HIV remains a public health issue. Approximately 39 million individuals around the world have HIV. However, not all individuals who know their HIV status are accessing treatment; 93% of the individuals who are accessing treatment were virally suppressed.
Since the introduction of the first antiretroviral therapy (ART), zidovudine, for HIV in 1987, significant advances in the efficacy and safety profiles of ART have occurred. Introduction of a three-drug ART regimen in 1996 largely overcame prior limitations of single- and two-drug regimens that might be subject to eventual resistance. Three-drug regimens have become the standard of care for people living with HIV. This has resulted in transitioning infection with HIV to a manageable chronic disease for those who achieve durable virologic suppression. Clinical evidence increasingly demonstrates that those who achieve and maintain undetectable viral load by taking ART are less likely to sexually transmit the virus. For example, studies have shown that early initiation of ART in serodiscordant heterosexual couples limits HIV-1 transmission.
How much do you know about ART in individuals who are ART-naive? Test your knowledge with this quick quiz.
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Cite this: Michael Stuart Bronze. Fast Five Quiz: Antiretroviral Therapy for HIV Infection for ART-Naive Individuals - Medscape - Feb 26, 2024.
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