Founder of Equ Healthcare with MIT research experience
Connects Equ Healthcare product work with MIT research in explainable AI, digital health, neurosymbolic methods, and scientific discovery.
Building interpretable AI for health and scientific discovery.
Connects Equ Healthcare product work with MIT research in explainable AI, digital health, neurosymbolic methods, and scientific discovery.
Current focus
Dr. Omar Costilla Reyes works across artificial intelligence, neuroscience, medical engineering, digital health, and scientific discovery. His focus is building systems that are technically rigorous, understandable, useful, and grounded in evidence.
His research background across MIT Brain and Cognitive Sciences, the Institute for Medical Engineering and Sciences, and the Computer Science and Artificial Intelligence Laboratory connects brain research, translational medicine, and computer science. That foundation informs his work on interpretable AI, neurosymbolic programming, digital phenotyping, and multimodal health data.
Through Equ Healthcare, this trajectory moves from research into product-building: privacy-conscious AI systems that organize wearable, laboratory, lifestyle, and behavioral data into guidance people and organizations can inspect, evaluate, and act on.
Current roles, research appointments, education, and core research areas
Current work focuses on translating scientific research and engineering methods into interpretable AI systems for health intelligence, multimodal data integration, and responsible deployment.

Explainable AI for Interpretable Health Intelligence
CEO & Founder
Leads Equ Healthcare, a health AI company building explainable systems that integrate wearable, laboratory, lifestyle, and behavioral data into interpretable health intelligence.

Boston, Massachusetts, USA
Director of Research
Directs the Equ Healthcare research group focused on neurosymbolic programming, causal modeling, multimodal health data, and privacy-conscious AI systems.
Research appointments formed the scientific foundation for Omar's current work as a scientist-engineer founder, connecting sensing, computational neuroscience, digital phenotyping, medical engineering, and neurosymbolic AI.

Massachusetts Institute of Technology (MIT), Cambridge, USA
Research Scientist & Research Project Manager
At MIT CSAIL, worked on neurosymbolic programming for scientific discovery, developing methods that connect data-driven learning with symbolic representations, executable models, and interpretable reasoning.

Massachusetts Institute of Technology (MIT), Boston, USA
Postdoctoral research fellow, Edelman Lab
At MIT IMES, worked in a translational medical engineering environment on digital phenotyping, behavioral signals, and AI methods for mental health research.

Massachusetts Institute of Technology (MIT), Boston, USA
Postdoctoral associate and fellow
Picower Institute of Learning and Memory Miller Laboratory
At MIT Brain and Cognitive Sciences and the Picower Institute, applied machine learning to neural signals, learning, memory, and cortical dynamics.
Academic training in electronics engineering, electrical engineering, sensing systems, machine learning, and computational methods.
Additional training in machine learning, artificial intelligence for robotics, parallel programming, big data analytics, signal processing, wireless networks, systems modeling, and bioinformatics.
Core areas across digital mental health AI, symbolic regression, neurosymbolic programming, sensing, computational neuroscience, and responsible product translation.
Models for smartphone-delivered interventions, treatment response, digital phenotyping, and behavioral health signals.
Hybrid neural-symbolic systems for program synthesis, reusable abstractions, and inspectable reasoning.
Equation synthesis methods for compact scientific models, learned concept libraries, and recursive symbolic search.
AI methods that turn experimental, biomedical, and behavioral data into hypotheses and models people can inspect.
Machine learning for neural signals, oscillations, cognition, learning, memory, and cortical dynamics.
Wearable, laboratory, lifestyle, and behavioral data pipelines for interpretable health intelligence.
Spatio-temporal modeling for gait, footstep recognition, tomography sensors, and indoor positioning.
Privacy-conscious, human-reviewable systems that move research into health and scientific workflows.
Scientific trajectory, technical methods, and product-facing focus
A path from engineering and sensing to computational neuroscience, digital mental health, neurosymbolic scientific discovery, and health AI products.

Builds health AI systems that connect wearable, laboratory, lifestyle, and behavioral data with interpretable product workflows.

Worked on neurosymbolic programming, symbolic regression, learned abstractions, and equation synthesis for scientific discovery.

Conducted research on digital phenotyping, smartphone-delivered interventions, behavioral signals, and AI methods for mental health.

Applied machine learning to neural oscillations, learning, memory, and cortical mechanisms at the Picower Institute.

Developed spatio-temporal pattern recognition methods for sensor-based gait analysis in healthcare and security. Thesis: Pattern recognition from raw spatio-temporal data for gait analysis in healthcare and security.
Researched wireless sensing, indoor localization, robotics, and machine learning.

Built an engineering foundation in electronics, systems thinking, applied computing, and technical leadership.
Technical methods spanning health outcome modeling, digital phenotyping, symbolic regression, program synthesis, neural signals, sensing, localization, robotics, and product evaluation.
Methods spanning clinical outcome modeling, symbolic AI, mobile sensing, neuroscience, multimodal health data, spatial systems, robotics, and product evaluation.
Active method family
Predictive and interpretable models for depression, anxiety comorbidity, body dysmorphic disorder, and smartphone-delivered interventions.
Profile evidence
Recent Journal of Affective Disorders and arXiv work on smartphone-delivered mental health interventions.
Where AI research, engineering practice, medical science, and product development come together.
Wearable, laboratory, lifestyle, clinical, and behavioral signals connected into interpretable health models.
Smartphone-delivered interventions, treatment-response prediction, and mobile-sensing studies in mental health.
Symbolic regression, recursive equation synthesis, and learned concept libraries for inspectable models.
Machine learning for electrophysiology, oscillations, cognition, learning, memory, and cortical dynamics.
Models, interfaces, and documentation that support clinical and product review.
Turning peer-reviewed methods, engineering experience, and health data products into practical systems.
Projects and publications across health AI, symbolic modeling, sensing, and scientific discovery
Selected projects across health AI, symbolic regression, digital phenotyping, scientific discovery, sensing, AI education, and robotics.
Citation-ranked publications across mental health AI, neurosymbolic systems, symbolic regression, sensing, computational neuroscience, and scientific discovery.
519
Citations
11
h-index
12
i10-index
30
Papers
Google Scholar snapshot updated Mar 17, 2026. Since 2020: 352 citations, h-index 9, i10-index 9. Metadata reviewed May 19, 2026.
Learned concept libraries for reusable symbolic regression.
Smartphone-delivered CBT response modeling for body dysmorphic disorder.
Showing top 5 of 30 ranked publications
Omar Costilla-Reyes, Rubén Vera-Rodríguez, Patricia Scully, Krikor B. Ozanyan
Omar Costilla-Reyes, Patricia Scully, Krikor B. Ozanyan
Arya Grayeli, Atharva Sehgal, Omar Costilla-Reyes, Miles Cranmer, Swarat Chaudhuri
Learned concept libraries for reusable symbolic regression.
Omar Costilla-Reyes, Patricia Scully, Krikor B. Ozanyan
Omar Costilla-Reyes, Kamesh Namuduri
View citations, publication metadata, and updates on Google Scholar.
Founder and technical advisory for health AI, digital data products, and research translation
Advisory and technical services for organizations building explainable AI, digital health systems, multimodal data products, and responsible AI strategies.
Guidance for teams building AI systems that require transparent reasoning, evidence pathways, and human-reviewable outputs.
Technical strategy, explainable system design, and research-to-product decisions grounded in evidence and constraints.
Research depth with implementation and governance focus
AI education, responsible adoption, research collaboration, entrepreneurship, and ecosystem work
Work across AI education, responsible adoption, research collaboration, entrepreneurship, and international technology ecosystems.
Directing research on explainable AI, multimodal health data fusion, neurosymbolic systems, and privacy-conscious AI systems.
Leading a health AI company focused on building explainable systems that integrate wearable, laboratory, lifestyle, and behavioral data.
Visit websiteContributing to regional science, technology, and AI policy discussions across the Americas.
Visit websiteCoordinating mentorship to support broader participation in AI research.
Advanced computer-aided programming and neurosymbolic methods for scientific discovery.
Visit websiteManaged interdisciplinary research for the NSF-supported Understanding the World Through Code project.
Visit websiteWays to start a focused conversation
Reach out for research collaboration, technical advisory, consulting, or speaking opportunities.
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