We can make the pc talk on window with a code like the one below, using the win32com module.
import sys
from win32com.client import constants
import win32com.client
speaker = win32com.client.Dispatch("SAPI.SpVoice")
print ("Type word or phrase, then enter.")
print ("Ctrl+Z then enter to exit.")
while 1:
try:
s = input()
speaker.Speak(s)
except:
sys.exit()