the Department of Bioengineering
Markus J. Buehler
MIT
Former Department Head of Civil and Environmental Engineering & McAfee Professor of Engineering
Vladimir Bulović
MIT
Director of MIT.nano, Professor of Engineering at MIT and Fariborz Maseeh Chair in Emerging Technology
Michael J Cima
MIT
David H. Koch Professor of Engineering and Faculty Director of the Lemelson MIT Program
Danielle Benoit is the inaugural Lorry Lokey Chair of the Department of Bioengineering. Her research specializes in the rational design of polymeric materials for regenerative medicine and drug delivery applications. Dr. Benoit’s work has provided insights into the translation of tissue engineering strategies for bone allograft repair, development of pH-responsive nanoparticles for nucleic acid and small molecule delivery, and novel targeting strategies for bone-specific delivery of therapeutics.
Benoit received her Ph.D. from the University of Colorado and completed her postdoctoral fellowship at the University of Washington in the Department of Bioengineering. She holds a B.S. from the University of Maine, Orono, in Biological Engineering.
Before joining the Knight Campus, Benoit served as the University of Rochester’s William R. Kenan, Jr. Distinguished Professor in the Department of Biomedical Engineering and Director of the Materials Science Program. An award-winning researcher, teacher, and mentor, she is a fellow of the American Institute of Medical and Biological Engineering and is an Associate Editor for Science Advances and the Journal of Biomedical Materials Research Part B.
As chair, Benoit plays an instrumental role in continued development of the Department of Bioengineering, including shaping and maturing the research and educational portfolio, coordinating fundraising, outreach, and alumni and industry relations, and hiring of approximately 15 new faculty as Phase 2 of the Knight Campus is completed. These efforts will be critical to advancing the Knight Campus mission of translating research discoveries into innovations to improve the human condition.
Markus J. Buehler is Former Department Head of Civil and Environmental Engineering & McAfee Professor of Engineering at MIT. He also directs the Laboratory for Atomistic and Molecular Mechanics (LAMM) and serves as the Director of the MIT-Germany Program. Until 2013, he served as Co-Director of the MIT Computation for Design and Optimization Program.
Buehler has published more than 300 articles and delivered hundreds of plenary, keynote and invited speeches. Buehler received the NSF CAREER award, the United States Air Force Young Investigator Award, the Navy Young Investigator Award, and the DARPA Young Faculty Award, as well as the Presidential Early Career Award for Scientists and Engineers (PECASE). In 2010 he received the Harold E. Edgerton Faculty Achievement Award for exceptional distinction in teaching and in research or scholarship. Other awards include the TMS Hardy Award, the IEEE Holm Conference Mort Antler Lecture Award, the Materials Research Society Outstanding Young Investigator Award, the SES Young Investigator Medal, the Thomas J.R. Hughes Young Investigator Award, the Sia Nemat-Nasser Medal, the Rossiter W. Raymond Memorial Award, the Stephen Brunauer Award, the Alfred Noble Prize, and the Leonardo da Vinci Award. Buehler serves as a member of the editorial board of many international publications and has chaired numerous committees.
He received a Ph.D. in Chemistry from the University of Stuttgart and the Max Planck Institute for Metals Research after obtaining a M.S. in Engineering Mechanics from Michigan Tech, and undergraduate studies in Chemical and Process Engineering at the University of Stuttgart.
Vladimir Bulović is a Professor of Electrical Engineering at the Massachusetts Institute of Technology, holding the Fariborz Maseeh Chair in Emerging Technology. He directs the Organic and Nanostructured Electronics Laboratory, co-leads the MIT-Eni Solar Frontiers Center, leads the Tata GridEdge program, and is the Founding Director of MIT.nano, MIT’s new 200,000 sqft nano-fabrication, nano-characterization, and prototyping facility that opened in the summer of 2018. He is an author of over 250 research articles (cited over 45,000 times) and an inventor of over 100 U.S. patents in areas of light emitting diodes, lasers, photovoltaics, photodetectors, chemical sensors, programmable memories, and micro-electro machines, majority of which have been licensed and utilized by both start-up and multinational companies. The three start-up companies Bulović co-founded jointly employ over 400 people, and include Ubiquitous Energy, Inc., developing nanostructured solar technologies, Kateeva, Inc., focused on development of printed electronics, and QD Vision, Inc. (acquired in 2016) that produced quantum dot optoelectronic components. Products of these companies have been used by millions. Bulović was the first Associate Dean for Innovation of the School of Engineering and the Inaugural co-Director of MIT’s Innovation Initiative, which he co-led from 2013 to 2018. For his passion for teaching Bulović has been recognized with the MacVicar Fellowship, MIT’s highest teaching honor. He completed his Electrical Engineering B.S.E. and Ph.D. degrees at Princeton University.
Prof. Cima is author or co-author of over three hundred peer reviewed scientific publications, fifty US patents, and is a recognized expert in the field of medical devices and materials processing. Prof. Cima is actively involved in materials and engineered systems for improvement in human health such as treatments for cancer, metabolic diseases, trauma, and urological disorders. Prof. Cima’s research concerns advanced forming technology such as for complex macro and micro devices, colloid science, MEMS and other micro components for medical devices that are used for drug delivery and diagnostics, high-throughput development methods for formulations of materials and pharmaceutical formulations. He has been a major contributor to the development of high throughput systems for discovery of novel crystal forms and formulations of pharmaceuticals. Prof. Cima also has extensive entrepreneurial experience. He is co-founder of MicroChips Biotech., a developer of microelectronic based drug delivery and diagnostic systems. Prof. Cima took two sabbaticals to act as senior consultant and management team member at Transform Pharmaceuticals Inc., a company that he helped start and that was ultimately acquired by Johnson and Johnson Corporation. He is a co-founder of T2 Biosystems a medical diagnostics company. Prof. Cima is also a co-founder of Taris Biomedical a company specializing in pharmaceutical products for urology which was acquired by Johnson and Johnson in 2019. He recently founded Stratagen Bio, a radiological diagnostic company. He currently serves on several boards including GelMedix Inc. and Statagen Bio. Prof. Cima is devoted to engineering education and was the instructor in charge of 3.091 (Introduction to solid-state chemistry) from 2011 through 2014 which is a unique MIT course. He created an online version of the course that has been offered many times since 2012 as 3.091x to students world-wide over the edX platform. Tens of thousands of students have participated. He was appointed faculty director of the Lemelson-MIT Program in 2009 which is a program to inspire youth to be inventive and has a nationwide reach. Hundreds of high school students and teachers participate each year in hands on engineering design projects. He created a course 2016 on medical product development (HST.962). The course is now offered as a professional development course worldwide (MIT xPro, Drug and Medical Device Development: A Strategic Approach).
Reza Dana
Harvard Medical School, Mass. Eye and Ear
Claes Dohlman Professor of Ophthalmology at Harvard Medical School, and Director of Cornea at the Massachusetts Eye and Ear
Jeffrey Grossman
MIT
Former Department Head of Materials Science and Engineering & Morton and Claire Goulder and Family Professor in Environmental Systems
Jennifer Lewis
Harvard
Wyss Professor of Biologically Inspired Engineering
Timothy M. Swager
MIT
Former Department Head of Chemistry, Director of The Deshpande Center for Technological Innovation & Professor of Chemistry
Reza Dana is the Claes Dohlman Professor of Ophthalmology at Harvard Medical School, and Director of Cornea at the Massachusetts Eye and Ear, and Senior Scientist at the Schepens Eye Research Institute of Mass Eye and Ear, where he leads the Laboratory of Corneal Immunology, Transplantation and Regeneration. In addition, he is a faculty member of the Immunology graduate program at Harvard Medical School and Director of the Harvard-Vision Clinical Scientist Development Program.
A graduate of Johns Hopkins and Harvard, his work focuses on disease mechanisms that underlie autoimmunity, tissue scarring, transplant failure, chronic inflammation, and pathological blood vessel formation. He has authored over 400 articles and his published work has been cited more than 26,000 times. He has been recipient of numerous awards, including the Association for Research in Vision and Ophthalmology Cogan and Friedenwald Awards, the Physician-Scientist Award, Senior Investigator Award and the Stein Innovation Award from Research to Prevent Blindness, the Alcon Research Institute Award, the Endre A. Balazs Prize from the International Society of Eye Research, and the Ellis Island Medal of Honor for his contributions in the United States.
He is Editor-in-Chief of Cornea, Senior Associate Editor of Ocular Surface, and Senior Editor of Encyclopedia of the Eye. In addition to his basic investigations, he leads a translational research program that has received 12 IND permits from the US FDA. He has trained over 120 fellows and graduate students from 34 countries in his laboratory, and over 80 physician fellows to date. He is recipient of the A. Clifford Barger Excellence in Mentoring Award at Harvard Medical School.
Reza Dana has launched multiple new programs in biotechnology, and has co-founded several new enterprises including Eleven Biotherapeutics, Claris Biotherapeutics, Aramis Biosciences, and Boston Eye Diagnostics.
Jeffrey Grossman received his PhD in theoretical physics from the University of Illinois and performed postdoctoral work at the University of California at Berkeley. In 2009 he joined MIT, where he has developed a research program known for its contributions to energy conversion, energy storage, membranes, and clean-water technologies. He has published more than 200 scientific papers, holds 17 current or pending U.S. patents, and recently co-founded two Massachusetts companies to commercialize novel membranes materials for efficient industrial separations: ViaSeparations, a company that commercializes graphene-oxide membranes to separate chemicals for manufacturing, and SiTration, a company that commercializes silicon membranes for chemical-free, energy-efficient extraction and recycling of critical materials.
Jennifer Lewis is the Wyss Professor of Biologically Inspired Engineering at Harvard University. Her research focuses on creating functional, structural, and biological matter that emulates natural systems. She currently directs the Harvard Materials Research Science and Engineering Center (MRSEC) and serves as the Bioengineering Area Chair in the Paulson School of Engineering and Applied Sciences. Multiple startups are commercializing technology from her lab ranging from 3D printing to drug delivery and kidney therapeutics.
She earned her Sc.D. degree from the Department of Materials Science and Engineering at MIT. Lewis is an elected member of the National Academy of Sciences, the National Academy of Engineering, the National Academy of Inventors, and the American Academy of Arts and Sciences.
Swager earned his B.S. in Chemistry from Montana State University, received a Ph.D. from the California Institute of Technology working with Robert H. Grubbs, and performed postdoctoral studies at the Massachusetts Institute of Technology under Mark S. Wrighton. He began as an Assistant Professor at the University of Pennsylvania in 1990 and returned to MIT in 1996 as a Full Professor.
Swager is best known for advancing new chemical sensing concepts based on molecular electronic principles. He introduced the concepts of charge and energy transport through molecular and nanowires as a method to create amplified signals to chemical events. These methods gave rise to the sensitive explosive sensors that have been commercialized under the trade name Fido. He demonstrated the integration of molecular recognition into chemiresistive sensors, first with conducting polymers and later with carbon nanotubes, and these methods were commercialized by C2Sense.
Conor Walsh
HARVARD
Paul A. Maeder Professor of Engineering and Applied Sciences at the John A. Paulson Harvard School of Engineering and Applied Sciences and Associate Faculty Member at the Wyss Institute for Biologically Inspired Engineering
Conor Walsh is the Paul A. Maeder Professor of Engineering and Applied Sciences at the John A. Paulson Harvard School of Engineering and Applied Sciences and an Associate Faculty Member at the Wyss Institute for Biologically Inspired Engineering. He is the founder of the Harvard Biodesign Lab, which brings together researchers from the engineering, industrial design, apparel, clinical, and business communities to develop new disruptive robotic technologies for augmenting and restoring human performance. This research includes new approaches to the design, manufacture, and control of wearable robotic devices and characterizing their performance through biomechanical and physiological studies so as to further the scientific understanding of how humans interact with such machines. Example application areas include enhancing the mobility of healthy individuals, restoring the mobility of patients with gait deficits, assisting those with upper extremity weakness to perform activities of daily living, and preventing injuries of workers performing physically strenuous tasks. His multidisciplinary research spans engineering, biology, and medicine and has led to multiple high impact scientific papers as well as technology translation. Multiple technologies from the lab have been licensed to industry. He is a co-founder of Verve, Inc. commercialization of a back assist exosuit and the ReStore soft exosuit from ReWalk Robotics is now FDA and CE mark approved for use during gait rehabilitation poststroke. He is the winner of multiple awards including the Presidential Early Career Award for Scientists and Engineers and the MIT Technology Review Innovator Under 35 Award.
Dennis G. Whyte
MIT
Former Department Head of Nuclear Science and Engineering, Former Director, MIT Plasma Science and Fusion Center &
Hitachi America Professor of Engineering
Sophie Vandebroek
Strategic Vision Ventures
Founder and Owner of Strategic Vision Ventures, Member of MIT’s Dean of Engineering Advisory Council, Former IBM and Xerox executive
Dennis Whyte’s research in the magnetic confinement of plasmas sets us on an innovative and faster path to producing fusion energy. He is one of the leaders of the SPARC project, a collaboration between Commonwealth Fusion Systems and MIT, to design and build a high‐field fusion device to demonstrate net energy production for the first time. Many of the technology approaches underpinning the high‐field approach to fusion energy, including SPARC, were formed over the last decade in his MIT fusion design class: utilizing magnets from high‐temperature superconductors, demountable magnets for modular assembly and maintenance, and liquid immersion blankets for robust energy removal. He is a fellow of the American Physical Society, has served on panels for the National Academies and Royal Society, and has won the Fusion Power Associates Leadership Award and the 2013 Nuclear Fusion Prize. He previously served as Department Head of Nuclear Science and Engineering at MIT. His is a co‐founder of Commonwealth Fusion Systems, whose goal is the rapid commercialization of fusion energy to tackle climate change. Whyte earned his BS and PhD in Canada.
Sophie Vandebroek is founder and owner of Strategic Vision Ventures LLC, a strategic advisory firm working with clients worldwide. Most recently, Sophie served as the Chief Operating Officer of IBM Research where she was instrumental in creating the MIT-IBM Watson AI Lab. Previously, Sophie was Xerox’s Chief Technology Officer and led Xerox’s global laboratories, including PARC, Inc., an innovation services company for over a decade.
In 2019, Sophie became the Inaugural School of Engineering Visiting Scholar at MIT. She has been a member of the Advisory Council of the Dean of Engineering at MIT for the past decade. She is also a trustee at the Boston Museum of Sciences and a member of the International Advisory Board of the Flanders AI Research Program. Sophie is a member of the Board of Directors of IDEXX Laboratories, the global leader in veterinary diagnostics, and on the Supervisory Board of Wolters Kluwer, a global provider of professional information, software solutions, and services.
Sophie is a Fellow of the Institute of Electrical & Electronics Engineers, an inductee into the Women in Technology International Hall of Fame and elected member of the Royal Flemish Academy for Arts & Sciences. Sophie’s passion for creating inclusive organizations where innovation thrives has earned her many awards among which is Xerox’s Inaugural Lifetime Diversity Leadership Award of Distinction.
Sophie grew up in Belgium and earned a master’s degree in Engineering Magna from KU Leuven, Belgium and a Ph.D. in Engineering from Cornell University, Ithaca, New York.
Business Advisory Board
Industry veterans to guide our portfolio companies to financial success and global reach.
Sébastien Bazin
Accor
Chairman & CEO
Chair of Strategic Partnerships, Safar Partners
Anurag Bajpayee
Gradiant Corporation
Co-Founder & CEO
Mark Chaney
Calvary Robotics
Co-Founder & CEO
Robert P. Cochran
Build America Mutual
Managing Director & Chariman of the Board
He joined Accor’s Board of Directors in 2005 and, via Colony Capital, became a Paris Saint-Germain shareholder in 2006 and the club’s Chairman in 2009.
In August 2013, he resigned from his duties at Colony Capital and was appointed Chairman and CEO of Accor.
Sébastien has been Chairman of the Théâtre du Châtelet’s Board of Directors since 2015 (and a Board member since 2013), is Vice-Chairman of the Gustave Roussy Foundation’s Supervisory Board, and has been a member of GE’s Board of Directors since 2016.
Prior to founding Gradiant, Anurag received his PhD in mechanical engineering from the Massachusetts Institute of Technology.
Mark Chaney is passionate about holding strong values and uniting leadership positions within the company to follow through with the vision of Calvary through its employees and customers that they serve. Under Mark Chaney’s leadership, Calvary Industries has grown and expanded during periods of economic and industrial challenges and has been able to forge business relationships internationally to expand their market. The company has nearly doubled in the past year and a half, and grown to almost 300 employees.
Mark’s commitment to innovation has spawned a new Innovation lab which has developed new products such as Opti-Cool (Energy efficient Data Center Cooling Equipment) and X-Cell (Modular and Redeployable Assembly Equipment). Bringing high technology to manufacturing automation, machine tooling and robotics is important to the future of Calvary.
Mark bases a high level of importance on the values of reliability, integrity, high quality, honesty and respect for all employees and customers, as well as takes a strong personal interest in helping set strategies for continued growth and success for Calvary’s Market with executive leaders in the company.
He graduated from Centre College (BA,’71) and Duke University School of Law (JD), followed by a federal judicial clerkship for Judge Pierce Lively (6th Circuit Court of Appeals).
Shreya Dave
via separations
Co-Founder & CEO
Nicolas Fourt
ACOFI GESTION
Deputy CEO
Seth W. Lawry
Thomas h. lee partners
Advisory Partner
Priti Agarwal Marteil
PCINVEST
CIO
She also holds bachelor’s and master’s degrees from MIT in mechanical engineering and technology & policy.
For four years prior to the formation of Wellspring, he was in charge of acquisitions at EXOR America Inc., the U.S. investment arm of the Agnelli Group. For two years before joining EXOR, Greg was vice president and co-founder of Clegg Industries, Inc., an investment firm backed by Drexel Burnham Lambert Incorporated to invest in leveraged acquisitions of middle market manufacturing companies. From 1983 to 1988, Greg was a mergers and acquisitions lawyer at Paul, Weiss, Rifkind, Wharton & Garrison in New York.
Greg has served on the boards of more than twenty public and private companies. In addition to his for-profit board activities, Greg also serves as President of the Board of The Kitchen and Co-Head of the Director’s Council at The Whitney Museum of American Art. Greg received a Bachelor of Arts degree from Hampshire College and a JD from the Benjamin N. Cardozo School of Law, where he was Editor-in-Chief of the Law Review. Greg and his wife have three children and live in New York City. Greg Feldman is a member of the Investment Committee and non-employee of Safar Partners.
Nicolas oversaw the acquisition from Temasek of Singapore of structured finance activity Nexgen in 2005. He co-managed the Lazard-Natixis joint venture from 2006 onwards. As CEO of advisory boutique Alfafinance between 2009 and 2014, he was more specifically involved in debt restructuring and advisory of major clients in banking and insurance sectors. He merged Alfafinance with asset management company Acofi in 2014 to set up an innovative direct lending platform managing $2 billion in real estate, energy, SME, and early stage innovation actors in Europe.
Nicolas is a graduate from French National Statistics School, holder of a Masters in Economics from Université de Paris Sorbonne, and a chartered actuary.
Seth’s twenty years of corporate board service spans both public and private companies. He has also served as a trustee of Colby College for twelve years and is active in other private and non-profit institutions.
Seth holds a B.A. in Economics and German Studies from Williams College and an M.B.A. from the Stanford Graduate School of Business.
Priti Agarwal Marteil is currently acting as CIO for PCINVEST, a French family office investing after having had a long career in finance – M&A, investing and consulting globally (India, USA, Israel, France). Having worked in India in investment banking in the early 90, she moved to the US in 1997 where she worked in Telecom Consulting for the likes of At&T and Motorola before transitioning to investing where her investments included the Al Bawaba Group, the leading Middle-East news portal. Once she moved to France, she worked at Natixis Private Equity as Partner in charge of Business Development and M&A. Since 2011 she has advised family-owned companies such as ID Kids (leading textile retailer), Basaltes (largest independent French granulate producer), Titan (Greek cement manufacturer), Sofisport (world leader in leisure shooting and self-defence products) etc, in their investments and cross-border M&A activities.
Priti has a Diploma in Software and a Bachelors in Commerce (Accounting and Law) from India and is a graduate of HEC (Ecole des Hautes Etudes Commerciales) in France.
Chris O'Donnell
OAM Quant
Founder and CEO
Bijan Salehizadeh
NaviMed Capital
Co-Founder & Managing Director
Mark Zupan
Alfred university
President
Chris O’Donnell is the Founder and Chief Executive Officer of OAM Quant, an investment management company whose aim is to consistently generate alpha in liquid global markets using a disciplined approach rooted in data science, technology, and finance.
Chris has in excess of 25 years of investment and entrepreneurial experience. Investments have spanned all business stages (from seed to mature) across numerous industry sectors. Chris is a serial entrepreneur having founded, built, and led multiple companies.
He holds a B.S. in Finance and Accounting from Ithaca College and an MBA from the William E. Simon Graduate School of Business Administration at the University of Rochester. Chris is a Board Member of the Wegman Family Foundation and serves on the Safar Partners Advisory Board.
Bijan Salehizadeh has 20 years of healthcare operating and investment experience. At NaviMed, he sits on the firm’s Investment Committee and is responsible for leading investments and overseeing portfolio companies with a particular focus on healthcare providers and pharmaceutical services. Prior to co-founding NaviMed Capital, he was a General Partner at Highland Capital Partners, where he focused on growth stage healthcare investments.
Prior to joining Highland Capital Partners in 2004, Dr. Salehizadeh spent several years in a variety of healthcare operational roles at publicly traded and emerging growth companies.
Dr. Salehizadeh led NaviMed’s investments in and currently serves on the Board of Directors of CenterPointe Behavioral Health System, The CM Group, Scientific Commercialization, and Velocity Clinical Research. He also serves on the Board of Directors of OPN Healthcare. Dr. Salehizadeh previously served on the Board of Directors of several companies including Auris Health (sold to Johnson & Johnson for $5.7 billion), BARRX Medical (sold to Covidien for $400 million), Hyperion Therapeutics (IPO; sold to Horizon plc for $1.1 billion), Lumere (sold to GHX), and Opgen (IPO). In addition, he has sourced or been actively involved in Highland Capital Partners’ investments in AVEO (IPO), Baronova, Conor Medsystems (IPO; sold to Johnson & Johnson for $1.4 billion), kyruus, and Pharmaca Integrative Pharmacy.
Dr. Salehizadeh holds an AB in Molecular Biology from Princeton University, an MD and Master’s in Science in Health Policy from Columbia University, and an MBA from Harvard Business School. He is also a graduate of the Kauffman Fellows Program.
Prior to that, he was Dean of the University of Rochester’s Simon Business School for ten years, after which he served for two years as the John M. Olin Distinguished Professor of Economics and Public Policy and Director of the Bradley Policy Research Center at the Simon School. He had previously served as the Dean of the University of Arizona’s Eller College of Management for seven years. While Dean at the Simon Business School, he championed an $85 million fundraising campaign that added 9 new endowed professorships, quadrupled philanthropic support for scholarships, and more than doubled annual discretionary giving; the campaign ultimately raised more than $96 million. He also established an undergraduate business program in partnership with the College of Liberal Arts & Sciences; pioneered specialized masters programs in finance, marketing, accounting, business analytics, and medical management; and doubled overall graduate student enrollment at Simon.
Holds a Bachelors degree from Harvard University, and his PhD from Massachusetts Institute of Technology.
Our Portfolio
5x5 Technologies
Remote monitoring of physical assets
24/7 Solar
MIT
Round-the-clock clean electricity
2Pi Optics
MIT
Flat Optical Metasurfaces
AcousticaBio
Harvard
Advanced Manufacturing for Life
5×5 TECHNOLOGIES develops software to reinvent inspection of physical equipment in the field. Their software solutions convert visual information like photographs and videos taken by drones into interactive 3D models. This tool allows their customers to analyze and maintain equipment like cell phone towers in the field, replacing dangerous and costly manual inspections.
247Solar Inc. (“247Solar” or the “Company”), an MIT spin-out, leverages its proprietary clean energy technology to engineer turnkey energy solutions for its industrial customers, utilities, and developers of data centers, green hydrogen, and desalination. It then finances/owns, builds, and operates them through SPVs to sell clean electricity and process heat 24 hours a day, reducing customers’ costs and carbon emissions.
2Pi Optics is developing single-element, flat fisheye metalenses with extremely wide field-of-view (nearly 180 degrees). A metalens is a lens that uses carefully calibrated nanostructures to focus and alter the properties of light. 2Pi’s advanced metalenses offer unparalleled resolution and field of view, which will allow them to directly compete with traditional, expensive, multi-element curved fisheye lenses. 2Pi’s metalenses will be particularly useful for the next generation of 3D sensing technologies.
AcousticaBio is an advanced manufacturing company solving the greatest challenges in drug delivery for novel therapeutics. Today, millions of patients face the burden of frequent hospital visits, enduring painful, costly, and time-consuming intravenous (IV) injections to receive their life-saving medications. AcousticaBio transforms this process, making drug delivery as simple as receiving a routine flu shot. Utilizing advanced microparticle technology and our Harvard-patented acoustophoretic platform, we convert intravenously delivered biologic products into highly concentrated, small-volume subcutaneous injections – all without the use of solvents or cumbersome post-processing.
Active Surfaces
MIT
Thin-film solar technology
Agility Robotics
Bipedal robots
Altaeros
MIT
Tethered Aerostats
Ancilia Bio
Virome database focused on creating probiotics and biotherapeutics
Active Surfaces is commercializing an ultra thin-film solar technology based on decades of MIT research. Its technology provides thin-film solar panels for commercial warehousing applications, which can unlock terawatts of dual land use next generation deployment. Active Surfaces’ innovative manufacturing approach drives down manufacturing costs, is transformational for semiconductor and electronics manufacturing, and provides thin-film solar panels for commercial warehousing applications.
AGILITY ROBOTICS manufactures highly capable legged robots. Their latest model, Digit, can walk, navigate, and carry boxes to perform simple tasks with minimal or no additional programming. Agility is exploring use cases in diverse markets such as last-mile logistics, telepresence, automated inspection, entertainment, and academic research
Altaeros is developing tethered, aerial cell towers designed to extend communication networks to areas in need. Altaeros’ SuperTowers float over ~1000 feet off the ground and can carry a variety of payloads including 4G, 5G, IoT, fixed wireless, environmental monitoring, and others. Each SuperTower can replace numerous ground-based towers, offering a quicker and less expensive way to build communications infrastructure or roll out new technologies.
Ancilia is an early-stage life sciences company out of NCSU working on a platform technology comprised of CRISPR-edited bacteria to boost performance and viability of live biotherapeutics and microbial products. Ancilia is creating a virome database, understanding the relationship between virus and bacteria, and producing CRISPR-enabled immunized bacterial products that have enhanced survival against relevant viromes and therefore enhanced efficiency.
Aramis Biosciences
Harvard
Therapeutics for dry eye disease
Axoft
Harvard
Soft and Scalable Neural Probe Technology
C2 Sense
MIT
Advanced sensing solutions for a healthier and safer world
Chromatic 3D Materials
Next-generation 3D printing materials
ARAMIS BIOSCIENCES is committed to the development of therapeutics in the area of ocular inflammation and pain. In order to address this domain, Aramis is producing therapeutics to address dry eye disease (DED).
Axoft makes soft and scalable neural probes for brain implants. By leveraging its proprietary soft material, Axoft probes can record neuron signals in the brain with long-term signal stability, high-bandwidth recording, and greater safety than existing solutions. Axoft’s first product will be a brain implant to create brain-machine interfacing for paralyzed people to control neuroprosthetics
Chromatic 3D Materials (C3DM) is inventing the next generation of 3D printing materials with the durability to meet the requirements for finished manufactured goods. Chromatic 3D Materials is developing the technology to print with thermosets, a broad class of materials including polyurethanes, silicones and epoxies. The adaptability, durability and resilience of these materials are unmatched by the thermoplastics used in conventional 3D printing processes.
Circe Biosciences
Carbon-negative food
Clerio Vision
University of Rochester
Vision correction enabled by laser technology
Cogito
MIT
Real-Time Voice AI to Augment Emotional Intelligence
Commonwealth Fusion Systems
MIT
Commercial fusion energy systems for clean power generation
COGITO is an AI company that augments emotional intelligence and helps elevate human performance. Their real-time, streaming voice AI instantly analyzes hundreds of conversational behaviors and emotions to provide live in-call guidance to contact center agents and real-time measurement of customer experience.
Concerto Biosciences
MIT
Microbial therapeutics
Cypris
Structural Color Coatings
DMAT
MIT
Concrete production company
Droplet Biosciences
Cancer Diagnostic Company
Microbiomes—complex, bustling ecosystems of bacteria, fungi, and viruses—influence the health of every person, plant, animal, and environment. When a microbial ecosystem loses one of its key functions, it can contribute to the onset or progression of recurrent infection, chronic inflammation, and other disease states. Using a novel screening tool called kChip, Concerto Biosciences creates microbial Ensembles, combinations of microbes that restore beneficial functions to a microbiome, healing people, plants, and the planet. Concerto’s first products will treat skin disorders like eczema, allowing hundreds of millions of people globally to enjoy a life free from inflamed, itchy skin.
By assembling two commonly available polymers into molecules that reflect different wavelengths of light, Cypris Materials can produce structural color coatings. Cypris’ coatings are cheaper and easier to formulate than competing structural color options, and eliminate the need for toxic chemicals and heavy metals commonly used in the colorants industry.
Droplet designed an oncologic diagnostic test to assess patients’ chance of cancer recurrence at a higher rate than comparable tests – by analyzing surgical drain fluid collected directly after surgery. Comparable tests are completed multiple times on a follow up basis and commonly give a short notice of recurrence. Droplet’s test is completed directly after surgery which provides physicians and patients an earlier notice of recurrence, enabling earlier treatment following surgery and improving patient outcomes.
EagleDream Technologies
Cloud transformation and software solutions
Embr Labs
MIT
Wristwear device to change customers’ perception of temperature
Encora
MIT
Noninvasive Tremor Treatment
EVOLOH
Green hydrogen at scale
Encora Therapeutics is medical device company focused on treating tremors. Encora’s first product is a wearable wrist device that uses vibratory neurostimulation to reduce the magnitude of hand tremors. With this device, Encora is initially targeting patients with Essential Tremor (ET) and Parkinson’s Disease (PD). Encora’s device offers instant tremor relief and can enable patients to resume activity previously hindered by hand tremors, like writing, eating, drinking, and working.
EVOLOH Inc., a green hydrogen technology company, is at the forefront of the development and commercialization of low-cost and mass-produced water electrolyzers. The company’s patented electrolyzers incorporate a design for high-speed, low-cost manufacturing and secure supply chains, making green hydrogen production possible at gigawatt scale anywhere in the world.
Finwave
MIT
Semiconductor Chips
Fluorityx
PFAS detection
MIT
Formic
Robotics and robotics financing
Foundation Alloy
Advanced materials technology
Finwave Semiconductor, formerly Cambridge Electronics, Inc (CEI), is an MIT-founded startup that is pioneering advances in 3D GaN semiconductor chips for use in 5G communications. Finwave’s GaN FinFET (gallium-nitride fin field-effect transistor) has significant advantages over existing mainstream chip technologies for certain applications, including for 5G radios
Fluorityx is making affordable, simple detectors for on-site analysis and confirmation of the presence/absence of regulated perfluoroalkyl and polyfluoroalkyl substances (PFAS). Fluorityx’s first generation PFAS polymer sensor is adopted from a commercially successful explosive detection system modified to be specific for PFAS and will detect PFAS down to parts per trillion concentration within an hour.
Formic is a late-stage, revenue-generating robotics and robotics-financing company. Formic has developed a series of robots with 5 primary use cases and rents these robots out to customers for use in their factories and other facilities. Formic receives revenue from renting out the robots, from the use of its software for robot monitoring and operation, and from continued robot maintenance.
GelMEDIX
Harvard
Biomaterials for improved drug delivery
Gradiant Corp.
MIT
Water treatment and recycling systems for more sustainable business practices.
Gradient Comfort
Efficient heating and air conditioning
Harmony
MIT
Using fermentation for better baby formula
GELMEDIX develops solutions for drug delivery. GelMEDIX can replace today’s drug regimens that require application of eye drops 4-12x per day over several weeks with a single, non-invasive gel patch. GelMEDIX’s gel could also be used as a drug-eluting sealant for other wet mucosal surfaces, like the ear or mouth, and could be adapted for post operative work, including as a heart or lung sealant
Gradient Comfort’s mission is to cool the world by transforming every home to be more comfortable and healthy for the people who inhabit it — without compromising the environment. Gradient has developed polymer-based heat exchangers that allow for cheaper production and higher cooling efficiency, and the first product to utilize this is a high-efficiency and low-emission heat pump-based heating and cooling system.
Harmony Baby Nutrition is developing allergen-free, affordable baby formulas to address the problem of baby allergies to cow’s milk, using precision fermentation. Harmony’s formula bears a 64% resemblance to human breast milk, a very high percentage in relation to competitors. Harmony is able to vary the ratio of whey to casein protein in their product, which enables them to produce different baby food formulations for different stages of development.
Health Care Originals
University of Rochester
Remote respiratory monitoring device for better healthcare
Honeoye Remedies
University of Rochester
Scientific advancements for natural skin care
Humanyze
MIT
Data analytics and AI to make companies more productive
Imago Rehab
Harvard
Digital health solution for physical rehab
HUMANYZE is an AI company that uses data analytics to measure and improve the organizational health of companies, making them more efficient and productive. Through their use of sensors and AI technology, Humanyze analyzes existing corporate data to drive actionable organizational health scores that help companies make objective and informed decisions.
Imago Rehab enables superior hand recovery outcomes for stroke survivors through a combination of home-use wearable robotics and digital health. Their first product is a soft robotic glove that allows stroke survivors to complete high-intensity rehab from the comforts of home along with personalized coaching through telehealth sessions with occupational therapists.
InchFab
MIT
Turn Key MEMS Microfabrication Solution
ISEE
MIT
Autonomous vehicles for logistics centers
Kebotix
Harvard
AI-enabled automated materials discovery
Lasso
Harvard
Creating the right taste and texture in healthier foods
ISEE is an early-stage MIT spinout that is developing technologies to support autonomous vehicles. ISEE is not focused on developing vehicles to drive autonomously on public roads; instead, ISEE is developing autonomous trucks that are used to move containers and goods within low-speed, privately-held logistics centers, such as container yards.
Lightsynq
Harvard
Universal optical quantum interconnects for commercial use
Liquid AI
MIT
AI applications for the creative mind
Membrion
Ceramic Membranes for Harsh Water Treatment
MetOx Technologies
High temperature superconducting tape
Membrion is an early-stage startup that is developing ceramic ion-exchange membranes for water desalination and treatment. Unlike existing membrane technologies, Membrion’s CeramIX membranes can survive in harsh industrial wastewater for long periods of time (1-2 years), reducing maintenance and replacement costs compared to competitors.
MetOx Technologies manufactures next generation high temperature superconducting tape. These tapes enable innovations in electrical applications: high-field magnets for fusion power and next generation MRI’s; advanced motors and cables; space-based electrical storage; and a myriad of new applications in clean and renewable energy.
Nanoramic Laboratories
Nanomaterial ultracapacitors and batteries
Nelumbo
UC Berkeley
Additive technology for advanced industrial applications
Omnipulse
MIT
Multiple dose therapeutic delivery in a single injection
Pirouette
MIT & Harvard
They make injections easy!
NELUMBO is an advanced materials company developing high-performance surface modifications for industrial surfaces (metal, glass and fabric). First applications are in refrigeration and HVAC for residential and commercial heat pumps where Nelumbo has first customers.
Omnipulse is an early stage drug delivery platform, working on multiple dose of drug delivery of vaccines and other therapeutics with a controlled release in a single injections. Omnipulse’s technology consists of microparticles made of an FDA approved material (shell) that is filled with an active pharmaceutical ingredient (API)(core) in a core-shell form factor.
At Pirouette, we believe that innovation drives progress. Our dedicated team of engineers and scientists are developing the latest technologies to offer cutting-edge treatments that enhance patient care and improve lives. From groundbreaking therapies to advanced drug delivery systems, every innovation reflects our commitment to excellence and our passion for transforming healthcare. Together, we’re crafting a healthier tomorrow with every step we take. Join us on this journey of discovery and advancement.
Quadratic 3D
Zero-touch industrial-scale fabrication of complex geometries
Quaise
MIT
Millimeter wave drilling systems
QuEra Computing
Harvard
Quantum computing hardware
Radical Plastics
Biodegradable plastics
QUAISE is developing and commercializing novel millimeter wave drilling systems to harness geothermal energy around the globe, overcoming the geographic constraints limiting this energy source today. Quaise’s technology enables the clean energy transition by accessing the largest source of power-dense clean energy on Earth.
QuEra Computing, Inc. is an early-stage quantum computing startup founded primarily out of Professor Mikhail Lukin’s laboratory at Harvard, with co-founders from both Harvard and MIT. QuEra is developing quantum computing hardware using neutral atoms, which is relatively unique compared to other major quantum computing initiatives and companies.
RADICAL PLASTICS has developed a patented catalyst that renders conventional plastics biodegradable in the natural environment. Items made from the Radical Plastics compound perform just like regular plastics. But if they end up in the environment, the free radical catalyst converts the plastic into a material that microbes recognize as food.
Righthand Robotics
Harvard
Autonomous piece-picking robotic solutions
Satelles
Secure Satellte Navigation Data
Seaspire Skincare
Harvard
Science-based Skincare
SightStream Biotherapeutics
Harvard
Vision restoration treatments
RIGHTHAND ROBOTICS creates robots that can grasp products of different sizes, shapes, and weights. The combination of suction cups and compliant finger-like grippers handles a wide range of objects efficiently, and their cameras and machine-learning capacities allow the robots to learn from past mistakes.
Satelles has developed a low earth orbit (LEO) satellite system which provides accurate position, navigation, and timing data (PNT), indoor penetration, and added security to prevent malicious attacks. This is a global, private sector solution to unsecure and obsolete GPS and unscalable ground systems for PNT data. Satelles’ satellite time and location (STL) method provides a trusted PNT solution that is highly resistant to cyberattacks and other signal manipulation methods.
Seaspire is a life sciences company creating high performance skincare ingredients inspired by marine biodiversity. The Seaspire team is pioneering a new category of multifunctional skincare materials that are more effective, safer, and more environmentally conscious. Seaspire’s first product uses xanthrochrome, an organic natural product found in arthropods and cephalopods, which can be formulated to not only protect the skin from UV-induced damage, but also restore through innovative delivery.
SightStream Biotherapeutics is an early-stage startup affiliated with Harvard University. SightStream develops cytoprotectives to prevent and reverse the cell death to aid patients in recovering from ocular cell damage. SightStream is accomplishing this through use of an α-MSH analogue, which has potential for use as a stand-alone therapeutic for corneal endothelial cell dystrophies, persistent corneal epithelial defects, and retinal diseases, and as an additive to ocular stem cells to enhance cell stability, durability, and integration in diseased tissues.
Soufflé Therapeutics
MIT
Targeted Gene Therapy
SwiftSolar
MIT
Lightweight, flexible solar cells
Syntis Bio
MIT
Synthetic tissue coatings
Turing
MIT
Turing
Soufflé is developing a platform for targeted, tissue-specific genetic therapy delivery through the discovery of new cell proteins and pathways that can precisely deliver genetic payloads. Its first therapies can target skeletal muscle and cardiomyocyte cells for treatment of muscular dystrophies and heart diseases.
The Turing Company is an AI and IoT company that provides software and IoT devices to optimize, increase efficiency, and automate water assets as well as operations like landscaping. Turing’s first products are Turing Optimal Performance (TOP) platforms, which deliver end-to-end digital solutions that drive cost savings and sustainability in industrial water and water distribution networks and in the landscaping industry, respectively.
Ubiquitous Energy
MIT
Transparent solar panels
Venti Technologies
MIT
Autonomous Logistics Solutions
Veo Robotics
MIT
Systems for human-machine collaboration
Verve Motion
Harvard
Flexible exosuits for industrial applications
Venti Technologies, Inc. is an MIT spinout focused on developing autonomous logistics solutions. Instead of developing autonomous vehicle technologies for public roads, such as consumer vehicles and long-distance trucking, Venti is developing software to pilot autonomous vehicles in private logistics centers, such as shipyards and factories
Veo Robotics uses sensing and 3D vision technology to allow humans and robots to collaborate safely and efficiently in manufacturing and logistics settings. Veo’s safety certified FreeMove solution uses proprietary algorithms, sensing, and control systems to allow robots to sense humans and their locations, so that they can safely work around humans without danger of injury or need for a robot cage
Verve Motion is the developer of SafeLift. The technology behind SafeLift has been developed at Harvard over the past decade, and is based on the latest advances in robotics, apparel design, and movement science. The suit applies assistance in parallel with the user’s muscles and responds to their movement in milliseconds. It combines state-of-the-art motion tracking technology with powerful robotic actuators and integrates it all into a lightweight and easily wearable device that doesn’t restrict normal activities.
The result is a device that takes 30% of strain off of people when they perform physically strenuous tasks, supporting the back and hips to reduce risk of injury, improve lifting form and posture, and greatly lower fatigue and soreness. Even better, it is incredibly simple to integrate our system into your workplace: it takes less than 30 seconds to put on, one size fits most, and the suit is ready to wear right out of the box.
Via Separations
MIT
Membrane based filtration
Viken
Public safety technology solutions
Xibus
MIT
Rapid bacteria detection for improving food safety
Zanskar
Big data meets geothermal exploration
Viken Detection is a late-stage, revenue-producing startup that focuses on public safety technology. Viken manufacturers and sells a variety of products in this area, including handheld X-Ray imaging tools and lead-paint detectors, walk-through and whole-vehicle X-Ray scanners, and chemical detectors.
VIA SEPARATIONS is a membrane company applying novel filtration to reduce the energy used in industrial separation processes by 90%. With applications across food and beverage, pulp and paper, pharmaceuticals, and chemical production, Via is targeting the 10% of global energy consumption that is wasted in thermal separation processes.
Recent news
QuEra claims quantum error correction breakthrough with 2-to-1 qubit ratio
Quantum computers are prone to high error rates, so, to make qubits usable, a lot of redundancy is required. It typically takes hundreds—even thousands—of physical qubits to make one usable, “logical” qubit. This has been a major obstacle to the development of...
Axoft Secures $55M Series A to Advance Clinical Trials Globally for its Bio-Inspired, Implantable Brain-Computer Interface
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Axoft, a neurotechnology company, today announced it has raised an oversubscribed $55 million Series A led by C.P. Group Innovation. Alumni Ventures, the Stanford President’s Venture Fund, Hillhouse Investment and Gaorong Ventures...
Clerio Vision to Present World’s First LCA-Correcting Soft Contact Lens at ARVO 2026 Annual Meeting
ROCHESTER, N.Y., April 29, 2026 /PRNewswire-PRWeb/ -- Clerio Vision, Inc., a developer of next-generation laser-based vision correction platforms, announced that its research team will present data at the 2026 Association for Research in Vision and Ophthalmology...
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