A physiologically grounded model of pulmonary acinus for translational research

Exposure Information

No presentational view available as no exposures have been published for this workspace.

Workspace Summary

Description

A novel, multi-compartment computational model of the pulmonary acinus, integrating pneumatic, hemodynamic, and chemical transport dynamics. The model represents the acinus as parallel alveolar compartments and incorporates mechanisms such as hypoxic pulmonary vasoconstriction and pharmacological modulation. It allows for direct simulation of pathophysiological states by tuning parameters for airway obstruction, alveolar collapse, and gas exchange impairment.

Owner

Jagir Hussan <r.jagir@auckland.ac.nz>

URI for git clone/pull/push

https://models.physiomeproject.org/workspace/d42

Report an issue with this workspace

Files