PCORnet is a national resource, funded by PCORI®, that enables insights from high-quality health data, patient partnership, and research expertise to deliver fast, trustworthy answers that advance health outcomes.
Mark your Calendar! PCORI to Announce New Funding Opportunities for PCORnet® Studies
On April 1, PCORI will release the Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) to support high-quality patient-centered comparative clinical effectiveness research (CER). Category 3 supports PCORnet® Studies with direct costs of up to $12 million.
PCORnet® Playbook
Researchers who partner with PCORnet® have access to unique representative health data, research expertise, and patient insights. Whether you are a new or an experienced researcher, the PCORnet® Playbook is your go-to guide for navigating the PCORnet infrastructure, tapping into expert support, and integrating patient perspectives into your research from the start.
Research Highlights Illustrate Power of PCORnet®
Learn how researchers are using PCORnet to improve patient outcomes by fueling the kind of large-scale research needed to:
- Understand how different metabolic pathways interact
- Answer key questions in cardiovascular research
- Solve challenges in nephrology research
- Explore approaches to pediatric research
OneFlorida+
OneFlorida+, a PCORnet® Clinical Research Network, was created by aligning partners, including patients, clinicians, health systems, researchers, payers of third-party claims, and state agencies in Florida, to provide an enduring infrastructure for interventional and observational studies within all of Florida’s 67 counties. OneFlorida+ has since expanded to parts of Alabama, Georgia, Arkansas, California and Minnesota.
Check out the OneFlorida+ HERO Communications Toolkit, compiled to increase awareness about the PCORnet® HERO Research Program and increase enrollment in the HERO Registry..
Special Journal Supplement
A February 2026 PCORI-sponsored supplement of the journal Medical Care looks at the scope and scale of PCORnet. The 19 peer-reviewed open-access articles demonstrate the robust scientific value of PCORnet in accelerating patient-centered comparative clinical effectiveness research.
Event
Wednesday, April 22
12-1 pm (ET)
Join us for the webinar, Empowering Multi-Site Studies via Federated Learning Using Privacy-Preserving Distributed Algorithms (PDA).
Tools to Speed Study Start-up
Conduct patient-centered comparative clinical effectiveness research more efficiently by addressing some of the most time-consuming, costly, and difficult aspects of study start-up.