Predictive Science Academic Alliance Program

The Predictive Science Academic Alliance Program (PSAAP) is the primary mechanism by which the NNSA’s ASC program engages the U.S. academic community in advancing science-based modeling and simulation.  In 2025, nine PSAAP IV centers were established with a primary focus on the following areas:

• Discipline-focused research to further predictive science and enabled by effective exascale computing and data science technologies;
• Mathematics and computer science (CS) technologies and methodologies to support effective exascale computing in the context of science/engineering applications (development and demonstration);
• State-of-the-art machine learning (ML) and data science technologies for predictive science and engineering (utilization and advancement);
• Predictive science based on verification, validation, and uncertainty quantification (VVUQ) for large-scale simulations; and
• Workforce development of the next-generation computational scientists.

Predictive Simulation Centers (PSCs) focus on scalable application simulations, targeting large-scale, integrated multidisciplinary problems.  PSCs develop and demonstrate computer science technologies and methodologies that will advance Exascale computing, and demonstrate integrated, verified, validated predictive simulation with uncertainty quantification.

Focused Investigatory Centers (FICs) are tightly focused on a specific research topic in either a science/engineering discipline, or an Exascale enabling technology, of interest to NNSA’s mission.
 

Predictive Simulation Centers

	University of Florida Center for Multiscale Modeling of Multiphase Combustion
	Massachusetts Institute of Technology Center for the Exascale Simulation of Coupled High Enthalpy Fluid-Solid Interactions
	University of Michigan Center for AI-enabled Exascale Prediction of Long-time Events in Multimaterial Shock-assisted Chemical Reactions
	Oregon State University Center for Advancing the Radiation Resilience of Electronics (CARRE)
	University of Virginia Center for Stochastic Simulations of Ablative Geometries with Error-Learning in Space and Time

Focused Investigatory Centers 

	Brown University Center for Information Geometric Mechanics and Optimization (CIGMO)
	University of California at San Diego Center for Simulation and design of Heterogeneous Architectures for Performance and Energy absorption (SHAPE)
	Michigan State University High Order Plasma Turbulence Modeling for Z-Pinch
	University of New Mexico Center for Optimized Modern Parallel Adaptive System Software (COMPASS)